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Journals / European Journal of Life Sciences / 2026 / Volume: 5 Issue: 2

Thiazole: A promising scaffold in medicinal chemistry

Abdüllatif Karakaya(BULENT ECEVIT UNIVERSITY)0009-0003-9619-6705
Emine Rana Bağci(AFYONKARAHISAR HEALTH SCIENCES UNIVERSITY)0009-0004-7452-0532
Betül Kaya(BILECIK SEYH EDEBALI UNIVERSITY)0000-0002-1713-9485
Ulviye Acar Çevik(ANADOLU UNIVERSITY)0000-0003-1879-1034
Zafer Asım Kaplancıklı(ANADOLU UNIVERSITY)0000-0003-2252-0923
Pages
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Publication Date
2026-08-31
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This review covers and highlights the most recently reported studies on thiazole-based derivatives with pharmacological potential.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Thiazole, a five-membered heterocyclic skeleton found in numerous commercially marketed drugs and various natural products, has gained significant attention in the field of medicinal chemistry.
📊
Key Findings & Data:Thiazole derivatives have diverse therapeutic potential, including neuroprotective, antidiabetic, antioxidant, antimicrobial, anti-inflammatory, anticancer, antihypertensive, and antitubercular activities.
💡
Conclusion & Impact:This review covers and highlights the most recently reported studies on thiazole-based derivatives with pharmacological potential.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Biological activity · heterocyclic compounds · thiazole

Abstract

Thiazole, a five-membered heterocyclic skeleton found in numerous commercially marketed drugs and various natural products, has gained significant attention in the field of medicinal chemistry. Thiazole derivatives have diverse therapeutic potential, including neuroprotective, antidiabetic, antioxidant, antimicrobial, anti-inflammatory, anticancer, antihypertensive, and antitubercular activities. The unique electronic and pharmacophoric features of the thiazole ring facilitate specific interactions with various biological targets. This review covers and highlights the most recently reported studies on thiazole-based derivatives with pharmacological potential.

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Cite This Article

Karakaya, A., Bağci, E. R., Kaya, B., Çevik, U. A., Kaplancıklı, Z. A. (2026). Thiazole: A promising scaffold in medicinal chemistry. European Journal of Life Sciences, Volume: 5 Issue: 2. https://doi.org/10.55971/EJLS.1929137

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