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Journals / Dokuz Eylül Üniversitesi Tıp Fakültesi Dergisi / 2002 / Cilt: 16 - Sayı: 2

A case with homozygous familial hypercholesterolemia performed coronary bypass due to premature coronary arteriosclerosis

Erken koroner aterosklerozu nedeniyle bypass yapılan homozigot ailevi hiperkolesterolemili bir olgu

Nurettin ÜNAL
Mustafa KÖSECİK
Sağın Gül SAYLAM
Mustafa KIR
Şebnem PAYTONCU
Soner KUMTEPE
Adnan AKÇORAL
Yeşim ÖZTÜRK
Nur ARSLAN
Benal BÜYÜGEBİZ
Ömer KOZAN
Öztekin OTO
Pages
101–105
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Then, the case was perfomed coronary bypass.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The most important complication of homozigous familial hypercholesterolemia that presents with plain skin xanthomas is premature coronary arteriosclerosis.
📊
Key Findings & Data:We present a fourteen-year-old girl with familial hypercholesterolemia whose plasma total cholesterol and LDL levels remained high despite diet and antihyperlipidemic therapy during 9 years of following.
💡
Conclusion & Impact:Then, the case was perfomed coronary bypass.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Kolesterol · Hiperkolesterolemi · ailevi

Abstract

The most important complication of homozigous familial hypercholesterolemia that presents with plain skin xanthomas is premature coronary arteriosclerosis. We present a fourteen-year-old girl with familial hypercholesterolemia whose plasma total cholesterol and LDL levels remained high despite diet and antihyperlipidemic therapy during 9 years of following. She was asymptomatic, but her late routine exercise test positive, therefore selective coronary angiography was performed, which revealed atherosclerotic occlusion in the right and left main coronary artery. Then, the case was perfomed coronary bypass.

Özet

Düz deri ksantomaları ile belirti veren homozigot ailevi hiperkolesteroleminin en korkulan komplikasyonu erken koroner aterosklerozdur. Dokuz yıllık klinik izleminde diyet ve ilaçla plazma total kolesterol ve LDL düzeyleri düşürülemeyen, rutin kardiyolojik kontrolde efor testinin pozitif olması nedeni ile yapılan selektif koroner anjiografide sağ ve sol ana koroner arterlerde darlık tespit edilen ve koroner bypass operasyonu yapılan ailevi hiperkolesterolemili 14 yaşındaki kız olgu sunuldu.

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Cite This Article

ÜNAL, N., KÖSECİK, M., SAYLAM, S. G., KIR, M., PAYTONCU, Ş., KUMTEPE, S., AKÇORAL, A., ÖZTÜRK, Y., ARSLAN, N., BÜYÜGEBİZ, B., KOZAN, Ö., OTO, Ö. (2002). A case with homozygous familial hypercholesterolemia performed coronary bypass due to premature coronary arteriosclerosis. Dokuz Eylül Üniversitesi Tıp Fakültesi Dergisi, Cilt: 16 - Sayı: 2, 101–105. https://ajindex.com/articles/213396

References (13)

  1. Gidding SS. Preventive pediatric cardiology. Tobacco, cholesterol, obesity, and physical activity. Pediatric Clinics of North America 1999;46:253-262
  2. Tershakovec AM, Cootes PM, Cortner JA. Disorders of Hpoprotein metabolism and transport. In: Behrman RE, Kliegman RM, Arvin MA (eds): Nelson Texbook of Pediatrics, 15th ed. Philadelphia, WB. Saunders; 1996;p:1319-1320
  3. Kwiterovich PO. identification and treatment of heterozigous familial hypercholestrolemia in children and adolescents. Am J Cardiol 1993;72:30-37
  4. Shamir R, Fisher EA. Dietary therapy for children with hypercholesterolemia. Am Fam Physician 2000;6:675-682
  5. Duplaga BA. Treatment of childhood hypercholesterolemia with HMG-CoA reductase inhibitors. Ann Pharmacother 1999;33:1224-1227
  6. Barbagallo CM, Averna MR, Dimarco T, et al. Effectiveness of cascade filtration plasmapheresis in two patients affected by familial hypercholesterolemia. Journal of Clinical Apheresis 1995;10:96-100
  7. Yüksel B, Karademir M, Yılmaz M ve ark. Ailevi homozigot hiperkolesterolemili iki olgu ve tedavide plazma değişimi yönteminin uygulanması. İst Çocuk Klin Derg 1994;29:123-126
  8. Ülgen MS, Gürkan F, Toprak N. Familiyal homozigot hiperkolesterolemili olgular ve kardiovasküler değerlendirme. Medikal Network Kardiyoloji 2001;8: 214-217
  9. Kawaguchi A, Miyatake K, Yutanı C, et al. Characteristic cardiovascular manifestation in homozigous and heterozigous familial hypercholesterolemia. Am Heart J 1999;137:410-418
  10. Pihkala J, Nykanen D, Freedom RM, et al. İntervantional cardiac catheterization. Pediatric Clinics of North America 1999;46:441-463
  11. McCauley KM, Schanne LC, Wilensky RL. Case study: analysis of an acte anterior-lateral myocardial infarction in a 16-year-old patient with familial hypercholestrolemia. J Cardiovasc Nurs 1999;13:114-118
  12. Windhagen-Mahnert B, Paul T, Offner G, et al. Severe stenosis of the right coronary artery in a 15-year-old girl with type Ha hypercholesterolemia: successful treatment with stent implantation. Z Kardiol 1997;86:727-731
  13. Bonnet D, Bonhoeffer P, Sidi D, et al. Surgical angioplasty of the main coronary arteries in children. J Thorac Cardivasc Surg 1999;! 17:352-357.