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Journals / Turkish Journal of Medical Sciences / 2015 / Cilt: 45 - Sayı: 5

A comparison of hair and serum trace elements in patients with Alzheimer disease and healthy participants

EMİNE RABİA KOÇ
ATİLLA İLHAN
ZÜBEYDE AYTÜRK
BURCU ACAR
MUKADDES GÜRLER
AYNUR ALTUNTAŞ
MUSTAFA KARAPİRLİ
ABDURRAHMAN SAİD BODUR
Pages
1034–1039
Publication Date
2015-12-04
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Due to the more permanent status, the analysis of these element levels in hair might be superior to blood analysis.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Background/aim: To determine whether there was a difference between serum and hair trace elements' concentrations in patients with Alzheimer disease (AD) and healthy participants.
📊
Key Findings & Data:Results: The mean hair selenium and zinc levels of patients with AD were significantly lower than the levels found for control participants (P < 0.05).
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Conclusion & Impact:Due to the more permanent status, the analysis of these element levels in hair might be superior to blood analysis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Alzheimer disease · trace element · hair

Abstract

Background/aim: To determine whether there was a difference between serum and hair trace elements' concentrations in patients with Alzheimer disease (AD) and healthy participants. Materials and methods: Hair and serum copper, selenium, zinc, magnesium, manganese, and iron levels were measured by inductively coupled plasma-mass spectrometry in patients with AD and healthy participants, and the obtained results were statistically compared. Results: The mean hair selenium and zinc levels of patients with AD were significantly lower than the levels found for control participants (P < 0.05). Patients with AD had significantly higher mean hair copper and manganese levels than the controls. There were no significant differences between AD patients and controls with respect to the hair iron and magnesium levels (P > 0.05). Hair and serum trace element (copper, selenium, zinc, magnesium, manganese, and iron) levels in patients with AD showed no significant difference according to mini mental test scores or sex (P > 0.05). Conclusion: Some trace element levels may change in patients with AD. Due to the more permanent status, the analysis of these element levels in hair might be superior to blood analysis.

Özet

Background/aim: To determine whether there was a difference between serum and hair trace elements' concentrations in patients with Alzheimer disease (AD) and healthy participants. Materials and methods: Hair and serum copper, selenium, zinc, magnesium, manganese, and iron levels were measured by inductively coupled plasma-mass spectrometry in patients with AD and healthy participants, and the obtained results were statistically compared. Results: The mean hair selenium and zinc levels of patients with AD were significantly lower than the levels found for control participants (P < 0.05). Patients with AD had significantly higher mean hair copper and manganese levels than the controls. There were no significant differences between AD patients and controls with respect to the hair iron and magnesium levels (P > 0.05). Hair and serum trace element (copper, selenium, zinc, magnesium, manganese, and iron) levels in patients with AD showed no significant difference according to mini mental test scores or sex (P > 0.05). Conclusion: Some trace element levels may change in patients with AD. Due to the more permanent status, the analysis of these element levels in hair might be superior to blood analysis.

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Cite This Article

KOÇ, E. R., İLHAN, A., AYTÜRK, Z., ACAR, B., GÜRLER, M., ALTUNTAŞ, A., KARAPİRLİ, M., BODUR, A. S. (2015). A comparison of hair and serum trace elements in patients with Alzheimer disease and healthy participants. Turkish Journal of Medical Sciences, Cilt: 45 - Sayı: 5, 1034–1039. https://ajindex.com/articles/198431

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