Journals / Journal of Health Sciences and Medicine / 2026 / Volume: 9 Issue: 6

Changes in knowledge, attitudes, and vaccination intentions following an HPV educational intervention among medical students: a single-group pretest–posttest study

Ömer Karaşahin(Department of Infectious Diseases and Clinical Microbiology, University of Health Sciences, Erzurum City Hospital)0000-0002-4245-1534
Mehmet Ali Tüz(Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Balikesir University,)0000-0002-9676-7681
Enes Dalmanoğlu(Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Balikesir University,)0000-0003-4425-5649
Ayten Yanık(Erzurum City Hospital)0009-0006-2825-4434
İrem Tataroğlu(Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Balikesir University)0009-0003-8217-3801
Berat Karaman(Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Balikesir University,)0009-0005-5357-0845
Pages
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Publication Date
2026-10-25
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

These findings suggest that educational interventions should address persistent knowledge gaps together with economic and risk-perception barriers that may influence HPV vaccine acceptance.

📌 3 Key Takeaways

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Objective & Hypothesis:Aims: This study aimed to evaluate changes in human papillomavirus (HPV) knowledge, attitudes toward HPV vaccination, and vaccination intentions following a structured HPV educational intervention among medical students.
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Key Findings & Data:Methods: This single-group, uncontrolled pretest-posttest study was conducted among 312 medical students in years 1-5 at Balıkesir University Faculty of Medicine between February and June 2026.
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Conclusion & Impact:These findings suggest that educational interventions should address persistent knowledge gaps together with economic and risk-perception barriers that may influence HPV vaccine acceptance.
🔬Design:Lab & Field Experiment
📍Scope:2026 Verileri
⚙️Variables:Human papillomavirus · HPV vaccination · students

Abstract

Aims: This study aimed to evaluate changes in human papillomavirus (HPV) knowledge, attitudes toward HPV vaccination, and vaccination intentions following a structured HPV educational intervention among medical students. Methods: This single-group, uncontrolled pretest-posttest study was conducted among 312 medical students in years 1-5 at Balıkesir University Faculty of Medicine between February and June 2026. HPV knowledge was assessed using the validated Turkish 33-item HPV Knowledge Scale (HPV-KS). Attitudes toward HPV vaccination were evaluated using a 20-item Likert-type section, and vaccination intentions were assessed using matched pre- and post-intervention questions. Participants received a standardized face-to-face HPV educational intervention between the pretest and posttest assessments. Results: The total HPV-KS score increased from 19.37±5.89 to 23.57±4.08 (mean change, 4.20; 95% CI, 3.70-4.70; p<0.001). The composite attitude score increased more modestly from 66.98±6.54 to 67.75±6.87 (p=0.001). Among unvaccinated students, personal vaccination intention increased from 68.2% to 82.8% (p<0.001), while intention to receive the vaccine if provided free of charge increased from 77.6% to 83.3% (p=0.005). The most frequently reported post-intervention barriers were cost or exclusion from the routine immunization program (48.0%) and perceived absence of risky behavior (37.2%). Conclusion: Structured HPV education was associated with a marked improvement in HPV knowledge and favorable changes in vaccination intentions among medical students, whereas changes in attitudes were limited. These findings suggest that educational interventions should address persistent knowledge gaps together with economic and risk-perception barriers that may influence HPV vaccine acceptance.

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Cite This Article

Sarıkaya, R. İ., Çağlar, Y., Karaşahin, Ö., Tüz, M. A., Dalmanoğlu, E., Yanık, A., Tataroğlu, İ., Karaman, B. (2026). Changes in knowledge, attitudes, and vaccination intentions following an HPV educational intervention among medical students: a single-group pretest–posttest study. Journal of Health Sciences and Medicine, Volume: 9 Issue: 6. https://ajindex.com/articles/1668059

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References (24)

  1. World Health Organization. Cervical cancer. Published July 3, 2026. Accessed August 7, 2026. https://www.who.int/news-room/fact-sheets/detail/cervical-cancer
  2. World Health Organization. Human papillomavirus and cancer. Published March 5, 2024. Accessed August 7, 2026. https://www.who.int/news-room/fact-sheets/detail/human-papilloma-virus-and-cancer
  3. World Health Organization. Global Strategy to Accelerate the Elimination of Cervical Cancer as a Public Health Problem. World Health Organization; 2020. https://www.who.int/publications/i/item/9789240014107
  4. Bruel S, Rakotomampionona Z, Gignon M, et al. The intentions of French health university students to recommend and to receive the HPV vaccine are mainly influenced by vaccine knowledge, confidence in vaccines and personal HPV vaccination. Vaccine. 2024;42(8):1934-1940. doi:10.1016/j.vaccine.2024.02.033
  5. Liu A, Ho FK, Chan LKL, et al. Chinese medical students’ knowledge, attitude and practice towards human papillomavirus vaccination and their intention to recommend the vaccine. J Paediatr Child Health. 2018;54(3):302-310. doi:10.1111/jpc.13693
  6. Alhetheli G, Alhumaid R, Alajlan S, et al. Knowledge, awareness, and willingness toward the HPV vaccine among medical students at Qassim University: a cross-sectional study. Vaccines (Basel). 2026;14(6):529. doi:10.3390/vaccines14060529
  7. Du EY, Adjei Boakye E, Taylor DB, et al. Medical students’ knowledge of HPV, HPV vaccine, and HPV-associated head and neck cancer. Hum Vaccin Immunother. 2022;18(6):2109892. doi:10.1080/21645515.2022.2109892
  8. Unal E. Knowledge of human papilloma virus and vaccine hesitancy among health sciences students in Türkiye. Sci Rep. 2026;16(1):22699. doi:10.1038/s41598-026-62858-9
  9. Afacan Yıldırım E, Kızık TN. Human papillomavirus (HPV) awareness and vaccine hesitancy among medical students: a cross-sectional study on knowledge, stigma, and preventive behavior. Turk J Dermatol. 2025;19(3):118-125. doi:10.4274/tjd.galenos.2025.05706
  10. Yang X, Ye Q, Su S, Yang Y, Li X. Effectiveness of a pre-test/post-test model in HPV health education among undergraduate medical students. BMC Med Educ. 2025;25(1):158. doi:10.1186/s12909-025-06717-7
  11. Waller J, Ostini R, Marlow LAV, McCaffery K, Zimet G. Validation of a measure of knowledge about human papillomavirus (HPV) using item response theory and classical test theory. Prev Med. 2013;56(1):35-40. doi:10.1016/j.ypmed.2012.10.028
  12. Demir Bozkurt F, Özdemir S. Validity and reliability of a Turkish version of the human papillomavirus knowledge scale: a methodological study. J Turk Ger Gynecol Assoc. 2023;24(3):177-186. doi:10.4274/jtgga.galenos.2023.2022-10-9
  13. Elsaid NMA, Ismail HAH, Salim AA, et al. The effect of educational intervention program on knowledge and willingness of medical students to take cervical cancer screening and human papillomavirus vaccine: a quasi-experimental study. J Family Community Med. 2025;32(3):207-216. doi:10.4103/jfcm.jfcm_45_25
  14. Berenson AB, Hirth JM, Fuchs EL, Chang M, Rupp RE. An educational intervention to improve attitudes regarding HPV vaccination and comfort with counseling among US medical students. Hum Vaccin Immunother. 2020;16(5):1139-1144. doi:10.1080/21645515.2019.1692558
  15. Ajzen I. The theory of planned behavior. Organ Behav Hum Decis Process. 1991;50(2):179-211. doi:10.1016/0749-5978(91)90020-T
  16. Zomordi G, Moradi M, Hasanzadeh M, Ghavami V. The effect of education based on the theory of planned behavior on the intention of vaccination against human papillomavirus in female students: a controlled educational trial. J Educ Health Promot. 2022;11:237. doi:10.4103/jehp.jehp_1145_21
  17. Korkmaz D, Turunç HN, Özarslan YA, et al. Assessment of HPV vaccine knowledge levels among medical faculty students: a comprehensive examination in the Turkish context. Med Sci Discov. 2023;10(9):655-661. doi:10.36472/msd.v10i9.1033
  18. Costa AdS, Gomes JM, Germani ACCG, et al. Knowledge gaps and acquisition about HPV and its vaccine among Brazilian medical students. PLoS One. 2020;15(3). doi:10.1371/journal.pone.0230058
  19. Bunting SR, Morris S, Chael J, Feinstein BA, Hazra A, Garber SS. Knowledge of human papillomavirus vaccination: a multi-institution, cross-sectional study of allopathic and osteopathic medical students. PLoS One. 2023;18(1). doi:10.1371/journal.pone.0280287
  20. Solis-Torres N, Braverman-Diaz I, Rivera-Morales LA, et al. Medical students’ knowledge about human papillomavirus (HPV), HPV vaccine and head and neck cancer. Hum Vaccin Immunother. 2024;20(1):2344248. doi:10.1080/21645515.2024.2344248
  21. Erbağcı E, Türkmenoğlu B, Mete AÖ, Karaoğlan İ. Knowledge about human papillomavirus infection among fourth, fifth and sixth year medical faculty students. FLORA. 2024;29(4):430-440. doi:10.5578/flora.2024041181
  22. Li W, Jin Y, Li X, Jin M. Human papillomavirus and vaccine knowledge, willingness, and uptake among university students: a systematic review and meta-analysis. BMC Public Health. 2025;25(1):4268. doi:10.1186/s12889-025-25626-4
  23. Remkes A, Gheit T, Martínez-Pérez GZ, Fusco D. Moving beyond the female-only paradigm: arguments for accelerating the global gender-neutral human papillomavirus vaccination. Cancer Control. 2026;33:10732748261466385. doi:10.1177/10732748261466385
  24. Chandeying N, Khantee P, Puetpaiboon S, Thongseiratch T. Gender-neutral vs. gender-specific strategies in school-based HPV vaccination programs: a systematic review and meta-analysis. Front Public Health. 2025;13:1460511. doi:10.3389/fpubh.2025.1460511