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Journals / GORM:Gynecology Obstetrics & Reproductive Medicine / 2015 / Cilt: 21 - Sayı: 1

İkinci Trimester Amniyon Sıvısı β2- Mikroglobulin Değerleri

Amniotic Fluid β2- Microglobulin Measurements

Emine AYDIN
Tuna Alp BEKSAÇ
Ergun KARAAĞAOĞLU
MEHMET SİNAN BEKSAÇ
Pages
1–3
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Keywords: Amniotic fluid, β2-microglobulin, Second trimester

📌 3 Key Takeaways

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Objective & Hypothesis:OBJECTIVE: To determine β2-microglobulin levels in amniotic fluid during the course of second trimester.
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Key Findings & Data:STUDY DESIGN: One hundred patient’s amniotic fluid β2-microglobulin levels had been evaluated ret- rospectively (March-October 2009).
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Conclusion & Impact:Keywords: Amniotic fluid, β2-microglobulin, Second trimester
🔬Design:Research Article
📍Scope:2009 Verileri
⚙️Variables:Domain Parameters

Abstract

OBJECTIVE: To determine β2-microglobulin levels in amniotic fluid during the course of second trimester. STUDY DESIGN: One hundred patient’s amniotic fluid β2-microglobulin levels had been evaluated ret- rospectively (March-October 2009). The most common amniocentesis indication was advanced mater- nal age (33.3%). Others were; high risk result for triple test (18.5%), high risk result for double test (6.48%), ventriculomegaly (5.55%), obstetric history for fetus with down syndrome (4.62%), the pres- ence of soft markers on ultrasound (13.8%), others (17.8%). Patients average gravida was 2.66 (range: 1-6), parity was 0.75 (range: 0-3), abortion was 0.65 (range: 0-3). RESULTS: All patients were at second trimester and the average gestational week was 17.7 (range 15- 22). Patients were divided into four groups (15th, 16th, 17-18th and 19-20th gestational weeks). We have demonstrated that amniotic fluid β2-microglobulin levels are increased progressively throughout the sec- ond trimester. We have specified normal β2-microglobulin values of each gestational week/period in order to be used in clinical practice. CONCLUSION: We have demonstrated that amnionic fluid β2-microglobulin levels are increased pro- gressively throughout the second trimester. Keywords: Amniotic fluid, β2-microglobulin, Second trimester

Özet

AMAÇ: İkinci trimester sırasında amniyotik sıvıda β2-mikrog- lobulin düzeylerini belirlemek. GEREÇ VE YÖNTEMLER: Bu çalışmada, 100 hastanın amni- yotik sıvı β2-mikroglobulin düzeyleri retrospektif olarak değer- lendirildi (Mart 2009 - Ekim 2009). En sık amniyosentez endi- kasyonu ileri anne yaşı olup (%33,3), diğerleri sırasıyla üçlü test risk artışı (%18,5), ikili test risk artşı (%6,48), ventrikülo- megali (%5,55), down sendromlu çocuk öyküsü (%4,62), di- ğerleri (%17,8) idi. Ortalama gebelik sayısı 2,66 parite 0,75, abortus 0,65 idi. BULGULAR: Tüm hastalar ikinci trimestırda olup, ortalama gebelik haftası 17,65 (15-22) idi. Hastalar dört gruba ayrıldı (15 (n=7), 16 (n=31), 17-18 (n=45) ve 19-20. (n=14) gestasyonel haftalar). Bu çalışmada ikinci trimestırda haftalar ilerledikçe amniyotik sıvı β2-mikroglobulin düzeylerinin yükseldiğini gös- terdik. Aynı zamanda klinik pratikte kullanılmak üzere, her ges- tasyonel haftanın amniyotik sıvı β2-mikroglobulin düzeyini be- lirledik. SONUÇ: Bu çalışmada ikinci trimestırda haftalar ilerledikçe amniyotik sıvı β2-mikroglobulin düzeylerinin yükseldiği göste- rilmiştir.

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Cite This Article

AYDIN, E., BEKSAÇ, T. A., KARAAĞAOĞLU, E., BEKSAÇ, M. S. (2015). İkinci Trimester Amniyon Sıvısı β2- Mikroglobulin Değerleri. GORM:Gynecology Obstetrics & Reproductive Medicine, Cilt: 21 - Sayı: 1, 1–3. https://ajindex.com/articles/198357

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