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Journals / Kırıkkale Üniversitesi Tıp Fakültesi Dergisi / 2020 / Cilt: 22 - Sayı: 2

Scaffolding Biomaterials in Regenerative Endodontics

REJENERATİF ENDODONTİDE İSKELE BİYOMATERYALLERİ

Dilek HANÇERLİOĞULLARI
Ali ERDEMİR
Pages
281–287
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The aim of this review is to define the types of scaffolding used in regenerative treatments and to evaluate the current literature study results.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:In tissue engineering; physiological and functional restoration of tissue lost due to cancer, trauma or diseases is targeted.
📊
Key Findings & Data:The concept of regeneration with a multidisciplinary approach includes stem cells, scaffolds and growth factors.
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Conclusion & Impact:The aim of this review is to define the types of scaffolding used in regenerative treatments and to evaluate the current literature study results.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Rejeneratif endodonti · iskeleler · kök hücreler

Abstract

In tissue engineering; physiological and functional restoration of tissue lost due to cancer, trauma or diseases is targeted. The concept of regeneration with a multidisciplinary approach includes stem cells, scaffolds and growth factors. For successful treatments, artificial extracellular matrices (scaffolds) that support tissue formation during the organization and vascularization of stem cells are needed. Scaffolding design is critically important for tissue engineering. Tissue engineering has also shown promising results in the field of dentistry. Research data showed that smaller sizes of dental tissue can be produced instead of the whole crown of the tooth. In regenerative endodontic treatments, natural and fabricated scaffolds are used. The aim of this review is to define the types of scaffolding used in regenerative treatments and to evaluate the current literature study results.

Özet

Doku mühendisliğiyle; kanser, travma ya da hastalıklar nedeniyle kaybolan dokunun fizyolojik ve fonksiyonel restorasyonu hedeflenir. Rejenerasyon kavramı multidisipliner bir yaklaşımla; kök hücreler, iskele ve büyüme faktörlerini içermektedir. Tedavilerin daha başarılı olabilmesi için kök hücrelerinin organizasyonu ve vaskülarizasyonu sırasında doku oluşumunu destekleyen geçici ekstrasellüler matrikslere (iskeleler) ihtiyaç vardır. İskele tasarımı, doku mühendisliği için kritik öneme sahiptir. Doku mühendisliğiyle, diş hekimliği alanında da umut vaat edici sonuçlara ulaşılmıştır. Araştırma verileri; dişin tüm kronu yerine daha küçük boyutlarda diş dokusunun üretilebildiğini göstermiştir. Rejeneratif endodontik tedavilerde, doğal ve doğal olmayan (fabrikasyon) iskeleler kullanılır. Bu derlemenin amacı, rejeneratif tedavilerde kullanılan iskele çeşitlerinin tanımlanması ve güncel literatür çalışma sonuçlarının değerlendirilmesidir.

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Cite This Article

HANÇERLİOĞULLARI, D., ERDEMİR, A. (2020). Scaffolding Biomaterials in Regenerative Endodontics. Kırıkkale Üniversitesi Tıp Fakültesi Dergisi, Cilt: 22 - Sayı: 2, 281–287. https://ajindex.com/articles/209442

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