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Journals / ANKEM Dergisi / 2009 / Cilt: 23 - Sayı: 2

E-test yöntemiyle metisiline dirençli staphyloccoccus aureus suşlarının linezolide in-vitro duyarlılıği

İn vitro susceptibility of methicillin-resistant staphyloccoccus aureus to linezolid by E-test method

İlhan AFŞAR
Nükhet KURULTAY
Aslı Gamze ŞENER
Gül Süreyya YURTSEVER
Pages
51–53
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This drug could be a promising therapeutic option against MRSA.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The incidence of methicillin-resistant gram-positive infections continue to increase and linezolid may provide new options to treat patients.
📊
Key Findings & Data:The in vitro susceptibility of a total of 88 MRSA isolates to linezolid was investigated by the E-test.
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Conclusion & Impact:This drug could be a promising therapeutic option against MRSA.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The incidence of methicillin-resistant gram-positive infections continue to increase and linezolid may provide new options to treat patients. The aim of this study was to investigate the in vitro susceptibility of methicillin-resistant Staphylococcus aureus (MRSA) strains isolated from clinical specimens to linezolid. The in vitro susceptibility of a total of 88 MRSA isolates to linezolid was investigated by the E-test. All MRSA isolates were found to be susceptible to linezolid (Minimal inhibitory concentration < 4.0 mg/l). The results of the present study demonstrated that linezolid has a good in vitro activity against MRSA in Turkey. This drug could be a promising therapeutic option against MRSA.

Özet

Metisiline dirençli Gram pozitif infeksiyonların insidasındaki artış devam etmekte ve linezolid hastalara yeni tedavi seçeneği sağlamaktadır. Çalışmanın amacı; klinik örneklerden soyutlanan metisiline dirençli Staphylococcus aureus (MRSA) suşlarının linezolide in-vitro duyarlılığını araştırmaktır. Toplam 88 MRSA suşunun linezolide in-vitro duyarlılığı E-test yöntemiyle araştırılmış, tüm suşlar duyarlı bulunmuştur (MİK<4.0 mg/l). Bu çalışmadaki sonuçlar linezolidin Türkiye’deki MRSA suşlarına in-vitro iyi etkinliği olduğunu göstermektedir. Bu ilaç MRSA infeksiyonlarında iyi bir tedavi seçeneği sağlamaktadır.

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Cite This Article

AFŞAR, İ., KURULTAY, N., ŞENER, A. G., YURTSEVER, G. S. (2009). E-test yöntemiyle metisiline dirençli staphyloccoccus aureus suşlarının linezolide in-vitro duyarlılıği. ANKEM Dergisi, Cilt: 23 - Sayı: 2, 51–53. https://ajindex.com/articles/171811

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