AI Summary & Key Takeaways
AI InsightOther parameters were not significantly different between the two types of nodules.CONCLUSIONThe absence of fat and fibrous capsule, and presence of en-hancement at three minutes appear to be most characteristic for mICC and may help its differentiation from pHCC
📌 3 Key Takeaways
Özet
PURPOSEWe aimed to gain further insight in magnetic resonance im-aging characteristics of mass-forming intrahepatic cholangio-carcinoma (mICC), its enhancement pattern with gadoxetic acid contrast agent, and distinction from poorly differentiat-ed hepatocellular carcinoma (pHCC).METHODSFourteen mICC and 22 pHCC nodules were included in this study. Two observers recorded the tumor shape, intratumoral hemorrhage, fat on chemical shift imaging, signal intensity at the center of the tumor on T2-weighted image, fibrous capsule, enhancement pattern on arterial phase of dynamic study, late enhancement three minutes after contrast injec-tion (dynamic late phase), contrast uptake on hepatobiliary phase, apparent diffusion coefficient, vascular invasion, and intrahepatic metastasis. RESULTSLate enhancement was more common in mICC (n=10, 71%) than in pHCC (n=3, 14%) (P < 0.001). A fat component was observed in 11 pHCC cases (50%) versus none of mICC cases (P = 0.002). Fibrous capsule was observed in 13 pHCC cases (59%) versus none of mICC cases (P < 0.001). On T2-weight-ed images a hypointense area was seen at the center of the tumor in 43% of mICC (6/14) and 9% of pHCC (2/22) cases (P = 0.018). Other parameters were not significantly different between the two types of nodules.CONCLUSIONThe absence of fat and fibrous capsule, and presence of en-hancement at three minutes appear to be most characteristic for mICC and may help its differentiation from pHCC