Investigations of the effects on the blood glucose levels of surgery and general anaesthesia with xylazine-ketamine and xylazine-pentobarbital sodium in healthy dogs

Abstract

Ip this study, the effects of surgery and general anaesthesia· that is with xylazine -ketamine hydrochloride and xylazine-pentobarbital sodium used common/y in carnivore, on the blood glucose /eve/s, were investigated. The study was carried out in two groups, that each was consist of 5 dogs. The investigation was carried out in two parts. In the first part, the anima/s in the first group were anaesthetized with xylazine -ketamine hydrochloride and the anima/s in the second group were anaesthetized with xylazine-pentobarbital sodium. In the second part, the same anima/s usedin first part were anaesthetized with the same anaesthetic combinations, and than experimental laparatomie was made. In the both parts, 1-2 ml blood samples were taken from anima/s before anaesthesia and operation then on the 30 th, 60 th, 90 th, and 120 th minutes after anaesthesia and operation. Glucose values were detedmined with spectophotometer. As a ~esult, 1t may be said that pentobarbital sodium used in study has no hyperglycemic effect, but xylazine and ketarnine hydrochloride has significant hyperglycemic effect..