SavedAdd your journal

Journals / Fiziksel Tıp ve Rehabilitasyon Bilimleri Dergisi / 2010 / Cilt: 13 - Sayı: 1

Düşük doz intratekal baklofen uygulamasına bağlı bradikardi

Bradycardia related to administration of low dose intrathecal baclofen

Bilge YILMAZ
İlknur TUĞCU
Evren YAŞAR
Rıdvan ALACA
Kamil YAZICIOĞLU
Pages
31–33
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It was determined after lower doses of ITB administration, and the suspicion of overdosing or withdrawal syndrome which were the main risks of ITB came out. , In this case presentation, we investigated the causes of this bradycardia with the review of present literature.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:We presented an unusual tetraplegic case with sinus bradycardia after intrathecal baclofen therapy (ITB).
📊
Key Findings & Data:We presented an unusual tetraplegic case with sinus bradycardia after intrathecal baclofen therapy (ITB).
💡
Conclusion & Impact:It was determined after lower doses of ITB administration, and the suspicion of overdosing or withdrawal syndrome which were the main risks of ITB came out. , In this case presentation, we investigated the causes of this bradycardia with the review of present literature.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

We presented an unusual tetraplegic case with sinus bradycardia after intrathecal baclofen therapy (ITB). It was determined after lower doses of ITB administration, and the suspicion of overdosing or withdrawal syndrome which were the main risks of ITB came out. , In this case presentation, we investigated the causes of this bradycardia with the review of present literature.

Özet

İntratekal baklofen tedavisi (ITB) sonrası sinüs bradikardisi olan alışılmadık bir tetraplejik vakayı sunduk. Bu, düşük doz ITB uygulaması sonrası tanımlandı ve aşırı doz veya çekilme sendromu şüphesi doğdu. Bu vaka sunumunda, mevcut literatürler derlenerek bu bradikardinin nedenlerini araştırdık.

🔖

Cite This Article

YILMAZ, B., TUĞCU, İ., YAŞAR, E., ALACA, R., YAZICIOĞLU, K. (2010). Düşük doz intratekal baklofen uygulamasına bağlı bradikardi. Fiziksel Tıp ve Rehabilitasyon Bilimleri Dergisi, Cilt: 13 - Sayı: 1, 31–33. https://ajindex.com/articles/189688

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (11)

  1. Stempien L, Tsai T. Intrathecal Baclofen Pump Use for Spasticity: A Clinical Survey. Am J of Phys Med Rehabil 2000;79:536-41
  2. Zahavi A, Geertzen JHB, Middel B, Staal M, Rietman JS. Long term effect (more than five years) of intrathecal baclofen on impairment, disability, and quality of life in patients with severe spasticity of spinal origin. J Neurol Neurosurg Psychiatry 2004;75:1553-7
  3. Dario A, Tomei G. A benefit-risk assessment of baclofen in severe spinal spasticity. Drug Saf 2004;27:799-818
  4. Armstrong RW, Steinbok P, Cochrane DD, Kube SD, Fife SE, Farrell K. Intrathecally administered baclofen for treatment of children with spasticity of cerebral origin. J Neurosurg 1997;87:409-14
  5. Dressnandt J, Konstanzer A, Weinzierl FX, Pfab R, Klingelhöfer J. Intrathecal baclofen in tetanus:four cases and a review of reported cases. Intensive Care Med 1997;23:896-902
  6. Smit C, Slim E. Heart conduction problems in a tetraplegic patient caused by a single therapeutic dosage of baclofen. Spinal cord 2007 Oct 9; [Epub ahead of print] 7. Perry HE, Wright RO, Shannon MW, Woolf AD. Baclofen overdose: drug experimentation in a group of adolescents. Pediatrics 1998;101:1045-8
  7. Landulpho CD, Dias AC, Colombari E. Cardiovascular mechanisms activated by microinjection of baclofen into NTS of conscious rats. Am J Physiol Heart Circ Physiol 2003;284:987-93
  8. Monassier L, Brandt CM, Bousquet P. Effects of centrally-acting glutamatergic modulators on cardiovascular responses to stress in humans. J Cardiol 2001;37:77-84
  9. Cohen MB, Gailey RA, McCoy GC. Atropine in the treatment of baclofen overdose. Am J Emerg Med 1986;4:552-3
  10. Silversides JA, Scott KC. Diabetes insipidus following overdose of baclofen and quetiapine. Anaesth Intensive Care 2009;37:319-20
  11. Castaño B, Benito J, Pires F, Ferreira S, Lopez R, Vidal J. Delirium secondary to intrathecal baclofen. Spinal Cord. 2009;47:477-80.