We present a case of a SIH with Chiari I malformation accompanied by an unusual clinical presentation of persistent hypoglycemia.
📌 3 Key Takeaways
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Objective & Hypothesis:Spontaneous intracranial hypotension (SIH) is a rare and potentially serious condition in childhood.
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Key Findings & Data:Cerebrospinal fluid (CSF) volume depletion is thought to be the main causative feature for intracranial hypotension and results from a spontaneous CSF leak, often at the spine level.
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Conclusion & Impact:We present a case of a SIH with Chiari I malformation accompanied by an unusual clinical presentation of persistent hypoglycemia.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Özet
Spontaneous intracranial hypotension (SIH) is a rare and potentially serious condition in childhood. Cerebrospinal fluid (CSF) volume depletion is thought to be the main causative feature for intracranial hypotension and results from a spontaneous CSF leak, often at the spine level. SIH is increasingly diagnosed in clinical practice, although it manifests a varied symptomatology. The downward displacement of the brain, sometimes mimicking a Chiari I malformation, has rarely been reported. We present a case of a SIH with Chiari I malformation accompanied by an unusual clinical presentation of persistent hypoglycemia.
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Cite This Article
ÖNAL, H., ERSEN, A., GEMİCİ, H., ADAL, E., GÜLER, S., SANDER, S., ALBAYRAM, S. (2018). Acquired Chiari I Malformation Secondary to Spontaneous Intracranial Hypotension Syndrome and Persistent Hypoglycemia: A Case Report. Journal of Clinical Research in Pediatric Endocrinology, Cilt: 10 - Sayı: 4, 391–394. https://ajindex.com/articles/199912
Schievink WI, Dodick DW, Mokri B, Silberstein S, Bousser MG, Goadsby PJ. Diagnostic criteria for headache due to spontaneous intracranial hypotension: a perspective. Headache 2011;51:1442-1444. Epub 2011 Jun 9 Limaye K, Samant R, Lee RW. Spontaneous intracranial hypotension: diagnosis to management. Acta Neurol Belg 2016;116:119-125. Epub 2015 Dec 10 Mokri B. Spontaneous Intracranial Hypotension. Continuum (Minneap Minn) 2015;21:1086-1108.
Elster AD, Chen MY. Chiari I malformations: clinical and radiologic reappraisal. Radiology 1992;183:347-353.
Atkinson JL, Weinshenker BG, Miller GM, Piepgras DG, Mokri B. Acquired Chiari I malformation secondary to spontaneous spinal cerebrospinal fluid leakage and chronic intracranial hypotension syndrome in seven cases. J Neurosurg 1998;88:237-242.
Mokri B, Hunter SF, Atkinson JL, Piepgras DG. Orthostatic headaches caused by CSF leak but with normal CSF pressures. Neurology 1998;51:786-790.
Rekate HL, Nadkarni TD, Teaford PA, Wallace D. Brainstem dysfunction in Chiari malformation presenting as profound hypoglycemia: presentation of four cases, review of the literature, and conjecture as to mechanism. Neurosurgery 1999;45:386-391.
Tarani L, Del Balzo F, Costantino F, Properzi E, D’Eufemia P, Liberati N, Spalice A. Chiari type I malformation, syncope, headache, hypoglycemia and hepatic steatosis in an 8-year old girl: a causal association? Pediatr Rep 2010;2:8. Brightbill TC, Goodwin RS, Ford RG. Magnetic resonance imaging of intracranial hypotension syndrome with pathophysiological correlation. Headache 2000;40:292-299.
Teff KL, Levin BE, Engelman K. Oral sensory stimulation in men: effects on insulin, C-peptide, and catecholamines. Am J Physiol 1993;265:1223-1230. Shimazu T. Regulation of glycogen metabolism in liver by the autonomic nervous system V. activation of glycogen synthetase by vagal stimulation. Biochim Biophys Acta 1971;252:28-38. Ahren B