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Journals / Eskişehir Technical University Journal of Science and Technology A - Applied Sciences and Engineering / 2016 / Cilt: 17 - Sayı: 2

DETERMINATION AND EVALUATION OF ACIDITY CONSTANTS OF SOME IMIDAZOLE AND THIAZOLE LINKED ACETAMIDE COMPOUNDS

Funda TAY
Murat DURAN
Cihan İSPİR
Şeref DEMİRAYAK
Pages
263–272
Publication Date
2016-07-14
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The second protonation was observed to occur on the nitrogen atom of the thiazole ring.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:In this work, the effect of substituents on the acidity constants of some acetamide derivatives was investigated.
📊
Key Findings & Data:The acidity constants of nine acetamide derivatives were determined at 25 °C using a UV spectrophotometric method.
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Conclusion & Impact:The second protonation was observed to occur on the nitrogen atom of the thiazole ring.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:İmidazol · Tiyazol · Asetamit

Abstract

In this work, the effect of substituents on the acidity constants of some acetamide derivatives was investigated. The acidity constants of nine acetamide derivatives were determined at 25 °C using a UV spectrophotometric method. When the molecules possessed different substituents the values of the acidity constants changed from 6.01 to 8.22 for the first protonation and from 3.07 to 4.73 for the second protonation. The first protonation under these circumstances was observed to occur on the nitrogen atom of the 2-mercaptoimidazole ring. The second protonation was observed to occur on the nitrogen atom of the thiazole ring.

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Cite This Article

TAY, F., DURAN, M., İSPİR, C., DEMİRAYAK, Ş. (2016). DETERMINATION AND EVALUATION OF ACIDITY CONSTANTS OF SOME IMIDAZOLE AND THIAZOLE LINKED ACETAMIDE COMPOUNDS. Eskişehir Technical University Journal of Science and Technology A - Applied Sciences and Engineering, Cilt: 17 - Sayı: 2, 263–272. https://ajindex.com/articles/196813

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