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Journals / Klinik Psikiyatri Dergisi / 2016 / Cilt: 19 - Sayı: 4

Evaluation of neurocognitive deficits in obsessive compulsive disorder with Adas-cog: A comparative study with the healthy control group

Obsesif Kompulsif Bozuklukta bilişsel işlevlerin Adas-Cog ölçeği ile değerlendirilmesi: Sağlıklı kontrol grubuyla karşılaştyrmalı bir çalyşma

Ayşe DÖNDÜ
ÇAĞDAŞ ÖYKÜ MEMİŞ
LEVENT SEVİNÇOK
Pages
156–166
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Furtherstudies in larger samples of OCD patients are needed toassess the availability of ADAS-Cog in measuring theneurocognitive impairments

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Obsessive compulsive disorder (OCD) is characterized by recurrent intrusive thoughts and repetitivebehaviors or mental acts compulsions.
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Key Findings & Data:Method: Thirty twopatients with a diagnosis of OCD and twenty six healthycontrols were administrated Structured Clinical Interviewfor DSM Disorders (SCID-I), Yale Brown ObsessiveCompulsive Scale (Y-BOKS), ADAS-Cog Scale, MiniMental Status Examination (MMSE), HamiltonDepression Rating Scale (HDRS) and Hamilton AnxietyRating Scales (HARS).
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Conclusion & Impact:Furtherstudies in larger samples of OCD patients are needed toassess the availability of ADAS-Cog in measuring theneurocognitive impairments
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Obsessive compulsive disorder (OCD) is characterized by recurrent intrusive thoughts and repetitivebehaviors or mental acts compulsions. Previous studiesobviously indicate that OCD patients have several impairments in memory and other neurocognitive functions.Our primary aim is to assess the cognitive impairment inOCD patients through Alzheimer's Disease AssessmentScale Cognitive Subscale (ADAS-Cog) which is widelyused in Alzheimer's Dementia. Method: Thirty twopatients with a diagnosis of OCD and twenty six healthycontrols were administrated Structured Clinical Interviewfor DSM Disorders (SCID-I), Yale Brown ObsessiveCompulsive Scale (Y-BOKS), ADAS-Cog Scale, MiniMental Status Examination (MMSE), HamiltonDepression Rating Scale (HDRS) and Hamilton AnxietyRating Scales (HARS). Results: When we compared twogroups, OCD subjects performed significantly worse inthe fields of ADAS-Cog Total (p<0.0001), Word Recall(p<0.0001), Word Recognition (p<0.0001) Commands(p<0.0001), Constructional Praxis (p<0.05) andOrientation (p<0.05) Tests of ADAS-Cog compared tothe healthy control group. Conclusion: We suggest thatADAS-Cog might be used as an available tool to assesssome neurocognitive deficits in OCD patients. Furtherstudies in larger samples of OCD patients are needed toassess the availability of ADAS-Cog in measuring theneurocognitive impairments

Özet

Amaç: Obsesif Kompulsif Bozukluk (OKB) yineleyici vesürekli dü?ünceler ile tekrarlanan davrany?larla karakterizedir. Önceki çaly?malarda OKB hastalarynda bellek vedi?er nörokognitif i?levlerde sorunlaryn oldu?u saptanmy?tyr. Çaly?mamyzdaki amacymyz OKB hastalaryndaki bili?sel i?lev bozukluklaryny Alzheimer hastalarynda kullanylan Alzheimer Hastaly?y De?erlendirme ölçe?i-Bili?selAlt ölçe?i (Adas-Cog) ile belirlemeye çaly?maktyr. Gereçve Yöntem: Çaly?maya DSM-IV tany ölçütlerine göre OKBtanysy alan 32 hasta ile 26 sa?lykly kontrol alynmy?tyr.Olgulara Yale-Brown Obsesyon-Kompulsiyon Ölçe?i (YBOKÖ), Yapylandyrylmy? Klinik Görü?me (SCID-I), ADAScog ve Mini Mental Durum Yncelemesi Testi (MMDM),Depresyon ve anksiyete ?iddetini belirlemek içinHamilton Depresyon De?erlendirme Ölçe?i (HDDÖ) veHamilton Anksiyete De?erlendirme (HADÖ) ölçekleriuygulanmy?tyr. Bulgular: ADAS-Cog toplam ve alt maddeskorlary iki grup arasynda kar?yla?tyryldy?ynda, ADAS-COGtoplam (p<0.0001), kelime hatyrlama (p<0.0001),kelime tanyma (p<0.0001), komutlar (p<0.0001), konstrüksiyonel praksi (p<0.05), oryantasyon (p<0.05) altölçek skorlarynyn OKB grubunda kontrol grubuna göreanlamly derecede kötü oldu?u bulunmu?tur. Sonuç:ADAS-Cog OKB hastalaryndaki bazy nörobili?sel kusurlaryölçmede uygun bir araç olarak kullanylabilir. Klinik pratikte OKB hastalaryndaki bili?sel sorunlaryny saptamadaAdas-Cog'un kullanylmasy ile ilgili daha kapsamly ileriyedönük çaly?malara ihtiyaç vardyr

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Cite This Article

DÖNDÜ, A., MEMİŞ, Ç. Ö., SEVİNÇOK, L. (2016). Evaluation of neurocognitive deficits in obsessive compulsive disorder with Adas-cog: A comparative study with the healthy control group. Klinik Psikiyatri Dergisi, Cilt: 19 - Sayı: 4, 156–166. https://ajindex.com/articles/202678

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