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Journals / ANKEM Dergisi / 2005 / Cilt: 19 - Sayı: 3

In vitro susceptibility of fusidic acid in methicillin-resistant Staphylococcus aureus strains isolated from various clinical specimens by broth microdilution method

Çeşitli klinik örneklerden izole edilen metisiline dirençli Staphylococcus aureus suşlarında fusidik asit duyarlılığının sıvı mikrodilüsyon yöntemi ile araştırılması

Feryal ÖZTÜRK
Gözde ÖNGÜT
HADİYE DEMİRBAKAN
Duygu DAĞLAR
Filiz KIZILATEŞ
Dilara ÖĞÜNÇ
Meral GÜLTEKİN
Pages
135–138
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We concluded that fusidic acid may be used as an additive alternative drug for treatment of nosocomial MRSA infections.

📌 3 Key Takeaways

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Objective & Hypothesis:Susceptibility of 162 methicillin-resistant Staphylococcus aureus (MRSA) strains isolated from various clinical specimens from February 2003 to June 2004 were tested for fusidic acid by broth microdilution method.
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Key Findings & Data:The values of MIC50/MIC90 of fusidic acid for MRSA strains were determined as 0.1210.06 fig/ml.
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Conclusion & Impact:We concluded that fusidic acid may be used as an additive alternative drug for treatment of nosocomial MRSA infections.
🔬Design:Research Article
📍Scope:2003 Verileri
⚙️Variables:Metisilin direnci · Staphylococcus aureus · Mikrobiyal duyarlılık testleri

Abstract

Susceptibility of 162 methicillin-resistant Staphylococcus aureus (MRSA) strains isolated from various clinical specimens from February 2003 to June 2004 were tested for fusidic acid by broth microdilution method. The values of MIC50/MIC90 of fusidic acid for MRSA strains were determined as 0.1210.06 fig/ml. Of all the isolates 159 (98 %) were susceptible to fusidic acid. We concluded that fusidic acid may be used as an additive alternative drug for treatment of nosocomial MRSA infections.

Özet

Şubat 2003-Haziran 2004 tarihleri arasında çeşitli klinik örneklerden izole edilen 162 metisiline dirençli Staphylococcus aureus (MRSA) susunda fusidik asit duyarlılığı sıvı mikrodilüsyon yöntemiyle araştırılmıştır. Çalışmaya alınan MRSA suşlarının MİK90İMÎK.50 değerleri 0.1210.06 lglml olarak saptanmıştır. Suşların I59'u (% 98) fusidik aside duyarlı bulunmuştur. Bu duyarlılık oram ilefusidik asidin özellikle hastane infeksiyonlarında sık karşılaşılan MRSA infeksiyonlarının tedavisinde alternatif bir ilaç olarak değerlendirilebileceği sonucuna varılmıştır.

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Cite This Article

ÖZTÜRK, F., ÖNGÜT, G., DEMİRBAKAN, H., DAĞLAR, D., KIZILATEŞ, F., ÖĞÜNÇ, D., GÜLTEKİN, M. (2005). In vitro susceptibility of fusidic acid in methicillin-resistant Staphylococcus aureus strains isolated from various clinical specimens by broth microdilution method. ANKEM Dergisi, Cilt: 19 - Sayı: 3, 135–138. https://ajindex.com/articles/208185

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