Journals / Haseki Tıp Bülteni / 2016 / Cilt: 54 - Sayı: 2

A Case of Fatal Congenital Human Immunodeficiency Virus Infection

Fatal Seyirli Bir Konjenital İnsan İmmün Yetmezlik Virüsü Enfeksiyonu Olgusu

Pages
106–111
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Here, we present the case of a 60-day-old infant heavily immunocompromised due to an extremely high viral burden of HIV, which was acquired perinatally from an undiagnosed and untreated mother, leading to severe bronchopneumonia, sepsis, septic shock and death.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Acquired immune deficiency syndrome is a clinical condition caused by human immunodeficiency virus (HIV) which can be transmitted either vertically or horizontally.
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Key Findings & Data:More than 90% of children living with HIV in developing countries have been infected through mother to child transmission during pregnancy, around the time of birth, or through breastfeeding.
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Conclusion & Impact:Here, we present the case of a 60-day-old infant heavily immunocompromised due to an extremely high viral burden of HIV, which was acquired perinatally from an undiagnosed and untreated mother, leading to severe bronchopneumonia, sepsis, septic shock and death.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Acquired immune deficiency syndrome is a clinical condition caused by human immunodeficiency virus (HIV) which can be transmitted either vertically or horizontally. More than 90% of children living with HIV in developing countries have been infected through mother to child transmission during pregnancy, around the time of birth, or through breastfeeding. In order to reduce the number of infected children, increasing emphasis should be placed on preventing mother to child transmission programs with the use of antiretroviral medications in the pregnant woman during pregnancy and at delivery and, starting immediately after birth for the exposed infant. Here, we present the case of a 60-day-old infant heavily immunocompromised due to an extremely high viral burden of HIV, which was acquired perinatally from an undiagnosed and untreated mother, leading to severe bronchopneumonia, sepsis, septic shock and death.

Özet

Edinsel bağışıklık yetmezliği sendromu vertikal veya horizontal olarak bulaşabilen insan immun yetmezlik virüsünün (HİV) neden olduğu bir klinik tablodur. Gelişmekte olan ülkelerde HİV ile enfekte çocukların %90'ından fazlası bu virüse gebelik boyunca, doğum esnasında ya da emzirmeyle anneden bebeğe bulaş yoluyla maruz kalmış olan çocuklardır. Enfekte çocuk sayısını azaltmak için antiretroviral ilaç tedavilerinin enfekte gebelerde gebelik boyunca ve doğum esnasında kullanımı, risk altındaki bebeklerde de doğar doğmaz başlanması suretiyle anneden-bebeğe-bulaş önleyici programların üstünde daha fazla durulmalıdır. Bu olguda; tanı almamış ve tedavi olmamış bir annenin perinatal dönemde enfekte olan, aşırı derecede yüksek HİV viral yüküne bağlı olarak ağır immün yetmezlik gelişen ve bunun sonucunda ciddi bronkopnömoni, sepsis, ve septik şok nedeniyle eksitus olan 60 günlük bebeği sunulmaktadır.

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Cite This Article

HATİPOĞLU, H. U., ELEVLİ, M., BUDAN, A. B. Ç., DURU, H. N. S., ÇİVİLİBAL, M., KARAKUŞ, A. (2016). A Case of Fatal Congenital Human Immunodeficiency Virus Infection. Haseki Tıp Bülteni, Cilt: 54 - Sayı: 2, 106–111. https://ajindex.com/articles/208310

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