Journals / Çocuk Enfeksiyon Dergisi / 2012 / Cilt: 6 - Sayı: 3

Pediatric brucellosis: A retrospective evaluation of 82 cases

Çocuklarda bruselloz: 82 Olgunun retrospektif olarak değerlendirilmesi

Pages
74–78
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

In areas where the disease is endemic, it should be considered primarily, especially in patients who present with fever and joint pain. (J Pediatr Inf 2012; 6: 74-8)

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The Southeast Anatolia region of Turkey is a geographic area with endemic brucellosis.
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Key Findings & Data:Material and Methods: A retrospective evaluation was made of 82 cases diagnosed with brucellosis between January 2009 and September 2011 in terms of age, gender, complaints on presentation, risk of infection, family history, physical examination findings, laboratory test results and treatment applied.
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Conclusion & Impact:In areas where the disease is endemic, it should be considered primarily, especially in patients who present with fever and joint pain. (J Pediatr Inf 2012; 6: 74-8)
🔬Design:Research Article
📍Scope:2009 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: The Southeast Anatolia region of Turkey is a geographic area with endemic brucellosis. This study aimed to evaluate brucellosis cases in respect of epidemiology, clinical and laboratory findings and response to treatment. Material and Methods: A retrospective evaluation was made of 82 cases diagnosed with brucellosis between January 2009 and September 2011 in terms of age, gender, complaints on presentation, risk of infection, family history, physical examination findings, laboratory test results and treatment applied. Diagnosis was made by high brucellosis agglutination titer and/or bacterial growth in culture. Results: The cases comprised 37 males and 45 females with a mean age of 11.96±3.57 years (range 5-16 years). The majority of cases (76.8%) were the children of rural families engaged in agriculture and livestock production. The most common reasons for attendance were fever (86.6%), joint pain (75.6%), fatigue (51.2%) and sweating (37.8%). Physical examination determined fever (90.2%), arthritis (26.8%), splenomegaly (22%), hepatomegaly (20.7%) and lymphadenopathy (14.6%). The brucella agglutination titer was ≥1/160 in all cases. Reproduction was seen in the blood culture of 1 patient and in the cerebral spinal fluid of 1 patient. A combination therapy of doxycycline and rifampicin was administered to 68 patients aged 8 years and older, and trimethroprim- sulfamethoxazole (TMP/SMX) and rifampicin to 14 patients under 8 years old. Conclusion: There may be many different clinical signs of brucellosis. In areas where the disease is endemic, it should be considered primarily, especially in patients who present with fever and joint pain. (J Pediatr Inf 2012; 6: 74-8)

Özet

Amaç: Güneydoğu Anadolu bölgesi ülkemizde brusellozun endemik görüldüğü coğrafyada bulunmaktadır. Çalışmamızda bruselloz olgularının epidemiyolojik, klinik, laboratuvar bulguları ve tedavi yanıtlarını değerlendirilmesi amaçlandı. Gereç ve Yöntemler: Ocak 2009-Eylül 2011 tarihleri arasında bruselloz tanısıyla izlediğimiz 82 olgu yaş, cinsiyet, geliş yakınmaları, bulaş yönünden riskleri, aile öyküsü, fizik muayene ve laboratuvar bulguları, uygulanan tedaviler açısından geriye dönük olarak değerlendirmeye alındı. Tanı yüksek brusella aglütinasyon titresi ve/veya kültürde etkenin üretilmesi ile konuldu. Bulgular: Olguların 37’si erkek 45’i kız olup, yaş ortalamaları 11.96±3.57 (yaş aralığı: 5-16) yıl idi. Olguların çoğunu (%76.8) kırsal kesimde yaşayan, tarım ve hayvancılıkla uğraşan ailelerin çocukları oluşturmaktaydı. En sık başvuru nedenleri ateş (%86.6), eklem ağrıları (%75.6), halsizlik (%51.2) ve terleme (%37.8) idi. Fizik muayenede; ateş (%90.2), artrit (%26.8), splenomegali (%22), hepatomegal (%20.7) ve lenfadenopati (%14.6) saptandı. Brusella aglütinasyon titresi tüm olgularda 1/160 ve üzerindeydi. Bir olgunun kan kültüründe, bir olguda beyin omurilik sıvısında üreme oldu. Sekiz yaş ve üzerinde olan 68 hastaya doksisiklin ve rifampisin, sekiz yaş altında olan 14 hastaya trimetoprim-sülfometaksazol (TMP/SMX) ve rifampisin kombinasyon tedavisi uygulanmıştı. Sonuç: Bruselloz çok değişik klinik belirtilerle karşımıza çıkabilmektedir. Hastalığın endemik olduğu bölgelerde özellikle ateş ve eklem ağrısı yakınması olan olgularda öncelikle düşünülmesi gereklidir. (J Pediatr Inf 2012; 6: 74-8)

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Cite This Article

ABUHANDAN, M., GÜZEL, B., ÇAKMAK, A., ÇİÇEK, A. (2012). Pediatric brucellosis: A retrospective evaluation of 82 cases. Çocuk Enfeksiyon Dergisi, Cilt: 6 - Sayı: 3, 74–78. https://ajindex.com/articles/203516

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