Journals / Cukurova Medical Journal / 2021 / Cilt: 46 - Sayı: 2

Etiologic agents of acute gastroenteritis in adults

Erişkin akut gastroenterit olgularında etiyolojik ajanlar

Pages
654–662
Publication Date
2021-06-30
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

It is concluded that no antibiotic is needed for more than 65% of adult patients with AGE.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: The aim of this study was to determine the etiological factors in adult cases with acute gastroenteritis (AGE).
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Key Findings & Data:Materials and Methods: In this study, bacteriological, parasitological and virological examinations were performed on the stool samples of 110 patients, admitted in a 7-month period with a diagnosis of acute gastroenteritis with a daily stool frequency of more than three and symptoms of less than 14 days, were evaluated.
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Conclusion & Impact:It is concluded that no antibiotic is needed for more than 65% of adult patients with AGE.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:gastroenteritis · diarrhea · etiology

Abstract

Purpose: The aim of this study was to determine the etiological factors in adult cases with acute gastroenteritis (AGE). Materials and Methods: In this study, bacteriological, parasitological and virological examinations were performed on the stool samples of 110 patients, admitted in a 7-month period with a diagnosis of acute gastroenteritis with a daily stool frequency of more than three and symptoms of less than 14 days, were evaluated. Toxin A of Clostridium difficile was investigated in the stools of patients who have taken antibiotics in the last 10 days. Results: Of the 110 patients with acute gastroenteritis, 59 (53.6%) were male, and the mean age was 36 (± 14). At least one pathogen was detected as an acute gastroenteritis agent in 44.5% of the patients (n = 49), but no pathogen was identified in 55.5% of them. The detected pathogens were as follows: Entamoeba histolytica (11.8%), Shigella spp. (10.9%), rotavirus (10,9%), Giardia intestinalis (5.4%), Salmonella spp. (2.7%), Candida spp. (2.7%), enteropathogenic Escherichia coli (0.9%), Blastocystis hominis (0.9%), and Clostridium difficile (0.9%). More than one pathogen was detected in three patients (2.7%). Among Shigella spp. (n=12), Shigella sonnei (n = 6), Shigella flexneri (n = 4) and Shigella boydii (n = 2); and among Salmonella spp. (n=3) Salmonella enteritidis (n = 2) and Salmonella arizonae (n = 1) were identified. Conclusion: In this study, pathogens were identified in 44.5% of stool samples of the patients with AGE. The most common pathogens identified in etiology are protozoa (18.1%), bacteria (15.5%), mainly Shigella spp., and rotavirus (10.9%). It is concluded that no antibiotic is needed for more than 65% of adult patients with AGE.

Özet

Amaç: Bu çalışmada akut gastroenteritler (AGE) nedeniyle başvuran erişkinlerin dışkı örneklerinde etiyolojik etkenlerin belirlenmesi amaçlanmıştır. Gereç ve Yöntem: Bu çalışmada, 7 aylık dönemde, günlük dışkı sıklığı 3 üzerinde olan ve belirtileri 14 günden kısa süren ve akut gastroenterit tanısıyla izlenen 110 erişkin hastanın dışkı örneklerinde bakteriyolojik, parazitolojik ve virolojik incelemeler yapılmıştır. Son 10 gün içinde antibiyotik kullanmış hastaların dışkılarında Clostridium difficile’ye ait Toksin A araştırılmıştır. Bulgular: Akut gastroenteritli 110 olgunun 59’u (%53,6) erkek, yaş ortalaması 36 (±14) idi. Hastaların %44,5’inde (n=49) akut gastroenterit etkeni olarak en az bir patojen saptanmış, ancak %55,5’inde herhangi bir etken gösterilememiştir. Dışkı örneklerinde saptanan etkenler sıklığa göre Entamoeba histolytica (%11,8), Shigella türleri (%10,9), rotavirus (%10,9), Giardia intestinalis (%5,4), Salmonella türleri (%2,7), Candida türleri (%2,7), enteropatojenik Escherichia coli (%0,9), Blastocystis hominis (%0,9), Clostridium difficile (%0,9) olarak sıralanmıştır. Hastaların üçünde (%2,7) birden fazla patojen tespit edilmiştir. Shigella türleri (n=12) arasında Shigella sonnei (n=6), Shigella flexneri (n=4) ve Shigella boydii (n=2), Salmonella türleri arasında Salmonella enteritidis (n=2) ve Salmonella arizonae (n=1) belirlenmiştir. Sonuç: Bu çalışmada AGE olgularının dışkı örneklerinin %44,5’inde patojen saptanmıştır. Etiyolojide en sık protozoa (%18,1), başta Shigella türleri olmak üzere bakteriler (%15,5) ve rotavirus (%10,9) belirlenmiştir. Erişkin AGE olgularının %65’inden daha büyük bölümünde tedavide antibiyotik gerekmediği kanaatine varılmıştır.

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Cite This Article

İNAL, A. S., KİBAR, F., YAMAN, A., TAŞOVA, Y. (2021). Etiologic agents of acute gastroenteritis in adults. Cukurova Medical Journal, Cilt: 46 - Sayı: 2, 654–662. https://ajindex.com/articles/199388

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