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Journals / art / 2020 / Cilt: 35 - Sayı: 1

Diagnostic Sensitivity of Different Applications of Pathergy Test for Behçet’s Disease

İncilay KALAY YILDIZHAN
Ayse BOYVAT
Journal
art
Pages
29–34
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Further studies are needed to develop new applications of pathergy test that would increase the sensitivity and which are also easy to apply.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objectives: This study aims to compare the sensitivity of the intradermal application of the pathergy test with the “three-step pathergy test”.
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Key Findings & Data:Patients and methods: The study included 60 patients with Behçet's disease (BD) (23 males, 37 females; mean age 33.9±9.7 years; range, 11 to 57 years) and 100 patients with recurrent aphthous stomatitis as the control group (39 males, 61 females; mean age 32.4±12.1 years; range, 11 to 66 years).
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Conclusion & Impact:Further studies are needed to develop new applications of pathergy test that would increase the sensitivity and which are also easy to apply.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Objectives: This study aims to compare the sensitivity of the intradermal application of the pathergy test with the “three-step pathergy test”. Patients and methods: The study included 60 patients with Behçet's disease (BD) (23 males, 37 females; mean age 33.9±9.7 years; range, 11 to 57 years) and 100 patients with recurrent aphthous stomatitis as the control group (39 males, 61 females; mean age 32.4±12.1 years; range, 11 to 66 years). Simultaneous intradermal pathergy test and three-step pathergy test were applied to each patient. Results: Twenty-six patients (43.3%) with BD had positive three-step pathergy test and 18 (30%) of them had positive intradermal pathergy test. A statistically significant relationship was found between the three-step pathergy test positivity and male sex while no relationship was detected between the disease activity and the positivity of the pathergy test. In the three-step pathergy test, pathergy positivity with intramuscular method was statistically significantly higher than with intravenous method. Conclusion: The three-step pathergy test in patients with BD was found to have higher sensitivity compared with the intradermal pathergy test. The intramuscularly applied pathergy test was the main cause of increase in sensitivity. Further studies are needed to develop new applications of pathergy test that would increase the sensitivity and which are also easy to apply.

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Cite This Article

YILDIZHAN, İ. K., BOYVAT, A. (2020). Diagnostic Sensitivity of Different Applications of Pathergy Test for Behçet’s Disease. art, Cilt: 35 - Sayı: 1, 29–34. https://ajindex.com/articles/206039

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References (15)

  1. Blobner F. Zur rezidivierenden Hypopyoniritis. Z Augenheilkd 1937;91:129-39
  2. Erdem C, Gürler A, Kundakçı N. Behçet hastalarında üç aamalı paterji testi ile elde edilen sonuçlar. Lepr Mec 1987;18:73-84
  3. Criteria for diagnosis of Behçet’s disease. International Study Group for Behçet’s Disease. Lancet 1990;335:1078-80
  4. International Team for the Revision of the International Criteria for Behcet’s Disease. Evaluation of the International Criteria for Behcet’s disease (ICBD) Clinical and Experimental Rheumatology 2006;24(Suppl 42):S13
  5. Gürler A, Boyvat A, Türsen U. Clinical manifestations of Behçet’s disease: an analysis of 2147 patients. Yonsei Med J 1997;38:423-7
  6. Dogan B, Taskapan O, Harmanyeri Y. Prevalance of pathergy test positivity in Behçet’s disease in Turkey. J Eur Acad Dermatol Venereol 2003;17:228-9
  7. Lee ES, Bang D, Lee S. Dermatologic manifestation of Behçet’s disease. Yonsei Med J 1997;38:380-9
  8. Yazici H, Chamberlain MA, Tüzün Y, Yurdakul S, Müftüoglu A. A comparative study of the pathergy reaction among Turkish and British patients with Behçet’s disease. Ann Rheum Dis 1984;43:74-5
  9. Davies PG, Fordham JN, Kirwan JR, Barnes CG, Dinning WJ. The pathergy test and Behçet’s syndrome in Britain. Ann Rheum Dis 1984;43:70-3
  10. Tüzün Y, Yurdakul S, Cem Mat M, Ozyazgan Y, Hamuryudan V, Tüzün B, et al. Epidemiology of Behçet’s syndrome in Turkey. Int J Dermatol 1996;35:618-20
  11. International Team for the Revision of the International Criteria for Behçet’s Disease (ITRICBD). The International Criteria for Behçet's Disease (ICBD): a collaborative study of 27 countries on the sensitivity and specificity of the new criteria. J Eur Acad Dermatol Venereol 2014;28:338-47
  12. Atalay A, Arıkan S, Ozturk O, Öncü M, Tasli ML, Duygulu S, et al. The IL-8 Gene Polymorphisms in Behçet’s Disease Observed in Denizli Province of Turkey. Immunol Invest 2016;45:298-311
  13. Aydin F, Akpolat T, Senturk N, Bagci H, Yasar Turanli A. Evaluation of pathergy test positivity in familial Mediterranean fever patients and comparison of clinical manifestations of FMF with Behçet’s disease. Clin Rheumatol 2009;28:1331-5
  14. Balta I, Akbay G, Kalkan G, Eksioglu M. Demographic and clinical features of 521 Turkish patients with Behçet’s disease. Int J Dermatol 2014;53:564-9
  15. Alli N, Gur G, Yalcin B, Hayran M. Patient characteristics in Behçet disease: a retrospective analysis of 213 Turkish patients during 2001-4. Am J Clin Dermatol 2009;10:411-8