Journals / Ağrı / 2013 / Cilt: 25 - Sayı: 2

Ortostatik baş ağrısının çok nadir bir nedeni: İntrakranial hipotansiyonlu 13 olgunun etyoloji, tedavi ve prognozlarının gözden geçirilmesi

Intracranial hypotension is a rare cause of orthostatic headache: a review of the etiology, treatment and prognosis of 13 cases

Journal
Ağrı
Pages
69–77
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conservative treatments should be considered initially, however if conservative treatments fail, epidural blood patches must be applied.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: The aim of this investigation is to examine the causes, clinical picture, treatment, and prognosis of spontaneous intracranial hypotension, a rare cause of orthostatic headache, among the cases presenting in our clinic.
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Key Findings & Data:Methods: Thirteen cases (5 males and 8 females), diagnosed with spontaneous intracranial hypotension in our clinic between January 1st, 2009 and October 30th, 2011, were included in this study.
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Conclusion & Impact:Conservative treatments should be considered initially, however if conservative treatments fail, epidural blood patches must be applied.
🔬Design:Research Article
📍Scope:2009 Verileri
⚙️Variables:Domain Parameters

Abstract

Objectives: The aim of this investigation is to examine the causes, clinical picture, treatment, and prognosis of spontaneous intracranial hypotension, a rare cause of orthostatic headache, among the cases presenting in our clinic. Methods: Thirteen cases (5 males and 8 females), diagnosed with spontaneous intracranial hypotension in our clinic between January 1st, 2009 and October 30th, 2011, were included in this study. The presenting symptoms, treatment, findings on cranial magnetic resonance imaging, cerebrospinal fluid pressure measured at lumbar puncture (in available patients), and the healing period of the patients were recorded. Results: Five patients with orthostatic headache and accompanying symptoms were treated with bed rest, increase in oral fluid intake, intravenous hydration and caffeine, and experienced a complete recovery. Complete recovery was observed in two patients (15.3%) within 10 days, in another two (15.3%) within 15 days and in one patient (7.6%) within 21 days. Headache and other clinical symptoms significantly regressed within 30 days in four patients (37.6%) who received similar treatment, but a mild headache persisted intermittently during follow-up in these individuals. As the headache had not resolved after 30 days, an epidural blood patch was applied in these four cases (37.6%) and the clinical picture completely improved within 10 to 15 days. Conclusion: Spontaneous intracranial hypotension should primarily be suspected in cases complaining about postural head- ache and contrast-enhanced cranial imaging should be performed. The presence of cranial nerve paralysis and pyramidal tract signs should b considered. Conservative treatments should be considered initially, however if conservative treatments fail, epidural blood patches must be applied.

Özet

Amaç: Ortostatik başağrısının nadir bir deneni olan spontan intrakraniyal hipotansiyonun nedenleri, kliniği, tedavi ve prognozunu kliniğimizde izlenen olgular eşliğinde gözden geçirmek. Gereç ve Yöntem: Ocak 2009-30 Ekim 2011 tarihleri arasında kliniğimizde tanı alan 5 erkek ve 8 kadın olmak üzere 13 tane spon- tan intrakraniyal hipotansiyon olgusu çalışmaya dahil edildi. Hastalar geliş semtomları, uygulanan tedavi, kraniyal MRG bulguları, uygun hastalarda yapınla BOS basınç değerleri ve klinik iyileşme süreleri değerlendirilerek incelendi. Bulgular: Ortostatik baş ağrısının ve eşlik eden bulguların yatak istirahati, oral sıvı alımının artırılması, intravenöz hidrasyon ve kafein tedavisi uygulanan iki hastada (%15.3) 10 günde iki hastada (%15.3) 15 günde bir hastada (%7.6) 21 günde tamamen düzeldiği görüldü. Benzer tedavi uygulanan dört (%37.6) olguda başağrısı ve diğer klinik özelliklerinin 30 gün içerisinde belirgin olarak gerilediği ancak periyodik takiplerinde hafif şiddette baş ağrılarının aralıklı olarak devam ettiği gözlendi. 30 gün sonrasında ortostatik baş ağrısı gerilemeyen olgulara uygulanan epidural kan yaması sonrasında 10-15 gün içerisinde kliniklerinin tamamen düzeldiği görüldü. Sonuç: Postural baş ağrısı tarifleyen olgularda öncelikle spontan intrakraniyal hipotansiyondan (SIH) mutlaka şüphe edilmeli ve kontrastlı kraniyal görüntüleme yapılmalıdır. Kraniyal sinir paralizileri ve piramidal traktus bulguları olabileceği unutulmamalıdır. Epidural kan yamaları konservatif tedavinin yetersiz kaldığı olgulara uygulanmalıdır.

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Cite This Article

GÜLER, S., ÇAĞLI, B., UTKU, U., ÜNLÜ, E., ÇELİK, Y. H. (2013). Ortostatik baş ağrısının çok nadir bir nedeni: İntrakranial hipotansiyonlu 13 olgunun etyoloji, tedavi ve prognozlarının gözden geçirilmesi. Ağrı, Cilt: 25 - Sayı: 2, 69–77. https://ajindex.com/articles/165103

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References (15)

  1. Schievink WI. Spontaneous spinal cerebrospinal fluid leaks: a review. Neurosurg Focus 2000
  2. 9(1):8. 2. Mokri B, Krueger BR, Miller GM, Piepgras DG. Meningeal gad- olinium enhancement in low pressure headache. Ann Neurol 1991
  3. Wang YF, Lirng JF, Fuh JL, Hseu SS, Wang SJ. Heavily T2- weighted MR myelography vs CT myelography in spontane- ous intracranial hypotension. Neurology 2009
  4. Tsai PH, Fuh JL, Lirng JF, Wang SJ. Heavily T2-weighted MR myelography in patients with spontaneous intracranial hy- potension: a case-control study. Cephalalgia 2007
  5. 27(8):929- 34. 5. Headache Classification Subcommittee of the International Headache Society. The International Classification of Head- ache Disorders: 2nd edition. Cephalalgia 2004
  6. Pannullo SC, Reich JB, Krol G, Deck MD, Posner JB. MRI chang- es in intracranial hypotension. Neurology 1993
  7. 43(5):919-26. 7. Tosaka M, Sato N, Fujimaki H, Tanaka Y, Kagoshima K, Taka- hashi A, et al. Diffuse pachymeningeal hyperintensity and subdural effusion/hematoma detected by fluid-attenuated inversion recovery MR imaging in patients with sponta- neous intracranial hypotension. AJNR Am J Neuroradiol 2008
  8. 29(6):1164-70. 8. Schievink WI. Spontaneous spinal cerebrospinal fluid leaks and intracranial hypotension. JAMA 2006
  9. 295(19):2286-96. 9. Franzini A, Messina G, Nazzi V, Mea E, Leone M, Chiapparini L, et al. Spontaneous intracranial hypotension syndrome: a novel speculative physiopathological hypothesis and a novel patch method in a series of 28 consecutive patients. J Neurosurg 2010
  10. 112(2):300-6. 10.Mokri B. The Monro-Kellie hypothesis: applications in CSF volume depletion. Neurology 2001
  11. 56(12):1746-8. 11.Ferrante E, Savino A, Sances G, Nappi G. Spontaneous intra- cranial hypotension syndrome: report of twelve cases. Head- ache 2004
  12. 44(6):615-22. 12.Albayram S, Asik M, Hasiloglu ZI, Dikici AS, Erdemli HE, Al- tintas A. Pathological contrast enhancement of the oculo- motor and trigeminal nerves caused by intracranial hypo- tension syndrome. Headache 2011
  13. 51(5):804-8. 13.Hochman MS, Naidich TP, Kobetz SA, Fernandez-Maitin A. Spontaneous intracranial hypotension with pachymenin- geal enhancement on MRI. Neurology 1992
  14. 42(8):1628-30. 14. Grimaldi D, Mea E, Chiapparini L, Ciceri E, Nappini S, Savoiar- do M, et al. Spontaneous low cerebrospinal pressure: a mini review. Neurol Sci 2004
  15. Liu H, Kaye A, Comarda N, Li M. Paradoxical postural cere- brospinal fluid leak-induced headache: repor