Journals / Journal of Clinical Research in Pediatric Endocrinology / 2019 / Cilt: 11 - Sayı: 2

Evaluation of Normal Thyroid Tissue and Autoimmune Thyroiditis in Children Using Shear Wave Elastography

Pages
132–139
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: SWE is a useful imaging method that can be used with routine ultrasonography in evaluation of the thyroid in children.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: Shear wave elastography (SWE) is a user-independent ultrasonographic technique that evaluates tissue elasticity.
📊
Key Findings & Data:Methods: In total, 113 healthy children of whom 66 (58.4%) were girls and 57 children with autoimmune thyroiditis of whom 45 (78.9%) were girls were evaluated by SWE after B-mode ultrasound.
💡
Conclusion & Impact:Conclusion: SWE is a useful imaging method that can be used with routine ultrasonography in evaluation of the thyroid in children.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Objective: Shear wave elastography (SWE) is a user-independent ultrasonographic technique that evaluates tissue elasticity. It is used especially in the evaluation of thyroiditis and thyroid nodules when it is capable of distinguishing malignant from benign thyroiditis in adults. To date, no studies have evaluated SWE in pediatric thyroid patients. The aim of this study was to measure the elasticity of normal thyroid tissue in children and adolescents using SWE and to investigate its role in the diagnosis of pediatric autoimmune thyroiditis. Methods: In total, 113 healthy children of whom 66 (58.4%) were girls and 57 children with autoimmune thyroiditis of whom 45 (78.9%) were girls were evaluated by SWE after B-mode ultrasound. The quantitative evaluation of normal thyroid tissue in healthy children and those with autoimmune thyroiditis was performed using shear wave velocity (SWV) values (m/s). Thyroid antibodies were consistent with autoimmune thyroiditis. Data were compared using descriptive and analytical statistics and receiver-operating characteristic curves. Results: The mean ± standard deviation (range) of SWV value in thyroid parenchyma of the healthy children was 1.82±0.3 m/s (1.32- 2.37) m/s. There was a significant positive correlation between age and SWV values which increased with age. The average SWV value of thyroid parenchyma in children with autoimmune thyroiditis was 3.7±1.2 (2.59-6.25) m/s which was statistically significantly greater than in healthy children (p=0.00). The cut-off value for elasticity with the highest diagnostic accuracy was 2.39 m/s; sensitivity and specificity were 97.4% and 100% respectively. There was no correlation between elasticity, thyroid function tests and autoantibody concentrations (p>0.05). Conclusion: SWE is a useful imaging method that can be used with routine ultrasonography in evaluation of the thyroid in children.

🔖

Cite This Article

PALABIYIK, F. B., İNCİ, E., ÇAKIR, E. D. P., HOCAOĞLU, E. (2019). Evaluation of Normal Thyroid Tissue and Autoimmune Thyroiditis in Children Using Shear Wave Elastography. Journal of Clinical Research in Pediatric Endocrinology, Cilt: 11 - Sayı: 2, 132–139. https://ajindex.com/articles/190715

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Monpeyssen H, Tramalloni J, Poiree S, Helenon O, Correas JM. Elastography of the thyroid. Diagn Interv Imaging 2013;94:535-540
  2. Andrioli M, Persani L. Elastography techniques of thyroid gland:current status. Endocrine 2014;46:455-461
  3. Dudea SM, Botar-Jid C. Ultrasound elastography in thyroid disease Med Ultrason 2015;17:74-96
  4. Arda K, Ciledag N, Aktas E, Arıbas BK, Köse K. Qantitative assessment of normal soft tissue elasticity using shear wave ultrasound elastography. AJR Am J Roentgenol 2011;197:532-536
  5. Fukuhara T, Matsuda E, Endo Y, Takenobu M, Izawa S, Fujiwara K, Kitano H. Correlation between quantitative shear wave elastography and pathologic structures of thyroid lesions. Ultrasound Med Biol 2015;41:2326-2332
  6. Friedrich-Rust M, Romenski O, Meyer G, Dauth N, Holzer K, Grünwald F, Kriener S, Herrmann E, Zeuzem S, Bojunga J. Acoustic radiation force impulse imaging for the evluation of the thyroid gland:a limited patient feasibility study. Ultrasonics 2012;52:69-74
  7. Brown RS. Autoimmune thyroiditis in chilhood. J Clin Res Pediatr Endocrinol 2013;5(Suppl 1):45-49
  8. Lorini R, Gastaldi R, Traggiai C, Perucchin PP. Hashimoto’s thyroiditis. Pediatr Endocrinol Rev 2003;(1 Suppl 2):205-211
  9. Cosgrove D, Barr R, Bojunga J, Cantisani V, Chammas MC, Dighe M, Vinayak S, Xu JM, Dietrich CF. WFUMB guidelines and recommendations on the clinical use of ultrasound elastography:Part 4. Thyroid Ultrasound Med 2017;43:4-26
  10. Ceyhan Bilgici M, Sağlam D, Delibalta S, Yücel S, Tomak L, Elmalı M. Shear wave velocity of the healthy thyroid gland in children with acoustic radiation force impulse elastography. J Med Ultrason 2018;45:75-80
  11. Yucel S, Ceyhan Bilgici M, Kara C, Can Yilmaz G, Aydin HM, Elmali M, Tomak L, Saglam D. Acoustic radiation force impulse quantification in the evaluation of thyroid elasticity in pediatric patients with Hashimoto thyroiditis. J Ultrasound Med 2018;37:1143-1149
  12. Kandemirli SG, Bayramoglu Z, Caliskan E, Sari ZNA, Adaletli I. Quantitative assessment of thyroid gland elasticty with shear wave elastography in pediatric patients with Hashimoto’s thyroiditis. J Med Ultrason (2001) 2018;45:417-423
  13. Sporea I, Sirli R, Bota S, Vlad M, Popescu A, Zosin I. ARFI elastography for the evaluation of diffuse thyroid gland pathology: Preliminary result. World J Radiol 2012;4:174-178
  14. Vlad M, Golu I, Bota S, Vlad A, Timar B, Timar R, Sporea I. Real-time shear wave elastography may predict autoimmune thyroid disease.