Journals / Food and Health / 2018 / Cilt: 4 - Sayı: 4

IMMUNOTHERAPY AND POTENTIAL USE OF PROPOLIS IN CANCER IMMUNOTHERAPY

İMMÜNOTERAPİ VE PROPOLİSİN KANSER İMMÜNOTERAPİSİNDE KULLANIM POTANSİYELİ

Pages
231–246
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review, it is aimed to give information about immunotherapy and the use of propolis in cancer immunotherapy.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:In recent years cancer incidence has increased.
📊
Key Findings & Data:Immunotherapy is the treatment of the disease with therapeutic agents that increase or decrease immune responses.
💡
Conclusion & Impact:In this review, it is aimed to give information about immunotherapy and the use of propolis in cancer immunotherapy.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

In recent years cancer incidence has increased. Innovative studies have been carried out on the treatment methods of cancer, a major threat to public health. Immunotherapy is the treatment of the disease with therapeutic agents that increase or decrease immune responses. Immunotherapy is known to be effective in the treatment of cancer. A bee product, propolis that has been investigated for its availability in this respect draws attention because of its antitumor effects. In addition, immunomodulatory effects of propolis, which is known to have antibacterial, antimicrobial, antifungal, antiviral and cytotoxic effects, have been investigated in recent years. According to researchers, propolis is a promising compound in cancer immunotherapy. In this review, it is aimed to give information about immunotherapy and the use of propolis in cancer immunotherapy.

Özet

Son yıllarda kanser hastalığı oldukça yaygın olarak görülmektedir. Halk sağlığı için büyük tehlike oluşturan kanser hastalığının tedavi yöntemleri üzerinde yenilikçi araştırmalar yapılmaktadır. İmmünoterapi immün yanıtları artıran veya azaltan terapötik ajanlar ile ortaya çıkan hastalığın tedavisidir. İmmünoterapinin kanser tedavisinde etkili olduğu bilinmektedir. Bu amaç doğrultusunda kullanılabilirliği araştırılan, bir arı ürünü olan propolis antitümör etkiler göstermesi ile dikkat çekmektedir. Bunun yanı sıra antibakteriyel, antimikrobiyal, antifungal, antiviral ve sitotoksik etkileri olduğu bilinmekte olan propolisin son yıllarda immünomodülatör etkileri incelenmektedir. Araştırmacılara göre propolis kanser immünoterapisinde umut vadeden bir bileşendir. Bu derlemede immünoterapi ve propolisin kanser immünoterapisinde kullanımı hakkında bilgi verilmesi amaçlanmaktadır

🔖

Cite This Article

ONUR, E., NALBANTSOY, A., KIŞLA, D. (2018). IMMUNOTHERAPY AND POTENTIAL USE OF PROPOLIS IN CANCER IMMUNOTHERAPY. Food and Health, Cilt: 4 - Sayı: 4, 231–246. https://ajindex.com/articles/192581

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Akramiené, D., Kondrotas, A., Didžiapetriené, J., Kévelaitis, E. (2007). Effects of β-glucans on the Immune System. Medicisa (Kaunas), 43(8), 597-606.
  2. Arda, M., Minbay, A., Aydın, N., Akay, Ö., İzgür, M., Diker, S. (1998). İmmunoloji. Ankara: Medisan Yayınevi, p. 20-31.
  3. Atayoğlu, T. (2012). Apiterapi Açısından Arı Ürünlerinin Kalite Kriterleri ve Standardizasyonu. Standard Ekonomik ve Teknik Dergi, 601, 68-73.
  4. Awale, S., Li, F., Onozuku, H., Esumi, H., Tezuka, Y., Kadota, S. (2008). Constituents of Brazilian red propolis and their preferential cytotoxic activity against human pancreatic PANC-1 cancer cell line in nutrient-deprived condition. Bioorganic and Medicinal Chemistry, 16, 181-189.
  5. Bankova, V. (2005). Recent trends and important developments in propolis research. Evidence-based Complementary and Alternative Medicine, 2, 29-32.
  6. Banskota, A. H., Tezuka, Y., Kadota, S. (2001). Recent progress in pharmacological research of propolis. Phytotherapy Research,, 15, 561-571.
  7. Barbaros, B., Dikmen, M. (2015). Kanser İmmünoterapisi. Erciyes Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 31(4), 177-181.
  8. Barnes, S. (1997). The chemopreventive properties of soy isoflavonoids in animal models of breast cancer. Breast Cancer Research Treament (46), 169–179.
  9. Bazo, A.P., Rodrigues, M.A.M., Sforcin, J.M., Camargo, J.L.V., Ribeiro, L.R., Salvadori, D.M.F. (2002). Protective action of propolis on the rat colon carcinogenesis. Teratogenesis, Carcinogenesis and Mutagenesis, 22, 183-194.
  10. Boudourova-Krasteva, G., Bankova, V., Sforcin, J. M., Nikolova, N., Popov, S. (1997). Phenolics from Brazilian propolis. Zeitschrift für Naturforschung 52, 676-679.
  11. Burdock, G.A. (1998). Review of the biological properties and toxicity of bee propolis (propolis). Food and Chemical Toxicology, 36, 347–363.
  12. Carvalho, A.A., Finger, D., Machado, C.S., Schmidt, E.M., Costa, P.M., Alves, A.P.N.N., Morais, T.M.F., Queiroz, M.G.R., Quináia, S.P., Rosa, M.R., Santos, J.M.T., Pessoa, C., Moraes, M.O., Lotufo, L.V.C., Sawaya, A.C.H.F., Eberlin, M.N., Torres, Y.R. (2011). In vivo antitumoural activity and composition of an oil extract of Brazilian propolis. Food Chemistry, 126, 1239-1245.
  13. Chan, G.C., Chan, W.K., Sze, D.M. (2009). The Effects of β-Glucan on Human, Immune and Cancer Cells. Journal of Hematology and Oncology, 25(2), 1-11.
  14. Chen, C.N., Weng, M.S., Wu, C.L., Lin, J.K. (2014). Comparison of Radical Scavenging Activity, Cytotoxic Effects and Apoptosis Induction in Human Melanoma Cells by Taiwa