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Journals / Turkish Journal of Chemistry / 2012 / Cilt: 36 - Sayı: 3

Synthesis, characterization, and antioxidant activities of new trisubstituted triazoles

Kemal SANCAK
Yasemin ÜNVER
Dilek ÜNLÜER
Esra DÜĞDÜ
Gülcan KÖR
Pages
457–466
Publication Date
2012-03-01
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Among the chemicals tested, 4d, e, and g exhibited the highest degree of antioxidant activity.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:A series of new 4-(3,4dimethoxyphenethyl)-3,5-akyl/aryl-4H- 1,2,4-triazoles (3a-g) were obtained by reaction of ethyl N'-(alkylidene/arylidene)hydrazonate (1) and 2-(3,4-dimethoxy phenyl)ethanamine (2).
📊
Key Findings & Data:Compounds 4d, e, and g were synthesized from the reaction of corresponding compounds 3d, e, and g with BBr3, respectively.
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Conclusion & Impact:Among the chemicals tested, 4d, e, and g exhibited the highest degree of antioxidant activity.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Synthesis · 4-triazole · antioxidant activity

Abstract

A series of new 4-(3,4dimethoxyphenethyl)-3,5-akyl/aryl-4H- 1,2,4-triazoles (3a-g) were obtained by reaction of ethyl N'-(alkylidene/arylidene)hydrazonate (1) and 2-(3,4-dimethoxy phenyl)ethanamine (2). Compounds 4d, e, and g were synthesized from the reaction of corresponding compounds 3d, e, and g with BBr3, respectively. The 10 new compounds synthesized were characterized by elemental analyses, IR, 1H-NMR, and 13C-NMR spectral data. The structure of compound 3g was inferred through IR, 1H-, 13C-NMR, elemental analyses, and X-ray spectral techniques. In addition, the newly synthesized chemicals were screened for their antioxidant properties. Among the chemicals tested, 4d, e, and g exhibited the highest degree of antioxidant activity.

Özet

A series of new 4-(3,4dimethoxyphenethyl)-3,5-akyl/aryl-4H- 1,2,4-triazoles (3a-g) were obtained by reaction of ethyl N'-(alkylidene/arylidene)hydrazonate (1) and 2-(3,4-dimethoxy phenyl)ethanamine (2). Compounds 4d, e, and g were synthesized from the reaction of corresponding compounds 3d, e, and g with BBr3, respectively. The 10 new compounds synthesized were characterized by elemental analyses, IR, 1H-NMR, and 13C-NMR spectral data. The structure of compound 3g was inferred through IR, 1H-, 13C-NMR, elemental analyses, and X-ray spectral techniques. In addition, the newly synthesized chemicals were screened for their antioxidant properties. Among the chemicals tested, 4d, e, and g exhibited the highest degree of antioxidant activity.

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Cite This Article

SANCAK, K., ÜNVER, Y., ÜNLÜER, D., DÜĞDÜ, E., KÖR, G. (2012). Synthesis, characterization, and antioxidant activities of new trisubstituted triazoles. Turkish Journal of Chemistry, Cilt: 36 - Sayı: 3, 457–466. https://ajindex.com/articles/185250

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