Journals / Kocaeli Tıp Dergisi / 2014 / Cilt: 3 - Sayı: 3

Role of ultrasound elastography in the differential diagnosis of benign and malignant thyroid nodules

Benign ve malign tiroid nodüllerinin ayırıcı tanısında ultrason elastografinin rolü

Pages
21–25
DOI
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Results: On real-time ultrasound elastography, 48 of 49 benign nodules had a score of 1 to 3, 5 of 7 malign nodules had a score of 4 to 5 (p<0.001), with sensitivity of 71%, specificity of 97%, a positive predictive value of 83%, and a negative predictive value of Conclusion: Ultrasound elastography is a usefull imaging technique in the differential diagnosis of thyroid cancer.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The purpose of this study was to evaluate the diagnostic utility of ultrasound elastography in differentiating benign Methods: A total of 52 consecutive patients who were referred for thyroid fine needle aspiration biopsy were examined in this study. 56 thyroid nodules in these patients were examined by B-mode ultrasound and ultrasound elastography.
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Key Findings & Data:The final diagnosis was obtained from histologic findings.Tissue stiffness on US elastography was scored from one (greatest elastic strain) to five (no strain).
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Conclusion & Impact:Results: On real-time ultrasound elastography, 48 of 49 benign nodules had a score of 1 to 3, 5 of 7 malign nodules had a score of 4 to 5 (p<0.001), with sensitivity of 71%, specificity of 97%, a positive predictive value of 83%, and a negative predictive value of Conclusion: Ultrasound elastography is a usefull imaging technique in the differential diagnosis of thyroid cancer.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: The purpose of this study was to evaluate the diagnostic utility of ultrasound elastography in differentiating benign Methods: A total of 52 consecutive patients who were referred for thyroid fine needle aspiration biopsy were examined in this study. 56 thyroid nodules in these patients were examined by B-mode ultrasound and ultrasound elastography. The final diagnosis was obtained from histologic findings.Tissue stiffness on US elastography was scored from one (greatest elastic strain) to five (no strain). Results: On real-time ultrasound elastography, 48 of 49 benign nodules had a score of 1 to 3, 5 of 7 malign nodules had a score of 4 to 5 (p<0.001), with sensitivity of 71%, specificity of 97%, a positive predictive value of 83%, and a negative predictive value of Conclusion: Ultrasound elastography is a usefull imaging technique in the differential diagnosis of thyroid cancer.

Özet

Amaç: Bu çalışmadaki amacımız, tiroid nodüllerinde benignmalign ayrımında US elastografinin katkısını araştırmaktır. Gereç ve yöntem: Kliniğimize tiroid ince iğne aspirasyon biyopsisi (İİAB) için refere edilen 52 hasta çalışmaya dahil edildi. 56 tiroid nodülü çalışmaya dahil edildi ve tüm nodüller B-mod ultrasonografi ve elastografi ile değerlendirildi.İİAB ve elastografi sonuçları karşılaştırıldı.Elastisite skorlaması 1' den (nodülün tümünde elastisite var) 5' e kadar (nodülde ve posterior gölgelenmede elastisite yok) olacak şekilde yapıldı. Bulgular: 49 benign nodülün 48' inde skor1-3 arası, 7 malign nodülün 5' inde skor 4-5 olarak değerlendirildi (p<0.05). Sensitivite, spesifite, pozitif prediktif değer (PPV) ve negatif prediktif değer (NPV) sırasıyla; %71, %97, %83, %68 olarak hesaplandı. Elastografinin genel gücü (test geçerliliği) %94 olarak Sonuç: Ultrason elastografi, tiroid kanseri ayırıcı tanısında faydalı bir yöntemdir.

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Cite This Article

DUYGULU, G., ÖZER, T., CEBECİ, H., TİRYAKİ, Ç., COŞKUN, M., ERUYAR, A. T. (2014). Role of ultrasound elastography in the differential diagnosis of benign and malignant thyroid nodules. Kocaeli Tıp Dergisi, Cilt: 3 - Sayı: 3, 21–25. https://ajindex.com/articles/211258

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