Journals / Ege Tıp Dergisi / 2015 / Cilt: 54 - Sayı: 2

Keratokistik odontojenik tümör: 64 vakalık retrospektif çalışma

Keratocystic odontogenic tumor: A retrospective study of 64 cases

Pages
59–64
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Periodic controls and aggressive treatment approach es may be effective in the prevention of recurrences.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: The purpose of this retrospective study was to evaluate the clinicopathological features of 64 patients with keratocystic odontogenic tumor (KCOT).
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Key Findings & Data:Materials and Methods: The patients ranged in age at the time of diagnosis from 8 to 74 years (mean: 38.20 ± 16.71).
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Conclusion & Impact:Periodic controls and aggressive treatment approach es may be effective in the prevention of recurrences.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: The purpose of this retrospective study was to evaluate the clinicopathological features of 64 patients with keratocystic odontogenic tumor (KCOT). Materials and Methods: The patients ranged in age at the time of diagnosis from 8 to 74 years (mean: 38.20 ± 16.71). Postoperative follow-up period was 3-8 years (mean time 4.76 ± 1.10). This research was carried out on panoramic radiographs and histopathological samples. Data such as gender, age, treatment methods, location of the tumor, presence of impacted teeth and its histological features were subjected to descriptive statistical analyses with the statistical software program. Results: Of the 64 analyzed cases of KCOT, 68.8% of them were men and 31.2% were females (male-to-fem ale ratio was 2.2:1 ). It was observed that KCOT peaked in the third an d fifth decade of life (23.4%-20.3%). The incidence of KCOT was higher in the mandible than in the maxilla (76.6%-23.4%). There was recurrence in nine out of 64 subjects (14.1%) in the follow -up period. The recurrence was more often found in posterior mandible. It is noteworthy that in 9 recurren t subjects , 7 lesions were parakeratotic and 4 lesions were associated with daughter cysts. Conclusion: Although there are several studies about KCOT in the literature, the choice of treatment modalities remains controversial. In recurrent subjects, more aggressive therapy approach es should be considered. Periodic controls and aggressive treatment approach es may be effective in the prevention of recurrences.

Özet

Amaç: Bu retrospektif çalışma da, keratokistik odontojenik tümör (KOT) tanısı konmuş 64 hastanın klinikopatolojik özelliklerinin değerlendirilmesi amaçlanmıştır. Gereç ve Yöntem: Hastaların yaş aralığı 8 ile 74 yaş aralığında değişiklik gösteriyordu (ortalama: 38.20±16.71). Postoperatif takip süresi 3 ile 8 yıl arasındaydı (ortalama: 4.76±1.10). Çalışmada panoromik radyografiler ve histopatolojik örnekler değerlendirildi. Cinsiyet, yaş, tedavi yöntemleri, tümörün lokalizasyonu, gömülü diş varlığı ve tümörün histolojik özellikleri gibi veriler istatistiksel yazılım programı yardımı ile tanımlayıcı istatistiksel analizlere tabi tutuldu. Bulgular: 64 KOT vakası incelendiğinde olguların%68.8’ini erkekler % 31.2‘sini ise kadınlar oluşturuyordu (kadın/erkek oranı 1:2.2). KOT’un hayatın üçüncü ve beşinci on yılı içinde pik yaptığı bulundu (%23.4-%20.3). KOT insidansı mandibulada maksillaya oranla daha yüksekti (% 76.6 -% 23.4). Takip sürecinde 64 vakanın 9 tanesinin (%14. 1) nüks ettiği tespit edildi. Nüks vakalarının büyük çoğunluğu posterior mandibulada tespit edildi. Dikkat çekici şekilde 9 nüks vakasının 7’si parakeratotik tipte olup 4 tanesi daughter kist ile ilkişkiliydi. Sonu ç: Literatürde KOT ile ilgili birçok çalışma olmasına rağmen tedavi stratejilerinin seçimi halan tartışmalıdır. Rekürrens gösteren vakalarda daha agresif tedavi yöntemlerin seçimi gerekmektedir. Periodik kontroller ve agresif tedavi yaklaşımları rekürrensin önlenmesinde etkili olabilir.

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Cite This Article

AKAY, C., TETİK, A., ZEYTİNOĞLU, M. (2015). Keratokistik odontojenik tümör: 64 vakalık retrospektif çalışma. Ege Tıp Dergisi, Cilt: 54 - Sayı: 2, 59–64. https://ajindex.com/articles/203399

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References (16)

  1. McIvor M. The radiological features of odontogenic keratocysts. Br J Oral Surg 1972;10(2):116 -25
  2. Pindborg J J, Hans en J. Studies o n o dontogenic c yst e p i thelium
  3. Clinical a nd roentgenologic aspects o f o dontogenic keratocysts. Acta Pathol Microbiol Scand 1963;58(4):283 -94
  4. Maurette PE, Jorge J, de Moraes M. Conservative treatment protocol of odontogenic keratocyst: A preliminary study. J Oral Maxillofac Surg 2006;64(3):379 -83
  5. Chow HT. Odontogenic keratocyst: A clinical experience in Singapore. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1998;86(5):573 -7
  6. Philipsen HP. Keratocystic odontogenic tumour. In: Barnes L, Eweson JW, Reichart P, Sidransky D (eds ). World Health Organization Classification of Tumors. Lyon: IARC Press; 2005: 306 -7
  7. Forssell K, Sorvari TE, Oksala EA. Clinical and radiographic study of odontogenic keratocysts in jaws. Proc Finn Dent Soc 1974;70(4):121 -34
  8. Habi bi A, Saghravanian N, Ha bibi M, Mellati E, Habibi M. Keratocystic odontogenic tumor: A 10 -year retrospective study of 83 cases in an Iranian population. J Oral Sci 2007;49(3):229 -35
  9. Zhao YF, Wei JX, Wang SP. Treatment of odontogenic keratocysts: A follow-up of 255 Chinese patients. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002;94(2):151 -6
  10. Gustafson G, Lindahl B, Dahl E, Svensson A. The nevoid basal cell carcinoma syndrome --Gorlin's syndrome. Multiple jaw cysts and skin cancer. Swed Dent J 1989;13(4):131 -9
  11. Neville BW, Damm DD, Allen CM, Bouquot JE. Oral and M axillofacial Pathology. 2nd ed. Philadelphia: Saunders; 2002: 595
  12. Gorl i n RJ, Vickers RA, Kellen E, W i ll i amson J J. Multi ple b asal -c ell n evi s yndrome. An a nalys i s o f a s yndrome c ons i st i ng o f m ulti ple n evo i d b asal -cell carci noma, jaw cysts, s keletal anomali es, m edulloblastoma, a nd hyporesponsiveness to parathormone. Cancer 1965;18 (2):89 -104
  13. Morgan TA, Burton CC, Qian F. A retrospective review of treatment of the odontogenic keratocyst. J Oral Maxillofac Surg 2005;63(5):635 -9
  14. Barnes L, Eveson JW, Reichart P, Sidransky D. World H ealth Organization Classification of Tumors: Pathology and Genetics of Head and N eck Tumors. Lyon: IARC Press;2005
  15. Thompson L, Goldblum J. Head and N eck P athology: A Volume in the Series Foundations in Diagnostic Pathology. Philadelphia: Elsevier;2006
  16. Kakarantza -Angelopoulou E, Nicolatou O. Odontogenic keratocysts: Clinicopathologic stu