Journals / KONURALP TIP DERGİSİ / 2017 / Cilt: 9 - Sayı: 3

Evaluation of Blood Parameters in Attention Deficiency and Hyperactivity Disorder

Dikkat Eksikliği ve Hiperaktivite Bozukluğu'nda Kan Parametrelerinin İncelenmesi

Pages
207–212
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Further studies which involve larger population are essential to confirm the results that our findings to be find meaningful.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: Attention deficit hyperactivity disorder (ADHD) is a neuropsychiatric disorder that is common in the paediatric age group.
📊
Key Findings & Data:Methods: The study included 91 children and 115 healthy children between the ages of 5 and 15 years.
💡
Conclusion & Impact:Conclusion: Further studies which involve larger population are essential to confirm the results that our findings to be find meaningful.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Attention deficit hyperactivity disorder (ADHD) is a neuropsychiatric disorder that is common in the paediatric age group. Although some studies have been conducted on this purpose, the etiology has not been fully elucidated. We aimed to contribute on literature about the disease through investigating some blood parameters at pediatric ADHD patients. Methods: The study included 91 children and 115 healthy children between the ages of 5 and 15 years. Serum iron, total iron binding capacity, ferritin, vitamin B12 level, folic acid level, free T4 and thyroid stimulating hormone levels were studied in whole group. Results: The mean age of the patient group was 9.0 ± 2.5 years, the mean age of the control group was 9.7 ± 3.1 years, and there was no difference between them. Male sex ratio was higher in both groups. Significant changes were detected in MCV, RDW, neutrophil count, MPV, plateletcrit (PCT), platelet distribution width (PDW) results between control and experimental groups. Serum iron level was significantly lower in the control group comparing to the patient group. There was no statistical difference between the groups regarding ferritin values. When the results of vitamin B12, folic acid and thyroid function tests were evaluated, no statistically significant difference was found between the groups. Conclusion: Further studies which involve larger population are essential to confirm the results that our findings to be find meaningful.

Özet

Amaç: Dikkat eksikliği ve hiperaktivite bozukluğu (DEHB), pediatrik yaş grubunda yaygın olarak görünen nöropsikiyatrik bir bozukluktur. Nedenine yönelik çok sayıda çalışma yapılmış olsa da etiyoloji tam olarak aydınlatılamamıştır. Biz de DEHB tanılı hastalarda bazı kan parametrelerini araştırarak, hastalıkla ilgili literatüre katkı yapmayı amaçladık. Gereç ve Yöntem: Çalışmaya 5-15 yaş arası 91 hasta ve 116 sağlıklı çocuk dahil edildi. Tüm çocuklardan tam kan sayımı, serum demir, total demir bağlama kapasitesi, ferritin, vitamin B12 düzeyi, folik asit düzeyi, serbest T4 ve tiroid stimulan hormon düzeyleri çalışıldı. Bulgular: Hasta grubunun yaş ortalaması 9,0±2,5 yıl, kontrol grubunun yaş ortalaması 9,7±3,1 yıl saptandı ve aralarında fark yoktu. Her 2 grupta da erkek cinsiyet oranı yüksekti. Gruplar arasında MCV, RDW, nötrofil sayısı, MPV, trombosit yüzdesi (PCT), trombosit dağılım genişliği (PDW) sonuçları açısından anlamlı değişiklikler saptandı. Serum demir düzeyi kontrol grubunda hasta grubuna göre anlamlı olarak düşüktü. Ferritin değerleri açısından gruplar arasında istatistiksel fark saptanmadı. Vitamin B12, folik asit ve tiroid fonksiyon testleri sonuçları değerlendirildiğinde gruplar arasında istatistiksel olarak anlamlı fark bulunamadı. Sonuç: Gruplar arası anlamlı bulduğumuz sonuçları doğrulamak için daha çok sayıda hasta içeren ileri çalışmalara ihtiyaç vardır.

🔖

Cite This Article

ÜSKÜL, H., YILDIRMAK, Z. Y., Özsan, H., KILIÇASLAN, Ö. (2017). Evaluation of Blood Parameters in Attention Deficiency and Hyperactivity Disorder. KONURALP TIP DERGİSİ, Cilt: 9 - Sayı: 3, 207–212. https://ajindex.com/articles/205200

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. Faraone SV, Biederman J, Friedman D. Validity of DSM-IV subtypes of attention-deficit/hyperactivity disorder: A family study perspective. J Am Acad Child Adolesc Psychiatry 2000;39:300-7
  2. Perwien AR, Faries DE, Kratochvil CJ, et al. Improvement in healthrelated quality of life in children with ADHD: An analysis of placebo controlled studies of atomoxetine. J Dev Behav Pediatr 2004;25:264-71
  3. Polanczyk GV, Willcutt EG, Salum GA, et al. ADHD prevalence estimates across three decades: an updated systematic review and meta-regression analysis. Int J Epidemiol 2014;43(2):434-42
  4. Weiss M, Weiss G. Attention deficit hyperactivity disorder. In: Lewis M, ed. Child and Adolescent Psychiatry. A Comprehensive Textbook. 3rd ed. Baltimore; Lippincott, Williams & Wilkins, 2002;645-78
  5. Lahat E, Heyman E, Livne A, et al. Iron deficiency in children with attention deficit hyperactivity disorder. Isr Med Assoc J 2011;13:530-3
  6. Tandon M, Pergjika A. Attention Deficit Hyperactivity Disorder in Preschool-Age Children. Child Adolesc Psychiatr Clin N Am 2017;26(3):523-38
  7. Uyan Z, Peker GC, Tekiner S, et al. Ergenlerde dikkat eksikliği hiperaktivite bozukluğu sıklığının araştırılması. Konuralp Tıp Dergisi 2014;6(3):21-6
  8. Acar ASŞ. Dikkat Eksikliği ve Hiperaktivite Bozukluğu. İn: Yurdakök M. Yurdakök Pediatri. First ed. Ankara: Güneş Tıp Kitapevleri Ltd. Şti, 2017;461-8 9. Durmuş FB, Arman AR, Ayaz AB. Chronotype and its relationship with sleep disorders in children with attention deficit hyperactivity disorder. Chronobiology International 2017;2:1-9
  9. Kwon HJ, Lim MH, Ha M, et al. Transferrin in korean children with attention deficit hyperactivity disorder. Psychiatry Investig 2011;8(4):366-71
  10. Percinel I, Yazici KU, Ustundag B. Iron Deficiency Parameters in Children and Adolescents with AttentionDeficit/Hyperactivity Disorder. Child Psychiatry Hum Dev 2016;47(2):259-69
  11. Garipardic M, Doğan M, Bala KA, et al. Association of Attention Deficit Hyperactivity Disorder and Autism Spectrum Disorders with Mean Platelet Volume and Vitamin D. Med Sci Monit 2017;23:1378-84
  12. Budak YU, Polat M, Huysal K. The use of platelet indices, plateletcrit, mean platelet volume and platelet distribution width in emergency non-traumatic abdominal surgery: a systematic review. Biochem Med 2016;26(2):178-93
  13. Sönmez FT, Güneş H, Sönmez CI, et al. Mean platelet volume as a predictor in acute appendicitis. Global Journal for Research Analysis 2016;5(6):223-5