Journals / Journal of Urological Surgery / 2016 / Cilt: 3 - Sayı: 3

Prostatın Skuamöz Hücre Karsinomu Tedavisinde Kombine Hormonoterapi ve Radyoterapi: Olgu Sunumu Eşliğinde Literatür Değerlendirmesi

Combined Radiation and Hormonal Therapy for Squamous Cell Carcinoma of the Prostate: A Case Report and Review of the Literature

Pages
98–100
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Combined radiotherapy and hormone therapy may hold promise for longer survival.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Squamous cell carcinoma (SCC) of the prostate is a rare entity, with a prevalence of 0.6-1% among all prostatic carcinomas.
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Key Findings & Data:Prostatic SCC has a poor prognosis.
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Conclusion & Impact:Combined radiotherapy and hormone therapy may hold promise for longer survival.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Squamous cell carcinoma (SCC) of the prostate is a rare entity, with a prevalence of 0.6-1% among all prostatic carcinomas. Prostatic SCC has a poor prognosis. Although there are a number of treatment modalities, none of them have promised a long-term survival. Herein, we report a case of SCC coexisting with adenocarcinoma of the prostate treated with a combination of hormonal therapy, leuprolide acetate, and radiotherapy. Twenty-four months after treatment, the patient did not progress into metastatic or end-stage disease with the combination treatment modality. The treatment modalities for SCC are still limited. Comparisons of surgery and radiotherapy, and chemotherapy and hormonal therapy showed that they were all ineffective. Combined radiotherapy and hormone therapy may hold promise for longer survival.

Özet

Prostatın skuamöz hücreli karsinom (SHK) tüm prostat karsinom arasında %0,6-1 prevalansı ile nadir görülen bir durumdur. SHK kötü prognoza sahiptir. Çeşitli tedavi modaliteleri olmasına rağmen, bunların hiçbiri uzun süreli yaşam vaat etmezler. Bu yazıda hormon tedavisi ve radyoterapi kombinasyonu ile tedavi olan adenokarsinom birlikteliği ile olan prostatik SHK olgusu sunuldu. Yirmi dört ay tedavi sonrası, hastada kombinasyon tedavi yöntemi ile metastatik ya da son evre hastalık haline ilerleme olmadı. SHK için tedavi yöntemleri hala sınırlı olmasına rağmen kombine radyo ve hormonoterapi bu hastalık için uzun yaşam süresini vaat edebilir.

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Cite This Article

KILINÇ, M. F., KARAKAN, T., ÖZER, E., DEMİR, D. O., AYDOĞMUŞ, Y., DOLUOĞLU, Ö. G. (2016). Prostatın Skuamöz Hücre Karsinomu Tedavisinde Kombine Hormonoterapi ve Radyoterapi: Olgu Sunumu Eşliğinde Literatür Değerlendirmesi. Journal of Urological Surgery, Cilt: 3 - Sayı: 3, 98–100. https://ajindex.com/articles/210488

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