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AI Summary & Key Takeaways
AI Insight⚡ TL;DR(Too Long; Didn't Read)
The synthesized Michael adducts were subjected to intramolecular cyclization to give heteroaryl substituted γ-lactams in good to high yields under mild reaction conditions.
📌 3 Key Takeaways
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Objective & Hypothesis:Aliphatic nitroalkanes with different functional groups were synthesized from the Michael addition reactions of active methylene compounds 2 and nitrovinyl arenes 1 in high yields.
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Key Findings & Data:Aliphatic nitroalkanes with different functional groups were synthesized from the Michael addition reactions of active methylene compounds 2 and nitrovinyl arenes 1 in high yields.
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Conclusion & Impact:The synthesized Michael adducts were subjected to intramolecular cyclization to give heteroaryl substituted γ-lactams in good to high yields under mild reaction conditions.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:γ-Lactam · aliphatic nitroalkanes · Michael addition
Abstract
Aliphatic nitroalkanes with different functional groups were synthesized from the Michael addition reactions of active methylene compounds 2 and nitrovinyl arenes 1 in high yields. The synthesized Michael adducts were subjected to intramolecular cyclization to give heteroaryl substituted γ-lactams in good to high yields under mild reaction conditions.
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Cite This Article
ÇINAR, S., ÜNALEROĞLU, C. (2018). Facile synthesis of heteroaryl substituted -lactams from nitrovinyl arenes. Turkish Journal of Chemistry, Cilt: 42 - Sayı: 1, 29–35. https://ajindex.com/articles/184488