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Journals / Haydarpaşa Numune Medical Journal / 2019 / Cilt: 59 - Sayı: 3

An ABPA Case with an Initial Diagnosis and Treatment of Smear-Negative Pulmonary Tuberculosis

Şeyma ÖZDEN
Arzu DENİZ
Naciye MUTLU
Hüseyin Cem TİGİN
Murat KIYIK
Pages
299–303
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Due to not observing any relief of symptoms after tuberculosis treatment and earlier findings, such as high level of total immunoglobulin E (IgE), presence of peripheral eosinophilia, diagnosis of central bronchiectasis on thorax CT image, positive Aspergillus skin test results and history of asthma, allergic bronchopulmonary aspergillosis (ABPA) was considered and verified by cytologic examination of specimens obtained through fiberoptic bronchoscopy (FOB).

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Allergic bronchopulmonary aspergillosis (ABPA) is a hypersensitive reaction to a fungus known as Aspergillus fumigatus.
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Key Findings & Data:The differential diagnosis for ABPA is generally not considered before diagnosis and treatment of smear-negative pulmonary tuberculosis.
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Conclusion & Impact:Due to not observing any relief of symptoms after tuberculosis treatment and earlier findings, such as high level of total immunoglobulin E (IgE), presence of peripheral eosinophilia, diagnosis of central bronchiectasis on thorax CT image, positive Aspergillus skin test results and history of asthma, allergic bronchopulmonary aspergillosis (ABPA) was considered and verified by cytologic examination of specimens obtained through fiberoptic bronchoscopy (FOB).
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Allergic bronchopulmonary aspergillosis (ABPA) is a hypersensitive reaction to a fungus known as Aspergillus fumigatus. The differential diagnosis for ABPA is generally not considered before diagnosis and treatment of smear-negative pulmonary tuberculosis. In this study, we present an example case and aim to remind of ABPA. A patient with a history of asthma had increasingly developed shortness of breath and wheezing during asthma treatment. The patient was initially diagnosed with pneumonia based on pulmonary infiltration findings on PA x-ray. Antibiotherapy did not relieve the symptoms, and acid-fast bacteria (AFB) culture was negative. Upon detection of a progression of pulmonary infiltration on the second PA x-ray image, following the antibiotherapy, treein- bud (TIB) opacities and cavitary lesion were observed on computed tomography (CT) of the thorax and the patient was clinically and radiologically diagnosed with tuberculosis. Due to not observing any relief of symptoms after tuberculosis treatment and earlier findings, such as high level of total immunoglobulin E (IgE), presence of peripheral eosinophilia, diagnosis of central bronchiectasis on thorax CT image, positive Aspergillus skin test results and history of asthma, allergic bronchopulmonary aspergillosis (ABPA) was considered and verified by cytologic examination of specimens obtained through fiberoptic bronchoscopy (FOB).

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Cite This Article

ÖZDEN, Ş., DENİZ, A., MUTLU, N., TİGİN, H. C., KIYIK, M. (2019). An ABPA Case with an Initial Diagnosis and Treatment of Smear-Negative Pulmonary Tuberculosis. Haydarpaşa Numune Medical Journal, Cilt: 59 - Sayı: 3, 299–303. https://ajindex.com/articles/205892

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