Journals / Haseki Tıp Bülteni / 2019 / Cilt: 57 - Sayı: 1

Evaluation of Electroencephalography Findings in Isolated Hypocalcemia Patients

İzole Hipokalsemili Hastalarda Elektroensefalografi Bulgularının Değerlendirilmesi

Pages
51–56
DOI
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Conclusion: Our study showed that various EEG findings, such as slowed background activity and epileptiform abnormalities, may be seen in isolated hypocalcemia patients even in the absence of clinical findings and these EEG findings may improve in normocalsemic period.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: In our study, we aimed to analyze electroencephalography (EEG) findings in patients with hypocalcemia and to investigate possible relationship between calcium (Ca) level and EEG abnormalities and whether there was any change in EEG findings when serum Ca level returns to normal.
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Key Findings & Data:Methods: Seventeen consecutive patients, who were admitted to the Endocrinology, Neurology and General Surgery Clinics at İstanbul Şişli Hamidiye Etfal Training and Research Hospital with a corrected serum Ca level of 8.5 mg/dL) in follow-up.
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Conclusion & Impact:Conclusion: Our study showed that various EEG findings, such as slowed background activity and epileptiform abnormalities, may be seen in isolated hypocalcemia patients even in the absence of clinical findings and these EEG findings may improve in normocalsemic period.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: In our study, we aimed to analyze electroencephalography (EEG) findings in patients with hypocalcemia and to investigate possible relationship between calcium (Ca) level and EEG abnormalities and whether there was any change in EEG findings when serum Ca level returns to normal. Methods: Seventeen consecutive patients, who were admitted to the Endocrinology, Neurology and General Surgery Clinics at İstanbul Şişli Hamidiye Etfal Training and Research Hospital with a corrected serum Ca level of 8.5 mg/dL) in follow-up. Results: EEG abnormalities were detected in nine (53%) of 17 patients. EEG examination revealed slow background activity in seven patients (41%) and epileptiform abnormalities in two (12%) patients. In follow-up, normocalcemic period was observed in seven patients. EEG findings were improved in two of eight patients who had slow background activity and one of two patients with epileptiform activity in the normocalcemic period. Conclusion: Our study showed that various EEG findings, such as slowed background activity and epileptiform abnormalities, may be seen in isolated hypocalcemia patients even in the absence of clinical findings and these EEG findings may improve in normocalsemic period.

Özet

Amaç: Çalışmamızda hipokalsemi olan hastalardaki elektroensefalografi (EEG) bulgularını araştırmayı, kalsiyum (Ca) düzeyi ile EEG anormallikleri arasında olası ilişkiyi göstermeyi ve serum Ca düzeyi normale döndüğünde EEG bulgularında değişiklik olup olmadığını incelemeyi amaçladık. Yöntemler: Çalışmamıza İstanbul Şişli Hamidiye Etfal Eğitim ve Araştırma Hastanesi Endokrinoloji, Nöroloji, ve Genel Cerrahi Poliklinikleri’ne başvurmuş, düzeltilmiş serum Ca değeri 8,5 mg/dL) yükselen hastalara kontrol EEG incelemesi yapıldı. Bulgular: On yedi hastanın dokuzunda (%53) çeşitli EEG anormallikleri saptanmıştır. EEG bulguları yedi (%41) hastada zemin aktivitesinde yavaşlama, iki (%12) hastada ise epileptiform anormallikler gösterdi. Takiplerde yedi hastada normokalsemik dönem izlendi. Zemin aktivitesinde yavaşlama olan beş hastanın ikisinde, epileptiform aktivitesi olan iki hastanın birinde normokalsemik dönemde EEG bulgularının düzeldiği gözlendi. Sonuç: Çalışmamız izole hipokalsemili hastalarda klinik bulgu olmasa da, zemin aktivitesinde yavaşlama ve epileptiform anormallikler gibi çeşitli EEG bulguları görülebileceğini ve bu EEG bulgularının normokalsemik dönemde düzelebileceğini göstermiştir.

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Cite This Article

TİMER, S. M., TİMER, E., YÜKSELEN, N. P., PAZARCI, N. K., ORKEN, D. N. (2019). Evaluation of Electroencephalography Findings in Isolated Hypocalcemia Patients. Haseki Tıp Bülteni, Cilt: 57 - Sayı: 1, 51–56. https://ajindex.com/articles/164772

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References (8)

  1. Riggs JE. Neurological manifestations of electrolyte disturbances. Neurology Clinics 2002;20:227-39.
  2. Rose BD, Post TW. Clinical physiology of acid-base and electrolyte disorders. 5th ed. McGraw-Hill, 2001. Kunze K. Metabolic encephalopathies. J Neurol 2002;249:1150-9. Gupta MM. Medical emergencies associated with disorders of calcium homeostasis. J Assoc Physicians India 1989;37:629- 31. Messing RO, Simon RP. Seizures as a manifestation of systemic disease. Neurol Clin 1986;4:563-84.
  3. Belluzzo M, Monti F, Pizzolato G. A case of hypocalcemiarelated epilepsia partialis continua. Seizure 2011;20:720-2.
  4. Dimich A, Bedrossian PB, Wallach S. Hypoparathyroidism: clinical observations in 34 patients. Arch Intern Med 1967;120:449-58.
  5. Fonseca OA, Calverley JR. Neurological manifestations of hypoparathyroidism. Arch Intern Med 1967;120:202-6.
  6. Modi S, Tripathi M, Saha S, Goswami R. Seizures in patients with idiopathic hypoparathyroidism: effect of antiepileptic drug withdrawal on recurrence of seizures and serum calcium control. Eur J Endocrinol 2014;170:777-83.
  7. Armelisasso C, Vaccaria ML, Pontecorvi A, Mazza S. Tonicclonic seizures in a patient with primary hypoparathyroidism: a case report. Clin EEG Neurosci 2004;35:97-9. Castilla-Guerra L, del Carmen Fernández-Moreno M, LópezChozas JM, Fernández-Bolaños R. Electrolytes disturbances and seizures. Epilepsia 2006;47:1990-8. Lin CC. EEG manifestations in metabolic encephalopathy. Acta Neurol Taiwan 2005;14:151-61. Kaplan PW. The EEG in metabolic encephalopathy and coma. J Clin Neurophysiol 2004;21:307-18.
  8. Bindu M, Harinarayana CV. Hypoparathyroidism: a rare treatable cause of epilepsy - report of two cases. Eur J Neurol 2006;13:786-8.