Journals / Recent Trends in Pharmacology / 2026 / Volume: 2 Issue: 2

Amygdalin (Vitamin B17) Effect on Glioblastoma: Focus on Oxidant Capacity and Antioxidant Status

Sıdıka Genç(BILECIK SEYH EDEBALI UNIVERSITY)0000-0003-0000-5103
Kübra Karabulut(BILECIK SEYH EDEBALI UNIVERSITY)0009-0002-7052-6086
Esmanur Niğde(BILECIK SEYH EDEBALI UNIVERSITY)0009-0004-6007-472X
Yunus Emre Aydin(BILECIK SEYH EDEBALI UNIVERSITY)0009-0001-4123-8192
Beyzanur Aydın(BILECIK SEYH EDEBALI UNIVERSITY)0009-0003-5102-6016
Alperen Enes Aydın(BILECIK SEYH EDEBALI UNIVERSITY)0009-0009-1630-6366
Ali Taghizadehghalehjoughi(BİLECİK ŞEYH EDEBALİ ÜNİVERSİTESİ)0000-0002-3506-0324
Pages
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Publication Date
2024-08-29
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Vit B17 can increase oxidative stress in T98G cells and decrease cell viability

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: Amygdalin (Vitamin B-17) is a type of vitamin, naturally found in many fruits and plants.
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Key Findings & Data:The aim of the study was the evaluation of Amygdalin effect on the oxidant capacity and oxidant status of the T98G cancer cells.
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Conclusion & Impact:Conclusion: Vit B17 can increase oxidative stress in T98G cells and decrease cell viability
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Amygdalin · TAC · TOS

Abstract

Objective: Amygdalin (Vitamin B-17) is a type of vitamin, naturally found in many fruits and plants. The aim of the study was the evaluation of Amygdalin effect on the oxidant capacity and oxidant status of the T98G cancer cells. A T98G cell line was used in the study. Cell viability and oxidative stress evaluation were done. Methods: Amygdalin was used at 1, 4, and 8 µg/mL doses. TAC and TOS values were measured. Results: According to the result, amygdalin 8 µg/mL shows the highest anticancer effects. TAC level was 3.2 Trolox Equiv/L and TOS was 3.6 H2O2 Equiv/L. Conclusion: Vit B17 can increase oxidative stress in T98G cells and decrease cell viability

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Cite This Article

Genç, S., Karabulut, K., Niğde, E., Aydin, Y. E., Aydın, B., Aydın, A. E., Taghizadehghalehjoughi, A. (2024). Amygdalin (Vitamin B17) Effect on Glioblastoma: Focus on Oxidant Capacity and Antioxidant Status. Recent Trends in Pharmacology, Volume: 2 Issue: 2. https://doi.org/10.62425/rtpharma.1523732

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