Journals / Experimental Biomedical Research / 2021 / Cilt: 4 - Sayı: 2

Evaluation of electrocardiographic ventricular repolarization parameters in stable coronary artery disease

Pages
141–147
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Several surface ECG predictors of ventricular arrhythmias, including QTd, JT and Tp-e intervals and their ratios to QT and JT, are not significantly correlated with SYNTAX score-assessed CAD severity in patients with stable angina pectoris

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: To examine the relationship between the SYNTAX score (SS) and cardiac repolarization parameters such as cQTd and Tp-e values, and Tp-e/QT, Tp-e/JT, Tp-e/QTc, and Tp-e/JTc ratios in patients who have stable angina pectoris.
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Key Findings & Data:Methods: 12-lead resting electrocardiograms (ECGs) and SS of 160 patients (51 female and 109 male) undergoing coronary angiography with the pre-diagnosis of stable angina pectoris were evaluated.
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Conclusion & Impact:Conclusion: Several surface ECG predictors of ventricular arrhythmias, including QTd, JT and Tp-e intervals and their ratios to QT and JT, are not significantly correlated with SYNTAX score-assessed CAD severity in patients with stable angina pectoris
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Aim: To examine the relationship between the SYNTAX score (SS) and cardiac repolarization parameters such as cQTd and Tp-e values, and Tp-e/QT, Tp-e/JT, Tp-e/QTc, and Tp-e/JTc ratios in patients who have stable angina pectoris. Methods: 12-lead resting electrocardiograms (ECGs) and SS of 160 patients (51 female and 109 male) undergoing coronary angiography with the pre-diagnosis of stable angina pectoris were evaluated. Patients with a SS below 22 were classified as Group 1 (low-SYNTAX), and those above 22 (high-SYNTAX) as Group 2. Forty-four patients with normal coronary angiography were included in Group 3. Results: Mean age of the patients was 62.4±9.1 years. The heart rate, QRS, QT, cQT and JT durations between the groups were similar. In addition, relatively recent ventricular repolarization indices such as Tp-e interval and Tp-e/QT, Tp-e/JT, Tp-e/QTc, and Tp-e/JTc ratios were also not substantially different between groups. Conclusion: Several surface ECG predictors of ventricular arrhythmias, including QTd, JT and Tp-e intervals and their ratios to QT and JT, are not significantly correlated with SYNTAX score-assessed CAD severity in patients with stable angina pectoris

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Cite This Article

COŞGUN, M., ERDAL, E., GÜNEŞ, Y., SİNCER, İ., MANSIROĞLU, A. (2021). Evaluation of electrocardiographic ventricular repolarization parameters in stable coronary artery disease. Experimental Biomedical Research, Cilt: 4 - Sayı: 2, 141–147. https://ajindex.com/articles/212421

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References (14)

  1. Nowbar AN, Gitto M, Howard JP, at al. Mortality From Ischemic Heart Disease. Circ Cardiovasc Qual Outcomes. 2019
  2. 12(6): e005375. [2]Sara JD, Eleid MF, Gulati R, et al. Sudden Cardiac Death From the Perspective of Coronary Artery Disease. Mayo Clin Proc. 2014
  3. 89(12):1685-98. [3]Priori SG, Blomström-Lundqvist C, Mazzanti A, et al. Task Force for the Management of Patients with Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death of the European Society of Cardiology (ESC). Europace. 2015
  4. 17(11):1601-87. [4]Engel G, Beckerman JG, Froelicher VF, et al. Electrocardiographic arrhythmia risk testing. Curr Probl Cardiol. 2004
  5. 29(7):365- 32. [5]Turakhia M, Tseng ZH. Sudden cardiac death: epidemiology, mechanisms, and therapy. Curr Probl Cardiol. 2007
  6. 32(9):501–46. [6]Castro-Torres Y, Carmona-Puerta R, Katholi RE. Ventricular repolarization markers for predicting malignant arrhythmias in clinical practice. World J Clin Cases. 2015
  7. 3(8):705-20. [7]Crow RS, Hannan PJ, Folsom AR. Prognostic significance of corrected QT and corrected JT interval for incident coronary heart disease in a general population sample stratified by presence or absence of wide QRS complex: the ARIC Study with 13 years of follow-up. Circulation. 2003
  8. 108(16):1985-89. [8]Gupta P, Patel C, Patel H et al. T(p-e)/QT ratio as an index of arrhythmogenesis. J Electrocardiol. 2008
  9. 41(6):567–74. [9]Castro-Torres Y. Tpeak-Tend/QT: un nuevo predictor electrocardiográfico de muerte súbita cardíaca. Cardiocore. 2014
  10. 49(2):86– 87. [10]Sianos G, Morel MA, Kappetein AP, et al. The SYNTAX score: an angiographic tool grading the complexity of coronary artery disease. Euro Intervention. 2005
  11. 1(2):219– 27. [11]Valgimigli M, Serruys PW, Tsuchida K, et al. Cyphering the complexity of coronary artery disease using the syntax score to predict clinical outcome in patients with three-vessel lumen obstruction undergoing percutaneous coronary intervention. Am J Cardiol. 2007
  12. 99(8):1072– 81. [12]Lemesle G, Bonello L, de Labriolle A, et al. Prognostic value of the Syntax score in patients undergoing coronary artery bypass grafting for three-vessel coronary artery disease. Catheter Cardiovasc Interv. 2009
  13. 73(5):612–17. [13]Capodanno D, Di Salvo ME, Cincotta G, et al. Usefulness of the SYNTAX score for predicting clinical outcome after percutaneous coronary intervention of unprotected left main coronary artery disease. Circ Cardiovasc Interv. 2009
  14. 2(4):302-8. [14]Bazett HC. An analysis of the time relations of