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Journals / Turkish Journal of Chemistry / 2015 / Cilt: 39 - Sayı: 5

Green and efficient synthesis of novel bispyrazoles through a tandem Knoevenagel and Michael type reaction using nanowire zinc oxide as a powerful and recyclable catalyst

KHALIL ESKANDARI
BAHADOR KARAMI
SAEED KHODABAKHSHI
SEYYED JAFAR HOSEINI
Pages
1069–1077
Publication Date
2015-12-04
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The synthetic method is operationally simple and affords product with high yields in short reaction times.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Zinc oxide nanowires (ZnO NWs) were prepared and characterized by scanning electron microscopy, powder X-ray diffraction, and transmission electron microscopy analyses.
📊
Key Findings & Data:ZnO NWs were then employed as heterogeneous and recyclable catalyst for green synthesis of some new and known bispyrazole derivatives through a tandem Knoevenagel and Michael type addition reaction of aromatic aldehyde and pyrazolone.
💡
Conclusion & Impact:The synthetic method is operationally simple and affords product with high yields in short reaction times.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Zinc oxide nanowire · bispyrazole · aldehyde

Abstract

Zinc oxide nanowires (ZnO NWs) were prepared and characterized by scanning electron microscopy, powder X-ray diffraction, and transmission electron microscopy analyses. ZnO NWs were then employed as heterogeneous and recyclable catalyst for green synthesis of some new and known bispyrazole derivatives through a tandem Knoevenagel and Michael type addition reaction of aromatic aldehyde and pyrazolone. The synthetic method is operationally simple and affords product with high yields in short reaction times.

Özet

Zinc oxide nanowires (ZnO NWs) were prepared and characterized by scanning electron microscopy, powder X-ray diffraction, and transmission electron microscopy analyses. ZnO NWs were then employed as heterogeneous and recyclable catalyst for green synthesis of some new and known bispyrazole derivatives through a tandem Knoevenagel and Michael type addition reaction of aromatic aldehyde and pyrazolone. The synthetic method is operationally simple and affords product with high yields in short reaction times.

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Cite This Article

ESKANDARI, K., KARAMI, B., KHODABAKHSHI, S., HOSEINI, S. J. (2015). Green and efficient synthesis of novel bispyrazoles through a tandem Knoevenagel and Michael type reaction using nanowire zinc oxide as a powerful and recyclable catalyst. Turkish Journal of Chemistry, Cilt: 39 - Sayı: 5, 1069–1077. https://ajindex.com/articles/184562

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References (9)

  1. Okandeji, B. O.; Sello, J. K. J. Org. Chem. 2009, 74, 5067–5070.
  2. Ruijter, E.; Scheffelaar, R.; Orru, R. V. A. Angew. Chem., Int. Ed. 2011, 50, 6234–6246.
  3. Born, D. V.; Herscheid, J. K. D. M.; Orru, R. V. A.; Vugts, D. J. Chem. Commun. 2013, 49, 4018–4020.
  4. Silveira, C. C.; Boeck, P.; Braga, A. L. Tetrahedron Lett. 2000, 41, 1867–1869.
  5. Silveira, C. C.; Mendes, S. R.; Martins, G. M.; Schlosser, S. C.; Kaufman, T. S. Tetrahedron 2013, 69, 9076–9085.
  6. Habibi, A.; Eskandari, K.; Alizadeh, A. Phosphorus Sulfur Silicon Relat. Elem. 2012, 187, 1109–1117.
  7. Karami, B.; Eskandari, K.; Azizi, M. Lett. Org. Chem. 2013, 10, 722–732.
  8. Okandeji, B. O.; Gordon, J. R.; Sello, J. K. J. Org. Chem. 2008, 73, 5595–5597.
  9. Ruijter, E.; Orru, R. V. A. Drug Discovery Today: Technol. 2013, 10, 15–20., 2, 8010–8013. 26.Wang, W.; Wang, S. X.; Qin, X. Y.; Li, J. T. Synth. Commun. 2005, 35. 1263–1269. 27.Sujatha, K.; Shanthi, G.; Selvam, N. P.; Manoharan, S.; Perumal, P. T.; Rajendran, M. Bioorg. Med. Chem. Lett. Gomathi, A.; Hoseini, S. J.; Rao, C. N. R. J. Mater. Chem. 2009, 19, 988–995.