Journals / Düşünen Adam - Psikiyatri ve Nörolojik Bilimler Dergisi / 2013 / Cilt: 26 - Sayı: 2

Alkol bağımlılarında normal karar verme ve yürütücü işlevler

Normal Decision-making and executive functions in alcohol dependent individuals

Pages
131–138
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: The results suggest that our sample of pure AD do not have global deficits in decision-making as measured by the IGT and that their poor decisions regarding their alcohol consumption are limited to drinking.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Normal decision-making and executive functions in alcohol dependent individuals Objective: Decision-making processes have become a principal target of study among addiction researchers.
📊
Key Findings & Data:However, studies are often hampered by two significant methodological challenges: multi-substance dependence and comorbid conditions, which are independently associated with neurocognitive impairments.
💡
Conclusion & Impact:Conclusion: The results suggest that our sample of pure AD do not have global deficits in decision-making as measured by the IGT and that their poor decisions regarding their alcohol consumption are limited to drinking.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Normal decision-making and executive functions in alcohol dependent individuals Objective: Decision-making processes have become a principal target of study among addiction researchers. However, studies are often hampered by two significant methodological challenges: multi-substance dependence and comorbid conditions, which are independently associated with neurocognitive impairments. The purpose of this study was to compare alcohol dependent subjects without any comorbidity, with controls on a measure of decision-making and executive functions and to examine the interrelationship among these measures. Methods: We compared 30 alcohol-dependent (AD) male patients with 30 matched male healthy controls regarding their performances on the Iowa Gambling Task, Wisconsin Card Sorting Test, Stroop Test, Auditory Consonant Trigram Test and the Category Naming Test. Results: The AD group was not significantly more impaired compared to controls on any test. Only working memory scores were associated with decision-making scores in the total group. Conclusion: The results suggest that our sample of pure AD do not have global deficits in decision-making as measured by the IGT and that their poor decisions regarding their alcohol consumption are limited to drinking.

Özet

Amaç: Karar verme (KV) süreci, bağımlılık alanındaki çalışmaların ana hedefi haline gelmiştir. Ancak, bağımlılarda sık görülen yüksek miktarda çoklu madde kullanımı ve psikiyatrik eştanı birlikteliği, KV çalışmalarının iki önemli yöntemsel kısıtlılığını oluşturmaktadır. Bu çalışmanın amacı, birinci ve ikinci eksende herhangi bir psikopatolojisi olmayan alkol bağımlılarında (AB) ve kontrol grubunda KV ve yürütücü işlevlerin karşılaştırılması ve KV ile yürütücü işlevler arasındaki ilişkinin araştırılmasıdır. Yöntem: Çalışmada 30 alkol bağımlısı erkek hasta ve 30 eşleştirilmiş sağlıklı erkek kontrol grubunun Iowa Kumar Testi (IKT), Wisconsin Kart Eşleme Testi, Stroop Testi, Sözel Akıcılık Testi ve İşitsel Üçlü Sessiz Harf Sıralaması Testi puanları karşılaştırılmıştır. Bulgular: Alkol bağımlısı grup ile sağlıklı kontrol grubu arasında, yapılan hiçbir testte herhangi bir anlamlı fark saptanmamıştır. Toplam grupta sadece işleyen bellek puanlarıyla KV arasında ilişki saptanmıştır. Sonuç: Sonuçlarımız, ‘saf’ AB’de IKT ile ölçülen KV’deki bozulmanın sadece alkol kullanımıyla sınırlı olduğunu ve genel bir bozulma olmadığını düşündürtmektedir.

🔖

Cite This Article

ZORLU, N., EKMEN, D. D., POLAT, S., KUSERLİ, A., GÜLSEREN, Ş. (2013). Alkol bağımlılarında normal karar verme ve yürütücü işlevler. Düşünen Adam - Psikiyatri ve Nörolojik Bilimler Dergisi, Cilt: 26 - Sayı: 2, 131–138. https://ajindex.com/articles/209605

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Bechara A. Risky business: emotion, decision-making, and addiction. J Gambl Stud 2003; 19:23-51
  2. Bechara A, Damasio AR. The somatic marker hypothesis: a neural theory of economic decision. Games Econ Behav 2005; 52:336-372
  3. Bechara A, Damasio AR, Damasio H, Anderson SW. Insensitivity to future consequences following damage to human prefrontal cortex. Cognition 1994; 50:7-15
  4. Bechara A, Tranel D, Damasio H. Characterization of the decision-making deficit of patients with ventromedial prefrontal cortex lesions. Brain 2000; 123:2189-2202
  5. Mazas CA, Finn PR, Steinmetz JE. Decision-making biases, antisocial personality, and early-onset alcoholism. Alcohol Clin Exp Res 2000; 24:1036-1040
  6. Grant S, Contoreggi C, London ED. Drug abusers show impaired performance in a laboratory test of decision making. Neuropsychologia 2000; 38:1180-1187
  7. Hanson KL, Luciana M, Sullwold K. Reward-related decision- making deficits and elevated impulsivity among MDMA and other drug users. Drug and Alcohol Dependence 2008; 96:99- 110
  8. Verdejo-Garcia A, Perez-Garcia M. Profile of executive deficits in cocaine and heroin polysubstance users: common and differential effects on separate executive components. Psychopharmacology 2007; 190:517-530
  9. Fein G, McGillivary S, Finn P. Normal performance on a simulated gambling task in treatment-naive alcohol dependent individuals. Alcohol Clin Exp Res 2006; 30:959-966
  10. Finn PR, Mazas CA, Justus AN, Steinmetz J. Early-onset alcoholism with conduct disorder: go/no go learning deficits, working memory capacity, and personality. Alcohol Clin Exp Res 2002; 26:186-206
  11. Quednow BB, Kühn K, Hoppe C, Westheide J, Maier W, Daum I, Wagner M. Elevated impulsivity and impaired decision- making cognition in heavy users of MDMA (“Ecstasy”). Psychopharmacology 2007; 189:517-530
  12. Adinoff, B, Devous MD, Cooper DB, Best SE, Chandler P, Harris T, Cervin CA, Cullum CM. Resting regional cerebral blood flow and gambling task performance in cocaine-dependent subjects and healthy comparison subjects. Am J Psychiatry 2003; 160:1892-1894
  13. Bechara, A, Dolan S, Hindes A. Decision-making and addiction (part II): myopia for the future or hypersensitivity to reward? Neuropsychologia 2002; 40:1690-1705
  14. Buelow MT, Suhr JA. Construct validity of the Iowa Gambling Task. Neuropsychology Rev 2009; 19:102-114. 15. van der Plas EA, Crone EA, van den Wildenberg WP, Tranel D, Bechara A. Executive control deficits in substance- dependent indi