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Journals / Acta Orthopaedica et Traumatologica Turcica / 2015 / Cilt: 49 - Sayı: 4

Immunohistochemical analysis of mechanoreceptors in transverse acetabular ligament and labrum: a prospective analysis of 35 cases

Kasım KILIÇARSLAN
AYDAN KILIÇARSLAN
İSMAİL DEMİRKALE
Mahmut Nedim AYTEKİN
MEHMET ATIF EROL AKSEKİLİ
MAHMUT UĞURLU
Pages
394–398
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

However, TAL and labrum free nerve fibers suggest potential roles as hip pain generators

📌 3 Key Takeaways

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Objective & Hypothesis:The labrum and transverse acetabular ligament (TAL) are classically described as distinct anatomical structures with abundant mechanoreceptors and free nerve fibers.
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Key Findings & Data:This study evaluated the microscopic anatomy of the labrum and TAL and specifically investigated the neurological status of these structures.Methods: Labral and TAL specimens from 35 consecutive patients with coxarthrosis undergoing total hip arthroplasty were dissected into a total of 4 specimens per hip.
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Conclusion & Impact:However, TAL and labrum free nerve fibers suggest potential roles as hip pain generators
🔬Design:Research Article
📍Scope:4 specimens
⚙️Variables:Domain Parameters

Abstract

The labrum and transverse acetabular ligament (TAL) are classically described as distinct anatomical structures with abundant mechanoreceptors and free nerve fibers. They deepen the joint and act as natural barriers against dislocation, thus providing additional stability. We hypothesized that severe coxarthrosis leads to elimination of labrum and TAL mechanoreceptors. This study evaluated the microscopic anatomy of the labrum and TAL and specifically investigated the neurological status of these structures.Methods: Labral and TAL specimens from 35 consecutive patients with coxarthrosis undergoing total hip arthroplasty were dissected into a total of 4 specimens per hip. Formaldehyde-fixed specimens were evaluated for the presence of mechanoreceptors and free nerve endings by neurofilament protein and S-100 protein immunohistochemistry and microscopy.Results: Mechanoreceptors were identified in the labral (2.3/high power field) but not TAL specimens, with a sharp delineation between the tissues. In contrast, both labrum and TAL showed good vascularity with abundant free nerve fibers within fibrous connective tissue (mean, 2.6 sensory fibers/high power field vs 3.1/high power field, respectively).Conclusion: This study demonstrated that the TAL lacks mechanoreceptors. However, TAL and labrum free nerve fibers suggest potential roles as hip pain generators

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Cite This Article

KILIÇARSLAN, K., KILIÇARSLAN, A., DEMİRKALE, İ., AYTEKİN, M. N., AKSEKİLİ, M. A. E., UĞURLU, M. (2015). Immunohistochemical analysis of mechanoreceptors in transverse acetabular ligament and labrum: a prospective analysis of 35 cases. Acta Orthopaedica et Traumatologica Turcica, Cilt: 49 - Sayı: 4, 394–398. https://ajindex.com/articles/210928

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