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Journals / GORM:Gynecology Obstetrics & Reproductive Medicine / 2014 / Cilt: 20 - Sayı: 3

Cooper T ve Levonorgestrelli rahim içi araçların servikal mukus proteoglikan yapısı üzerine etkilerinin karşılaştırılması

Comparison of the effects of copper T and Levonorgestrel IUD on proteoglycan composition of cervical mucus

YEŞİM BAYOĞLU TEKİN
Emine Seda GÜVEN GÜVENDAĞ
Zihni Açar YAZICI
Aynur KIRBAŞ
Figen ŞAHİN KIR
Pages
159–162
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

CONCLUSION: Copper T and Levonorgestrel intrauterine contraceptive devices have significant effects on proteoglycan component of cervical mucus.

📌 3 Key Takeaways

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Objective & Hypothesis:OBJECTIVE: The aim of this study was to determine the effects of Copper T and Levonorgestrel IUD (LNG-IUD) on the proteoglycan composition of cervical mucus.
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Key Findings & Data:The study participants were between 18-50 years old, using either Copper T or LNG-IUD for contraception.
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Conclusion & Impact:CONCLUSION: Copper T and Levonorgestrel intrauterine contraceptive devices have significant effects on proteoglycan component of cervical mucus.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

OBJECTIVE: The aim of this study was to determine the effects of Copper T and Levonorgestrel IUD (LNG-IUD) on the proteoglycan composition of cervical mucus. STUDY DESIGN: This was a cross-sectional study that was conducted at a gynecology outpatient clinic of a University hospital for a six month period. The study participants were between 18-50 years old, using either Copper T or LNG-IUD for contraception. Cervical mucus samples were collected 7 days after the menstrual bleeding and the levels of hyaluronan (HA), heparin sulfate (HS) and sulfated-gly- cosaminoglycans (s-GAG) were evaluated. RESULTS: The levels of HA, HS and s-GAG in the Copper-T and LNG-IUD groups were higher than those of the controls. However, the difference was statistically significant only for s-GAG (p<0.001). CONCLUSION: Copper T and Levonorgestrel intrauterine contraceptive devices have significant effects on proteoglycan component of cervical mucus.

Özet

AMAÇ: Bu çalışmanın amacı Cooper T ve Levonorgestrelli Rahim içi araçların (LNG-IUD) servikal mukus proteoglikan yapısı üzerine etkisinin değerlendirilmesidir. GEREÇ VE YÖNTEM: Bu kesitsel çalışma bir üniversite hastanesi jinekoloji polikliniğinde altı ay süre ile yürütülmüştür. Dahil edilme kriterleri 18-50 yaş arasında olmak ve kontraseptif yöntem olarak Copper T ya da LNG-IUD kullanmaktır. Mu kus örnekleri menstural kanamadan 7 gün sonra elde edilmiş ve servikal mukusta Hyaluronan (HA), Heparin Sulfat (HS) ve sulfatlanmış glikozaminoglikan (s-GAG) seviyeleri değerlendirilmiştir. BULGULAR: Copper T ve LNG-IUD gruplarında HA, HS ve s- GAG seviyeleri kontrol grubundan daha yüksektir. Ancak fark sadece s-GAG için istatistiksel olarak anlamlıdır (p<0,001). SONUÇ: Bakırlı ve levonorgestrelli rahim içi kontraseptif araçların servikal mukusun proteoglikan içeriği üzerinde önemli etkileri vardır.

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Cite This Article

TEKİN, Y. B., GÜVENDAĞ, E. S. G., YAZICI, Z. A., KIRBAŞ, A., KIR, F. Ş. (2014). Cooper T ve Levonorgestrelli rahim içi araçların servikal mukus proteoglikan yapısı üzerine etkilerinin karşılaştırılması. GORM:Gynecology Obstetrics & Reproductive Medicine, Cilt: 20 - Sayı: 3, 159–162. https://ajindex.com/articles/199781

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