Journals / Anadolu Psikiyatri Dergisi / 2015 / Cilt: 16 - Sayı: 6

Fog cloud in front of the lewy bodies dementia: delirium

Lewy cisimcikli demansın önündeki sis bulutu: Deliryum

Pages
451–453
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this case, we present a woman who had difficulty for diagnosis due to misdiagnosis of LCD and treatment with quetiapine and rivastigmine

📌 3 Key Takeaways

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Objective & Hypothesis:Lewy body dementia (LBD) is the second most common form of dementia after Alzheimer disease.
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Key Findings & Data:Antipsychotic medication for the treatment of delirium worsens the symptoms due to neuroleptic sensitivity associated with increased morbidity and mortality patients with LBD.
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Conclusion & Impact:In this case, we present a woman who had difficulty for diagnosis due to misdiagnosis of LCD and treatment with quetiapine and rivastigmine
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Lewy body dementia (LBD) is the second most common form of dementia after Alzheimer disease. Clinical symptoms include acute onset of cognitive fluctuations accompanied by dementia, visual hallucinations, disorientation and sleep disorders that suggest initially the diagnosis of delirium. Antipsychotic medication for the treatment of delirium worsens the symptoms due to neuroleptic sensitivity associated with increased morbidity and mortality patients with LBD. In literature, there are rare case reports with overlooked LBD that presented like delirium symptoms. Additionally, it was declared that quetiapine and cholinesterase inhibitors have individually efficacy on treatment of LBD. In this case, we present a woman who had difficulty for diagnosis due to misdiagnosis of LCD and treatment with quetiapine and rivastigmine

Özet

Lewy cisimcikli demans (LCD) Alzheimerdan sonra en sık görülen demans türüdür, demansa eşlik eden akut başlangıçlı bilişsel dalgalanmalar, yönelim bozukluğu, görsel varsanılar ve uyku bozuklukları ön planda deliryum tanısını akla getirir. Deliryum tedavisinde yeğlenen antipsikotik tedaviler LCD’da karşılaşılan morbidite ve mortalite ile ilişkili nöroleptik duyarlılığı nedeniyle tabloyu kötüleştirir. Literatürde deliryum bulguları ile görülmesi nedeniyle LCD tanısı gözden kaçan nadir olgu sunumları vardır. Ayrıca LCD tedavisinde tek başına ketiyapin veya kolinesteraz inhibitörleri ile etkinlik elde edildiği bildirilmiştir. Bu yazıda deliryum tablosu nedeniyle tanısında güçlük yaşanan ve çeşitli tedavileri tolere edemeyen bir kadın hastanın ketiyapin ve rivastigmin kombinasyonu ile tedavisi sunulmuştur. (Anadolu Psikiyatri Derg 2015; 16(6):451-453)

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Cite This Article

YÜCEL, N., YUCEL, A., AYDIN, N. (2015). Fog cloud in front of the lewy bodies dementia: delirium. Anadolu Psikiyatri Dergisi, Cilt: 16 - Sayı: 6, 451–453. https://ajindex.com/articles/210654

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References (17)

  1. Li X, Rastogi P, Gibbons JA, Chaudhury S. Visuocognitive skill deficits in Alzheimer's disease and Lewy body disease: A comparative analysis. Ann Indian Acad Neurol 2014; 17:12-18
  2. Zaccai J, McCracken C, Brayne C. A systematic review of prevalence and incidence studies of dementia with Lewy bodies. Age Ageing 2005; 34:561-566
  3. Ghika J. [Diffuse Lewy body disease]. Rev Med Suisse Romande 2000; 120:843-846
  4. Kosaka K. Lewy body disease and dementia with Lewy bodies. Proc Jpn Acad Ser B Phys Biol Sci 2014; 90:301-306
  5. Zweig YR, Galvin JE. Lewy body dementia: the impact on patients and caregivers. Alzheimers Res Ther 2014; 6:21
  6. Fujishiro H, Iseki E, Nakamura S, Kasanuki K, Chiba Y, Ota K, et al. Dementia with Lewy bodies: early diagnostic challenges. Psychogeriatrics 2013; 13:128-138
  7. Gleason OC. Delirium. Am Fam Physician 2003:1027-1034
  8. Vasilevskis EE, Han JH, Hughes CG, Ely EW. Epidemiology and risk factors for delirium across hospital settings. Best Pract Res Clin Anaesthesiol 2012; 26:277-287
  9. Gore RL, Vardy ER, O'Brien JT. Delirium and dementia with Lewy bodies: distinct diagnoses or part of the same spectrum? J Neurol Neurosurg Psychiatry 2015; 86:50-59
  10. Hasegawa N, Hashimoto M, Yuuki S, Honda K, Yatabe Y, Araki K, et al. Prevalence of delirium among outpatients with dementia. Int Psychogeriatr 2013; 25:1877-1883
  11. Wang HF, Yu JT, Tang SW, Jiang T, Tan CC, Meng XF, et al. Efficacy and safety of cholinesterase inhibitors and memantine in cognitive impairment in Parkinson's disease, Parkinson's disease dementia, and dementia with Lewy bodies: systematic review with meta-analysis and trial sequential analysis. J Neurol Neurosurg Psychiatry 2014; 86:135-143
  12. Mosimann UP, McKeith IG. Dementia with lewy bodies--diagnosis and treatment. Swiss Med Wkly 2003; 133:131-142
  13. McKeith IG, Dickson DW, Lowe J, Emre M, O'Brien JT, Feldman H, et al. Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium. Neurology 2005; 65:1863-1872
  14. Bourdenx M, Bezard E, Dehay B. Lysosomes and alpha-synuclein form a dangerous duet leading to neuronal cell death. Front Neuroanat 2014; 8:83
  15. Kovari E, Horvath J, Bouras C. Neuropathology of Lewy body disorders. Brain Res Bull 2009; 80:203-210
  16. Spillantini MG, Schmidt ML, Lee VM, Trojanowski JQ, Jakes R, Goedert M. Alpha-synuclein in Lewy bodies. Nature 1997; 388:839-840
  17. Vardy E, Holt R, Gerhard A, Richardson A, Snowden J, Neary D. History of a sus