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Journals / Karatekin Üniversitesi Fen Fakültesi Dergisi / 2025 / Volume: 4 Issue: 1

Investigation of the Electrochemical Behavior of Epinephrine with Polycatechol/SiO₂NP Modified Electrodes

Polikatekol/SiO₂NP Modifiye Elektrotlarla Epinefrinin Elektrokimyasal Davranışının İncelenmesi

Merve Yılmaz(ÇANKIRI KARATEKİN ÜNİVERSİTESİ)0000-0003-3690-2455
Melike Bilgi Kamaç(Çankırı Karatekin University)0000-0002-3381-7522
Ayşenur Yılmaz Kabaca(ÇANKIRI KARATEKİN ÜNİVERSİTESİ)0000-0002-1189-405X
Şahin Toparli(ÇANKIRI KARATEKİN ÜNİVERSİTESİ)0009-0008-5740-4053
Faruk Terzioğlu(ÇANKIRI KARATEKİN ÜNİVERSİTESİ)0009-0005-0904-5170
Emir Ateş(ÇANKIRI KARATEKİN ÜNİVERSİTESİ)0009-0006-4258-6101
Pages
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Publication Date
2025-12-31
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

These findings suggest that the SPCE/PCA/SiO₂NP electrode can be used as an electrochemical sensor for the analysis of epinephrine and similar neurotransmitters.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Epinephrine is an important neurotransmitter that plays a role in many areas of the human body, from the central nervous system to the cardiovascular system.
📊
Key Findings & Data:In this study, the electrochemical behavior of epinephrine was investigated on polycatechol/SiO₂NP-modified screen-printed carbon electrodes (SPCE).
💡
Conclusion & Impact:These findings suggest that the SPCE/PCA/SiO₂NP electrode can be used as an electrochemical sensor for the analysis of epinephrine and similar neurotransmitters.
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:Epinephrine · polycatechol · silicon oxide nanoparticles

Abstract

Epinephrine is an important neurotransmitter that plays a role in many areas of the human body, from the central nervous system to the cardiovascular system. In this study, the electrochemical behavior of epinephrine was investigated on polycatechol/SiO₂NP-modified screen-printed carbon electrodes (SPCE). Polycatechol (PCA) was modified electrochemically, while SiO₂NPs were physically adsorbed. Optimization of the number of cycles was performed for the formation of PCA on the SPCE surface, and optimization of the amount of SiO₂NP modification was performed. The electrochemical behavior of epinephrine on the prepared SPCE/PCA/SiO₂NP electrodes was investigated by cyclic voltammetry. PCA and SiO₂NP exhibited a synergistic effect, increasing the electrode's conductivity and exhibiting an electrocatalytic effect against epinephrine. These findings suggest that the SPCE/PCA/SiO₂NP electrode can be used as an electrochemical sensor for the analysis of epinephrine and similar neurotransmitters.

Özet

Epinefrin, insan vücudunda merkezi sinir sisteminden kardiyovasküler sistemlere kadar birçok yer de rol alan önemli bir nörotransmiterdir. Bu çalışmada, polikatekol/SiO₂NP modifiyeli yüzey baskılı karbon elektrotlarda (SPCE) epinefrinin elektrokimyasal davranışı incelenmiştir. Polikatekol (PCA) elektrokimyasal yöntemle, SiO₂NP’ler fiziksel adsorpsiyon ile modifiye edilmiştir. PCA’nın SPCE yüzeyinde oluşturulmasında, döngü sayısı optimizasyonu, SiO₂NP’lerin modifikasyonunda miktar optimizasyonu yapılmıştır. Hazırlanan SPCE/PCA/SiO₂NP elektrotlarda epinefrinin elektrokimyasal davranışı dönüşümlü voltametri ile incelenmiştir. PCA ve SiO₂NP sinerjik bir göstererek elektrodun iletkenliğini artırmış ve epinefrine karşı elektrokatalitik etki göstermiştir. Bu bulgular, SPCE/PCA/SiO₂NP elektrotunun, epinefrin ve benzer yapıdaki nörotransmiterlerin analizinde elektrokimyasal sensör olarak kullanılabileceğini ortaya koymaktadır.

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Cite This Article

Yılmaz, M., Kamaç, M. B., Kabaca, A. Y., Toparli, Ş., Terzioğlu, F., Ateş, E. (2025). Investigation of the Electrochemical Behavior of Epinephrine with Polycatechol/SiO₂NP Modified Electrodes. Karatekin Üniversitesi Fen Fakültesi Dergisi, Volume: 4 Issue: 1. https://ajindex.com/articles/1645859

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