Severe Bradycardia due to Mad-Honey Intoxication in Two Patients

In order to make the diagnosis of mad honey poisoning, which can rarely cause life-threatening situations, excessive and fresh honey consumption as well as the patient's current complaints should be questioned in medical history

📌 3 Key Takeaways

🎯

Objective & Hypothesis:Mad Honey Poisoning occurs with the consumption of honey produced from nectar and pollen of Rhododendron flowers, located in the forest areas of the Black Sea region in Turkey, containing grayanotoxin.

📊

Key Findings & Data:Poisoning is caused by the excessive consumption of fresh and pungent honey containing grayanotoksin.

💡

Conclusion & Impact:In order to make the diagnosis of mad honey poisoning, which can rarely cause life-threatening situations, excessive and fresh honey consumption as well as the patient's current complaints should be questioned in medical history

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Domain Parameters

Abstract

Mad Honey Poisoning occurs with the consumption of honey produced from nectar and pollen of Rhododendron flowers, located in the forest areas of the Black Sea region in Turkey, containing grayanotoxin. Poisoning is caused by the excessive consumption of fresh and pungent honey containing grayanotoksin. Cardiovascular and gastrointestinal complaints are common in these cases. In order to make the diagnosis of mad honey poisoning, which can rarely cause life-threatening situations, excessive and fresh honey consumption as well as the patient's current complaints should be questioned in medical history

Özet

Deli Bal Zehirlenmesi, Türkiye'de özellikle Karadeniz bölgesinin ormanlık alanlarında yer alan Rhodedendron çiçeklerinin grayanotoksin içeren nektar ve polenlerinden üretilen balın tüketilmesi ile meydana gelir. Zehirlenme grayanotoksin içeren taze ve keskin kokulu balın aşırı tüketilmesi ile olmaktadır. Olgularda gastrointestinel yakınmalar ve kardiyovasküler sisteme ait bozukluklar sık görülür. Nadiren de olsa yaşamı tehdit eden durumlara neden olabilen deli bal zehirlenmesinin tanısını koyabilmek için, hastanın mevcut şikâyetlerinin yanında, anamnezinde aşırı ve taze bal tüketim bilgisini sorgulamak gerekmektedir

🔖

Cite This Article

KALDIRIM, Ü., BALTA, Ş., ARDIÇ, Ş., DEMİRKOL, S., TAVLAŞOĞLU, M., ÜNLÜ, M. (2014). Severe Bradycardia due to Mad-Honey Intoxication in Two Patients. Gülhane Tıp Dergisi, Cilt: 56 - Sayı: 4, 248–250. https://ajindex.com/articles/213671

📄 Full Text PDF Viewer

Open in New Tab ↗

↗New Tab

📄

PDF görüntüleyici hazırlanıyor...

References (8)

Stevens PF. Rhododendron L. In: Davis PF, editor. Flora of Turkey and the East Aegean Islands. Edinburgh: Edinburgh University Press; 1978. p. 90-4
Gunduz A, Bostan H, Turedi S, Nuhoğlu I, Patan T. Wild flowers and mad honey. Wilderness Environ Med 2007;18:69-71
Maejima H, Kinoshita E, Seyama I, Yamaoka K. Distinct sites regulating grayanotoxin binding and unbinding to D4S6 of Na(v)1.4 sodium channel as revealed by improved estimation of toxin sensitivity. J Biol Chem 2003;278:9464-71
Gündüz A, Türedi S, Nerede üretilen ballar deli çıkabilir. Türkiye Acil Tıp Dergisi Turk J Emerg Med 2008;8(1):46- 49 5. Yilmaz O, Eser M, Sahiner A, Altintop L, Yesildag O. Hypotension, bradycardia and syncope caused by honey poisoning. Resuscitation 2006;68:405- 8
Cagli KE, Tufekcioglu O, Sen N et al. Atrioventricular Block Induced By Mad-Honey Intoxication. Tex Heart Inst J 2009;36(4):342-4
Gunduz A, Durmus İ, Turedi S, Nuhoglu I, Ozturk S. Mad honey poisoning related asystole. Emerg Med J 2007;24:592–593
Çavuş UY, Işık B, Tekin O. Deli bal zehirlenmesi. Yeni Tıp Dergisi 2010;27: 187-189 9. Dursunoglu D, Gur S, Semiz E. A Case with complete atrioventricular block related to mad honey intoxication. Ann Emerg Med 2007;50: 484–5
Demircan A, Keleş A, Bildik F, Aygencel G, Doğan NO, Gómez HF. Mad honey sex: therapeutic misadventures from an ancient biological weapon. Ann Emerg Med 2009;54: 824-9