Journals / Turkish Journal of Zoology / 2020 / Cilt: 44 - Sayı: 6

Order Diptera as a model in the studies of insect immunity: a review

Pages
481–489
Publication Date
2020-11-20
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The current review demonstrates that the studies conducted on dipteran species concern all existing mechanisms of immune defense, namely antimicrobial peptides, signaling pathways, pathogen recognition, the different types of hemocytes, antiviral and other immune responses (phagocytosis, nodulation, melanization and encapsulation).

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Order Diptera is the most important group of animals when it comes to insect immunity research.
📊
Key Findings & Data:Other crucial representatives are those of the mosquito group, as they are vectors of a number of infectious diseases infecting higher vertebrates and humans.
💡
Conclusion & Impact:The current review demonstrates that the studies conducted on dipteran species concern all existing mechanisms of immune defense, namely antimicrobial peptides, signaling pathways, pathogen recognition, the different types of hemocytes, antiviral and other immune responses (phagocytosis, nodulation, melanization and encapsulation).
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Dipterans · antimicrobial peptides · immune responses

Abstract

Order Diptera is the most important group of animals when it comes to insect immunity research. The largest share of experimental data in the group falls on the genus Drosophila - a model species with a number of advantages. Other crucial representatives are those of the mosquito group, as they are vectors of a number of infectious diseases infecting higher vertebrates and humans. As representatives of the genera, Anopheles, Aedes and Culex are very significant model organisms. In total, more than 40 dipteran species are being actively studied as models in various aspects related to immunity. Together with the representatives of the order Lepidoptera, they are the major source of the knowledge gained so far on the defense mechanisms in insects. The current review demonstrates that the studies conducted on dipteran species concern all existing mechanisms of immune defense, namely antimicrobial peptides, signaling pathways, pathogen recognition, the different types of hemocytes, antiviral and other immune responses (phagocytosis, nodulation, melanization and encapsulation).

🔖

Cite This Article

TAKOV, D. I., OSTOİCH, P. V., TCHORBANOV, A. I., PİLARSKA, D. K. (2020). Order Diptera as a model in the studies of insect immunity: a review. Turkish Journal of Zoology, Cilt: 44 - Sayı: 6, 481–489. https://ajindex.com/articles/200185

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (2)

  1. Adams MD, 2000,
  2. SCIENCE, V287, P2185, DOI 10.1126/science.287.5461.2185 Adang MJ, 2020, PREPRINT RES SQUARE. Ashburner M, 2005, DROSOPHILA LAB HDB, P1285 Barillas-Mury C, 1999, EMBO J, V18, P959, DOI 10.1093/emboj/18.4.959 BarillasMury C, 1996, EMBO J, V15, P4691, DOI 10.1002/j.1460-2075.1996.tb00846.x Bartholomay LC, 2004, INFECT IMMUN, V72, P4114, DOI 10.1128/IAI.72.7.4114-4126.2004 Beck ET, 2007, INSECT BIOCHEM MOLEC, V37, P1222, DOI 10.1016/j.ibmb.2007.07.015 Beckage NE, 2008, INSECT IMMUNOLOGY, P1. Bian G, 2005, P NATL ACAD SCI USA, V102, P13568, DOI 10.1073/pnas.0502815102 Blandin S, 2002, EMBO REP, V3, P852, DOI 10.1093/embo-reports/kvf180 Blitvich BJ, 2002, INSECT MOL BIOL, V11, P431, DOI 10.1046/j.1365-2583.2002.00352.x Boulanger N, 2004, INFECT IMMUN, V72, P7140, DOI 10.1128/IAI.72.12.7140-7146.2004 CARTER JB, 1987, J MORPHOL, V191, P289, DOI 10.1002/jmor.1051910308 Castillo JC, 2006, INSECT BIOCHEM MOLEC, V36, P891, DOI 10.1016/j.ibmb.2006.08.010 Chase MR, 2000, INSECT BIOCHEM MOLEC, V30, P953, DOI 10.1016/S0965-1748(00)00068-0 Christophides GK, 2004, IMMUNOL REV, V198, P127, DOI 10.1111/j.0105-2896.2004.0127.x Crowley LD, 2002, J MED ENTOMOL, V39, P931, DOI 10.1603/0022-2585-39.6.931 De Gregorio E, 2002, EMBO J, V21, P2568, DOI 10.1093/emboj/21.11.2568 DIMARCQ JL, 1986, DEV COMP IMMUNOL, V10, P626 DIMARCQ JL, 1990, EMBO J, V9, P2507, DOI 10.1002/j.1460-2075.1990.tb07430.x DIMARCQ JL, 1988, EUR J BIOCHEM, V171, P17, DOI 10.1111/j.1432-1033.1988.tb13752.x Dimopoulos G, 1997, P NATL ACAD SCI USA, V94, P11508, DOI 10.1073/pnas.94.21.11508 DOMNAS A, 1974, J INVERTEBR PATHOL, V24, P293, DOI 10.1016/0022-2011(74)90137-2 Dong SZ, 2020, PLOS PATHOG, V16, DOI 10.1371/journal.ppat.1008453 Dong YM, 2009, J BIOL CHEM, V284, P9835, DOI 10.1074/jbc.M807084200 Dostert C, 2005, NAT IMMUNOL, V6, P946, DOI 10.1038/ni1237 DRIF L, 1983, DEV COMP IMMUNOL, V7, P687, DOI 10.1016/0145-305X(83)90094-0 Drolet BS, 2005, J MED ENTOMOL, V42, P409, DOI 10.1603/0022-2585(2005)042[0409:VCOCSD]2.0.CO;2 Escalona-Vargas D, 2016, IEEE ENG MED BIO, P904, DOI 10.1109/EMBC.2016.7590847 Foley DA, 1978, COMP PATHOBIOLOGY, P114. FORTON KF, 1985, J PARASITOL, V71, P331, DOI 10.2307/3282015 Franchini A, 1996, TISSUE CELL, V28, P587, DOI 10.1016/S0040-8166(96)80061-9 Franssens V, 2005, ARCH INSECT BIOCHEM, V59, P32, DOI 10.1002/arch.20053 Fu X, 2017, SCI REP, V7, P1. Galiana-Arnoux D, 2006, NAT IMMUNOL, V7, P590, DOI 10.1038/ni1335 Girard YA, 2005, J MED ENTOMOL, V42, P429, DOI 10.1603