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Journals / Acıbadem Üniversitesi Sağlık Bilimleri Dergisi / 2019 / Sayı: 2

A Patient Admitted With Diabetic Ketoacidosis and Developing Secondary Hemophagocytic Syndrome

DIABETIK KETOASIDOZ TANISIYLA YATIRILAN VE SEKONDER HEMOFAGOSITIK SENDROM GELIŞEN BIR OLGU

Seher ERDOĞAN
Alper GÖK
Ali BAY
Mehmet BOŞNAK
Pages
322–324
Publication Date
2019-06-01
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We described a patient who was admitted to the intensive care unit with a diagnosis of diabetic ketoacidosis and transferred to the ward when her general condition improved, but who was also diagnosed with hemophagocytic lymphohistiocytosis by bone marrow investigation performed due to a resistant fever, splenomegaly, bicytopenia and hyperferritinemia

📌 3 Key Takeaways

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Objective & Hypothesis:Hemophagocytic lymphohistiocytosis is characterized by high body temperature, splenomegaly, bicytopenia, hypertriglyceridemia, hyperferritinemia, hypofibrinogenemia, decreased natural killer cell activity, increased soluble CD25 activity and the presence of hemophagocytosis in organs such as the bone marrow, the lymph glands, spleen and liver.
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Key Findings & Data:Hemophagocytic lymphohistiocytosis is characterized by high body temperature, splenomegaly, bicytopenia, hypertriglyceridemia, hyperferritinemia, hypofibrinogenemia, decreased natural killer cell activity, increased soluble CD25 activity and the presence of hemophagocytosis in organs such as the bone marrow, the lymph glands, spleen and liver.
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Conclusion & Impact:We described a patient who was admitted to the intensive care unit with a diagnosis of diabetic ketoacidosis and transferred to the ward when her general condition improved, but who was also diagnosed with hemophagocytic lymphohistiocytosis by bone marrow investigation performed due to a resistant fever, splenomegaly, bicytopenia and hyperferritinemia
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Hemophagocytic lymphohistiocytosis · Diabetes Mellitus

Abstract

Hemophagocytic lymphohistiocytosis is characterized by high body temperature, splenomegaly, bicytopenia, hypertriglyceridemia, hyperferritinemia, hypofibrinogenemia, decreased natural killer cell activity, increased soluble CD25 activity and the presence of hemophagocytosis in organs such as the bone marrow, the lymph glands, spleen and liver. We described a patient who was admitted to the intensive care unit with a diagnosis of diabetic ketoacidosis and transferred to the ward when her general condition improved, but who was also diagnosed with hemophagocytic lymphohistiocytosis by bone marrow investigation performed due to a resistant fever, splenomegaly, bicytopenia and hyperferritinemia

Özet

Hemofagositik lenfohistiositoz, yüksek ateş, splenomegali, bisitopeni, hipertrigliseridemi, hiperferritinemi, hipofibrinojenemi, doğal öldürücü hücre aktivitesinde azalma, çözünür solüble CD25 aktivitesinde artma, kemikiliği, lenfbezi, dalak, karaciğer gibi organlarda hemofagositoz varlığı ile karakterizedir. Burada diabetik ketoasidoz tanısı ile yoğun bakım ünitesine yatırılan,genel durumunun düzelmesi üzerine serviste takibine devam edilen ancak dirençli ateş, splenomegali, bisitopeni, hiperferritinemi nedeniyle yapılan kemikiliği incelemesi ile hemofagositik lenfohistiositoz tanısı alan hasta sunulmuştur

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Cite This Article

ERDOĞAN, S., GÖK, A., BAY, A., BOŞNAK, M. (2019). A Patient Admitted With Diabetic Ketoacidosis and Developing Secondary Hemophagocytic Syndrome. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi, Sayı: 2, 322–324. https://ajindex.com/articles/162890

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References (3)

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