SavedAdd your journal

Journals / E Journal of Cardiovascular Medicine / 2020 / Cilt: 8 - Sayı: 4

Evaluation of the Global Longitudinal Strain in FMF: In Relation with Duration of Illness

Erhan AYGÜN
Fatih Mehmet KELEŞOĞLU
Gafur DOĞDU
Ömer KUMAŞ
Rukiye Eker ÖMEROĞLU
Pages
186–192
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Speckle tracking ECG can provide the chance to reveal subclinical ventricular dysfunction before cardiac dysfunctions progress in children with FMF.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objectives: The aim of this study is to investigate the effects of Familial Mediterranean Fever (FMF) on cardiac function via speckle tracking echocardiography (ECG) in pediatric FMF patients without cardiac symptoms and to compare speckle tracking ECG results with the conventional echocardiographic outcomes.
📊
Key Findings & Data:Materials and Methods: A total of 50 FMF children aged between 5 and 19 years and 50 healthy children adjusted by age were evaluated for inclusion.
💡
Conclusion & Impact:Conclusion: Speckle tracking ECG can provide the chance to reveal subclinical ventricular dysfunction before cardiac dysfunctions progress in children with FMF.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Objectives: The aim of this study is to investigate the effects of Familial Mediterranean Fever (FMF) on cardiac function via speckle tracking echocardiography (ECG) in pediatric FMF patients without cardiac symptoms and to compare speckle tracking ECG results with the conventional echocardiographic outcomes. Materials and Methods: A total of 50 FMF children aged between 5 and 19 years and 50 healthy children adjusted by age were evaluated for inclusion. Conventional ECG of each participant was performed to investigate mechanical myocardial function. Global longitudinal strain (GLS) measurements were performed using 2D speckle tracking ECG. Results: The mean duration of illness among FMF patients was 4.6±3.1 years. There was no statistically significant relationship between sex and duration of illness (p>0.05). GLS values measured by two-dimensional speckle tracking between the groups were significantly lower in individuals diagnosed with FMF compared to the control group (-18.0±2.0/- 22.5±2.0; p<0.001). The relationship between disease duration and left ventricle-GLS values of individuals diagnosed with FMF was evaluated by spearman correlation analysis. It was observed that left ventricle-GLS values decreased statistically with increasing disease duration. Conclusion: Speckle tracking ECG can provide the chance to reveal subclinical ventricular dysfunction before cardiac dysfunctions progress in children with FMF.

🔖

Cite This Article

AYGÜN, E., KELEŞOĞLU, F. M., DOĞDU, G., KUMAŞ, Ö., ÖMEROĞLU, R. E. (2020). Evaluation of the Global Longitudinal Strain in FMF: In Relation with Duration of Illness. E Journal of Cardiovascular Medicine, Cilt: 8 - Sayı: 4, 186–192. https://ajindex.com/articles/190223

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (15)

  1. Ben-Chetrit E, Touitou I. Familial mediterranean fever in the world. Arthritis Rheum 2009;61:1447-53
  2. Sohar E, Gafni J, Pras M, Heller H. Familial mediterranean fever. A survey of 470 cases and review of the literature. Am J Med 1967;43:227-53
  3. Garcia-Gonzalez A, Weisman MH. The arthritis of familial mediterranean fever. Semin Arthritis Rheum 1992;22:139-50
  4. Lidar M, Doron A, Barzilai A, et al. Erysipelas-like erythema as the presenting feature of familial mediterranean fever. J Eur Acad Dermatol Venereol 2013;27:912-5
  5. Ebrahimi-Fakhari D, Schonland SO, Hegenbart U, et al. Familial mediterranean fever in germany: Clinical presentation and amyloidosis risk. Scand J Rheumatol 2013;42:52-8
  6. Kucuk A, Gezer IA, Ucar R, Karahan AY. Familial mediterranean fever. Acta Medica 2014;57:97-104
  7. Braun E, Schapira D, Guralnik L, Azzam ZS. Acute vasculitis with multiorgan involvement in a patient with familial mediterranean fever. Am J Med Sci 2003;325:363-4
  8. Ceylan O, Ozgur S, Orun UA, et al. Assessment of left ventricular functions with tissue doppler, strain, and strain rate echocardiography in patients with familial mediterranean fever. Anatol J Cardiol 2015;15:663-8
  9. Nesbitt GC, Mankad S, Oh JK. Strain imaging in echocardiography: Methods and clinical applications. Int J Cardiovasc Imaging 2009;25(Suppl 1):9-22
  10. Triantafyllou KA, Karabinos E, Kalkandi H, Kranidis AI, Babalis D. Clinical implications of the echocardiographic assessment of left ventricular long axis function. Clin Res Cardiol 2009;98:521-32
  11. Hatle L, Sutherland GR. Regional myocardial function a new approach. Eur Heart J 2000;21:1337-57
  12. Shave R, George K, Whyte G, et al. A comparison of doppler, tissue doppler imaging, and strain rate imaging in the assessment of postexercise left ventricular function. Appl Physiol Nutr Metab 2009;34:33-9
  13. Amzulescu MS, Langet H, Saloux E, et al. Improvements of myocardial deformation assessment by three-dimensional speckle-tracking versus two-dimensional speckle-tracking revealed by cardiac magnetic resonance tagging. J Am Soc Echocardiogr 2018;31:1021-33
  14. Petersen JW, Nazir TF, Lee L, Garvan CS, Karimi A. Speckle tracking echocardiography-determined measures of global and regional left ventricular function correlate with functional capacity in patients with and without preserved ejection fraction. Cardiovasc Ultrasound 2013;11:20
  15. Livneh A, Langevitz P, Zemer D, et al. Criteria for the diagnosis of familial mediter