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Journals / Turkish Journal of Chemistry / 2014 / Cilt: 38 - Sayı: 1

NH-acidities and Hammett correlation of 3-para substituted phenyl-1,2,4-oxadiazol-5(4H)-ones and 1,2 λ 43,5-oxathiadiazole 2-oxides in nonaqueous media

NH-acidities and Hammett correlation of 3-para substituted phenyl-1,2,4-oxadiazol-5(4H)-ones and 1,2 l43,5-oxathiadiazole 2-oxides in nonaqueous media

Nedime DÜRÜST
Yaşar DÜRÜST
Emine Özge GÖZLÜKAYA
Pages
56–62
Publication Date
2014-05-18
DOI
—
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⚡ TL;DR(Too Long; Didn't Read)

NH acidities of some 3-(p-substitutedphenyl)-1,2,4-oxadiazol-5(4H)-ones and 4-(p-substitutedphenyl)-1,2 l43,5-oxathiadiazole 2-oxides were determined in methanol by means of potentiometric titration with sodium methoxide. pKa values of the title compounds calculated from the potentiometric data were interpreted on the basis of structural effects caused by para-substituted groups on the phenyl ring by plotting pKa values versus Hammett sp+ constants, which gave excellent linear correlations.

📌 3 Key Takeaways

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Objective & Hypothesis:NH acidities of some 3-(p-substitutedphenyl)-1,2,4-oxadiazol-5(4H)-ones and 4-(p-substitutedphenyl)-1,2 l43,5-oxathiadiazole 2-oxides were determined in methanol by means of potentiometric titration with sodium methoxide. pKa values of the title compounds calculated from the potentiometric data were interpreted on the basis of structural effects caused by para-substituted groups on the phenyl ring by plotting pKa values versus Hammett sp+ constants, which gave excellent linear correlations.
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Key Findings & Data:NH acidities of some 3-(p-substitutedphenyl)-1,2,4-oxadiazol-5(4H)-ones and 4-(p-substitutedphenyl)-1,2 l43,5-oxathiadiazole 2-oxides were determined in methanol by means of potentiometric titration with sodium methoxide. pKa values of the title compounds calculated from the potentiometric data were interpreted on the basis of structural effects caused by para-substituted groups on the phenyl ring by plotting pKa values versus Hammett sp+ constants, which gave excellent linear correlations.
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Conclusion & Impact:NH acidities of some 3-(p-substitutedphenyl)-1,2,4-oxadiazol-5(4H)-ones and 4-(p-substitutedphenyl)-1,2 l43,5-oxathiadiazole 2-oxides were determined in methanol by means of potentiometric titration with sodium methoxide. pKa values of the title compounds calculated from the potentiometric data were interpreted on the basis of structural effects caused by para-substituted groups on the phenyl ring by plotting pKa values versus Hammett sp+ constants, which gave excellent linear correlations.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Potentiometry · oxadiazol-5(4H)-one · oxathiadiazol 2-oxide

Abstract

NH acidities of some 3-(p-substitutedphenyl)-1,2,4-oxadiazol-5(4H)-ones and 4-(p-substitutedphenyl)-1,2 l43,5-oxathiadiazole 2-oxides were determined in methanol by means of potentiometric titration with sodium methoxide. pKa values of the title compounds calculated from the potentiometric data were interpreted on the basis of structural effects caused by para-substituted groups on the phenyl ring by plotting pKa values versus Hammett sp+ constants, which gave excellent linear correlations.

Özet

NH acidities of some 3-(p-substitutedphenyl)-1,2,4-oxadiazol-5(4H)-ones and 4-(p-substitutedphenyl)-1,2 l43,5-oxathiadiazole 2-oxides were determined in methanol by means of potentiometric titration with sodium methoxide. pKa values of the title compounds calculated from the potentiometric data were interpreted on the basis of structural effects caused by para-substituted groups on the phenyl ring by plotting pKa values versus Hammett sp+ constants, which gave excellent linear correlations.

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Cite This Article

DÜRÜST, N., DÜRÜST, Y., GÖZLÜKAYA, E. Ö. (2014). NH-acidities and Hammett correlation of 3-para substituted phenyl-1,2,4-oxadiazol-5(4H)-ones and 1,2 λ 43,5-oxathiadiazole 2-oxides in nonaqueous media. Turkish Journal of Chemistry, Cilt: 38 - Sayı: 1, 56–62. https://ajindex.com/articles/184710

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