After adjusting the patients' sex, age, urbanization level, and comorbidities, the hazard ratio obtained from our multivariable Cox model was 1.19.Conclusion: Our study findings indicate that patients with AS are more likely to develop nephrolithiasis than non-AS patients.
📌 3 Key Takeaways
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Objective & Hypothesis:Objectives: This study aims to investigate the correlation of ankylosing spondylitis (AS) with nephrolithiasis by performing a nationwide populationbased cohort study.Patients and methods: The data used in this retrospective cohort study were collected from the Taiwan National Health Insurance Research database.
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Key Findings & Data:The study included a total of 3,334 AS patients (1,914 males, 1,420 females; mean age 44.51±16.83 years; range 22 to 79 years) and 13,336 non-AS patients (7,656 males, 5,680 females; mean age 44.27±17.01 years; range 21 to 78 years) who had been followed-up on an average of 6.78 years and 6.75 years, respectively, between January 2000 and December 2008.Results: The percentage of newly diagnosed nephrolithiasis was 4.8% in all study subjects.
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Conclusion & Impact:After adjusting the patients' sex, age, urbanization level, and comorbidities, the hazard ratio obtained from our multivariable Cox model was 1.19.Conclusion: Our study findings indicate that patients with AS are more likely to develop nephrolithiasis than non-AS patients.
🔬Design:Modeling & Simulation
📍Scope:2000 Verileri
⚙️Variables:Domain Parameters
Abstract
Objectives: This study aims to investigate the correlation of ankylosing spondylitis (AS) with nephrolithiasis by performing a nationwide populationbased cohort study.Patients and methods: The data used in this retrospective cohort study were collected from the Taiwan National Health Insurance Research database. The study included a total of 3,334 AS patients (1,914 males, 1,420 females; mean age 44.51±16.83 years; range 22 to 79 years) and 13,336 non-AS patients (7,656 males, 5,680 females; mean age 44.27±17.01 years; range 21 to 78 years) who had been followed-up on an average of 6.78 years and 6.75 years, respectively, between January 2000 and December 2008.Results: The percentage of newly diagnosed nephrolithiasis was 4.8% in all study subjects. However, the percentages of newly diagnosed nephrolithiasis were 5.76% and 4.58% in the AS and non-AS cohorts, respectively. After adjusting the patients' sex, age, urbanization level, and comorbidities, the hazard ratio obtained from our multivariable Cox model was 1.19.Conclusion: Our study findings indicate that patients with AS are more likely to develop nephrolithiasis than non-AS patients.
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Cite This Article
SHIH, M. T., TANG, S. H., CHA, T. L., WU, S. T., CHIANG, J. H., CHEN, W. C. (2016). The Risk of Nephrolithiasis Among Patients With Ankylosing Spondylitis: A Population-Based Cohort Study. art, Cilt: 31 - Sayı: 4, 346–352. https://ajindex.com/articles/178189
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