Journals / Haseki Tıp Bülteni / 2016 / Cilt: 54 - Sayı: 3

Elektif Sezaryen Seksiyolarda İntratekal Bupivakaine Eklenen Fentanil ve Morfinin Maternal ve Yenidoğan Üzerine Etkileri

Comparison of the Maternal and Neonatal Effects of Intratechal Bupivacaine Plus Fentanyl or Morphine During Cesarean Delivery

Pages
152–157
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Conclusion:­Fentanyl and morphine added to intrathecal bupivacaine show similar effects in intraoperative analgesia.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim:­To evaluate the effects of morphine and fentanyl added to bupivacaine and intrathecal bupivacaine to combine spinal-epidural anaesthesia during caesarean.Methods:­Forty subjects with American Society of Anesthesiologists I-II status who would have caesarean were included in the study.
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Key Findings & Data:Group bupivacaine-fentanyl (BF) were given 0.5% bupivacaine 7.5 mg + 25 ?g fentanyl and group bupivacaine-morphine (BM) received 0.5% bupivacaine 7.5 mg + 0.1 mg morphine intrathecal total 2 mL.
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Conclusion & Impact:Conclusion:­Fentanyl and morphine added to intrathecal bupivacaine show similar effects in intraoperative analgesia.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim:­To evaluate the effects of morphine and fentanyl added to bupivacaine and intrathecal bupivacaine to combine spinal-epidural anaesthesia during caesarean.Methods:­Forty subjects with American Society of Anesthesiologists I-II status who would have caesarean were included in the study. The subjects were divided into two groups. Group bupivacaine-fentanyl (BF) were given 0.5% bupivacaine 7.5 mg + 25 ?g fentanyl and group bupivacaine-morphine (BM) received 0.5% bupivacaine 7.5 mg + 0.1 mg morphine intrathecal total 2 mL. Periods for access to T4 block, two dermatome regression of sensory block, time elapsed between the administration of the local anaesthetic and reaching Bromage scale 1, reaching the highest level of motor block, first analgesic necessity, umbilical cord clamping time, and when the operation ends were recorded. One-minute and five-minute Apgar scores, umbilical blood gas values of the newborns and the adverse effects were recorded.Results: Comparisons between the two groups show that group BM has longer periods for motor block start time, two dermatome regression time, and first anaesthetic necessity time and group BF had higher levels for motor block level at the 1st minute and visual analog scale scores at postop 60th minute. There was no significant difference between the groups for the adverse effects. Conclusion:­Fentanyl and morphine added to intrathecal bupivacaine show similar effects in intraoperative analgesia. We

Özet

Amaç:­ Sezaryenlerde kombine spinal-epidural anestezide intratekal bupivakain ve bupivakaine eklenen fentanil ve morfinin etkilerini değerlendirmektir.Yöntemler: Sezaryen operasyonu geçirecek Amerikan Anestezi Derneği I-II grubunda, 40 olgu çalışmaya alındı. Olgular iki gruba ayrıldı. Grup bupivakain-fentanile (BF) 7,5 mg %0,5 bupivakain + 25 µg fentanil, grup bupivakain-morfine (BM) 7,5 mg %0,5 bupivakain + 0,1 mg morfin intratekal olarak total 2 mL verildi. T4 duyusal bloğa ulaşma, duyusal bloğun iki dermatom gerileme, lokal anestezinin verilmesinden Bromage skalasının 1 olma süreleri, motor bloğun en üst skalaya ulaşma süresi, motor bloğun tamamen kaybolma süresi, ilk analjezik ihtiyacı süresi, bebeğin umblikal korda klemp konma süresi, operasyon bitim süresi kaydedildi. Olguların deri ve uterus insizyonu, periton kapatma, postoperatif 30 dakika, 60 dakika ve ağrı duydukları andaki ağrı şiddetleri ve ulaşılan en üst motor blok skalası kaydedildi. Yenidoğan birinci-beşinci dakika Apgar değerleri ve umblikal kan gazı değerleri ve yan etkiler kaydedildi.Bulgular:­Gruplar arasında yapılan karşılaştırmalarda, grupların motor blok başlama zamanı, iki dermatom gerileme süresi, ilk analjezik ihtiyacı süresi grup BM'de uzun bulunurken, birinci dakika motor blok seviyesi ve postop 60 dakika visuel analog skalaları ise grup BF'de daha yüksek bulundu. Yan etkiler açısından gruplar arasında anlamlı farklılık bulunmadı

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Cite This Article

YILDIRIM, A., SUBAŞI, F. D., KUPLAY, Y., TURAN, G., EKİNCİ, O., BOSNA, G. (2016). Elektif Sezaryen Seksiyolarda İntratekal Bupivakaine Eklenen Fentanil ve Morfinin Maternal ve Yenidoğan Üzerine Etkileri. Haseki Tıp Bülteni, Cilt: 54 - Sayı: 3, 152–157. https://ajindex.com/articles/213013

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