Quantitative liver tumor blood volume measurements by a C-arm CT post-processing software before and after hepatic arterial embolization therapy: comparison with MDCT perfusion
Objective & Hypothesis:C-arm CT imaging was performed on a flat-detector angiographic system (Ar- tis Zee, Siemens Healthcare) according to the injection and acquisition proto- col shown in Fig. 1.
📊
Key Findings & Data:The following pa- rameters were used in data acquisition: acquisition time approximately 5 s, 90 kV, 616×480 matrix, projection on 30×40 cm flat panel, 200° total angle, 0.8°/frame, 248 frames total, detector entrance dose 0.36 µGy/frame.
💡
Conclusion & Impact:A total volume of 36 mL of contrast
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Abstract
C-arm CT imaging was performed on a flat-detector angiographic system (Ar- tis Zee, Siemens Healthcare) according to the injection and acquisition proto- col shown in Fig. 1. The C-arm CT BV acquisition consists of two runs: an ini- tial rotation (mask scan) followed by a second rotation after contrast medium injection (fill scan). The following pa- rameters were used in data acquisition: acquisition time approximately 5 s, 90 kV, 616×480 matrix, projection on 30×40 cm flat panel, 200° total angle, 0.8°/frame, 248 frames total, detector entrance dose 0.36 µGy/frame. Con- trast injection starts immediately after the mask run and is maintained until the end of the fill run. The C-arm ro- tates back, which takes another 5-6 s, then the fill run starts. By then the contrast has been distributed through the arteries and the parenchyma has reached a homogeneous enhancement. A total volume of 36 mL of contrast
🔖
Cite This Article
AKATA, D., ÖZMEN, M. N., BALKANCI, F. (2015). Quantitative liver tumor blood volume measurements by a C-arm CT post-processing software before and after hepatic arterial embolization therapy: comparison with MDCT perfusion. Diagnostic and Interventional Radiology, Cilt: 21 - Sayı: 1, 71–77. https://ajindex.com/articles/210281
In conclusion, based on our limited data, quantitative BV measurement with C-arm CT is a feasible technique pies. Significant decrease in tumor BV tion. Irrespective of histopathological type, both primary and metastatic ma- lignancies are suitable for BV measure- ment using the C-arm CT technique. The BV measurement of these tumors before the embolization treatment is indicative of their vascularity accord ing to their origins. Conflict of interest disclosure The authors declared no conflicts of interest. Miles KA, Hayball M, Dixon AK. Colour perfusion imaging: a new application of computed tomography. Lancet 1991;:643-645. [CrossRef] 2. Ackerman NB, Lien WM, Kondi ES, et al. The blood supply of experimental liver metastases. I: the distribution of hepatic artery and portal vein blood to "small" and "large" tumors. Surgery 1970; 66:1067-1072. 3. Archer SG, Gray BN. Vascularization of small liver metastases. Br J Cancer 1989; 76:545-548. 4. Kennedy A, Coldwell D, Sangro B, Wasan H, Salem R. Radioembolization for the treatment of liver tumors gen eral principles. Am J Clin Oncol 2012;:91-99. [CrossRef] 5. Kennedy A, Nutting C, Coldwell D, et al. Pathologic response and microdosimetry of 90Y microspheres in man: review of four explanted whole livers. Int J Radiat Oncol Biol Phys 2004; 60:1552-1563. [CrossRef] 6. Lau WY, Lai EC. Hepatocellular carci noma: current management and recent advances. Hepatobiliary Pancreas Dis Int; 7:237-257. 7. Zellerhoff M, Deuerling-Zheng Y, Stroth er CM, et al. Measurement of cerebral BV using angiographic C-arm systems. Paper presented at SPIE Medical Imaging, Inter national Society for Optics and Photon ics; February 26, 2009;
Florida, USA. 8. Ganguly A, Fieselmann A, Marks M, et al. Cerebral CT perfusion using an inter ventional C-arm imaging system: cerebral blood flow measurements. Am J Neurora diol 2011; 32:1525-1531. [CrossRef] 9. Struffert T, Deuerling-Zheng Y, Kloska S, et al. Flat detector CT in the evaluation of brain parenchyma, intracranial vascu lature, and cerebral BV: a pilot study in patients with acute symptoms of cere bral ischemia. Am J Neuroradiol 2010;:1462-1469. [CrossRef] 10. Struffert T, Deuerling-Zheng Y, Kloska S, et al. Cerebral BV imaging by flat detector computed tomography in comparison to conventional multislice perfusion CT. Eur Radiol 2011; 21:882-889. [CrossRef] 11. Spira D, Schulze M, Sauter A, et al. Vol ume perfusion-CT of the liver: Insights and applications. Eur J Radiol 2012;:1471-1