Journals / Haseki Tıp Bülteni / 2016 / Cilt: 54 - Sayı: 2

Intraperitoneal Hemorrhage in a Peritoneal Dialysis Patient Using Dabigatran: A Case Report

Dabigatran Kullanan Periton Diyalizi Hastasında İntraperitoneal Hemoraji: Olgu Sunumu

Pages
118–119
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Despite the low risk of intracranial hemorrhage, clinicians should be careful in patients with chronic kidney disease because coagulation monitoring is not possible.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Dabigatran is used for the prevention of stroke and systemic embolism in patients with nonvalvular atrial fibrillation.
📊
Key Findings & Data:In this paper, we present a case of intraperitoneal hemorrhage in a 54-years-old male peritoneal dialysis patient using dabigatran for paroxysmal atrial fibrillation because international normalized ratio level could not be kept at target levels during follow-up.
💡
Conclusion & Impact:Despite the low risk of intracranial hemorrhage, clinicians should be careful in patients with chronic kidney disease because coagulation monitoring is not possible.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Dabigatran is used for the prevention of stroke and systemic embolism in patients with nonvalvular atrial fibrillation. It is still unclear whether the use of dabigatran leads to more bleeding compared with warfarin. In this paper, we present a case of intraperitoneal hemorrhage in a 54-years-old male peritoneal dialysis patient using dabigatran for paroxysmal atrial fibrillation because international normalized ratio level could not be kept at target levels during follow-up. The use of dabigatran in atrial fibrillation has become widespread in recent years. Despite the low risk of intracranial hemorrhage, clinicians should be careful in patients with chronic kidney disease because coagulation monitoring is not possible.

Özet

Dabigatran nonvalvular atriyal fibrilasyon hastalarında inme ve sistemik emboliyi önlenmek için kullanılır. Dabigatranın kullanımının varfarin ile karşılaştırıldığında dabigatranın daha fazla kanamaya yol açıp açmayacağı hala belirsizdir. Bu yazıda 54 yaşında, intraperitoneyal hemoraji ile başvuran, takiplerinde uluslararası normalleştirilmiş oranı düzeyleri istenilen düzeyde tutulamadığından paroksismal atriyal fibrilasyon nedeni ile dabigatran kullanan periton diyalizi hastası sunduk. Atriyal fibrilasyonda dabigatran kullanımı yıllar içinde artış göstermiştir. İntrakraniyal kanama riski az olmasına rağmen kronik böbrek hastalarında koagülasyon takibi yapılamadığından dabigatran kullanırken dikkatli olmalıyız.

🔖

Cite This Article

CEBECİ, E., SAMANCI, N. Ş., GÜRSU, M., ŞUMNU, A., KARADAĞ, S., UZUN, S., TATLI, E., BEHLÜL, A., KOÇ, L., AYDIN, Z., ÖZTÜRK, S. (2016). Intraperitoneal Hemorrhage in a Peritoneal Dialysis Patient Using Dabigatran: A Case Report. Haseki Tıp Bülteni, Cilt: 54 - Sayı: 2, 118–119. https://ajindex.com/articles/208312

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (7)

  1. Hernandez I, Baik SH, Piñera A, Zhang Y. Risk of bleeding with dabigatran in atrial fibrillation. JAMA Intern Med 2015;175:18-24
  2. Stangier J. Clinical pharmacokinetics and pharmacodynamics of the oral direct thrombin inhibitor dabigatran etexilate. Clin Pharmacokinet 2008;47:285-95
  3. Ezekowitz MD, Reilly PA, Nehmiz G, et al. Dabigatran with or with out concomitant aspirin compared with warfarin alone in patients with nonvalvular atrial fibrillation (PETRO Study). Am J Cardiol 2007;100:1419-26
  4. Connolly SJ, Ezekowitz MD, Yusuf S, et al. Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med;361:1139-51
  5. Glund S, Moschetti V, Norris S, et al. A randomised study in healthy volunteers to investigate the safety, tolerability and pharmacokinetics of idarucizumab, a specific antidote to dabigatran. Thromb Haemost 2015;113:943-51
  6. Schulman S, Kearon C, Kakkar AK, et al. Extended use of dabigatran, warfarin, or placebo in venous thromboembolism. N Engl J Med 2013;368:709-18
  7. Chan KE, Edelman ER, Wenger JB, Thadhani RI, Maddux FW. Dabigatran and rivaroxaban use in atrial fibrillation patients on hemodialysis. Circulation 2015;131:972-9.