Journals / Haseki Tıp Bülteni / 2020 / Cilt: 58 - Sayı: 4

Neck Dissection in Early-stage Squamous Cell Carcinoma of the Lower Lip: Mid-term Treatment Results

Erken Evre Alt Dudak Skuamöz Hücreli Kanserde Boyun Diseksiyonu: Orta Dönem Tedavi Sonuçları

Pages
333–337
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Elective neck dissection should be performed in these high-risk patients.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: To evaluate the mid-term treatment results in early-stage squamous cell carcinoma (SCC) of the lower lip and to investigate the effect of tumor depth and size on neck metastasis.
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Key Findings & Data:Methods: The study included 52 patients who were operated between 2010 and 2017 for early-stage primary SSC of the lip with negative surgical margins and without oral commissure involvement T1 and T2 without lymph node or distant metastasis.
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Conclusion & Impact:Elective neck dissection should be performed in these high-risk patients.
🔬Design:Research Article
📍Scope:2010 Verileri
⚙️Variables:Domain Parameters

Abstract

Aim: To evaluate the mid-term treatment results in early-stage squamous cell carcinoma (SCC) of the lower lip and to investigate the effect of tumor depth and size on neck metastasis. Methods: The study included 52 patients who were operated between 2010 and 2017 for early-stage primary SSC of the lip with negative surgical margins and without oral commissure involvement T1 and T2 without lymph node or distant metastasis. Patients with missing data or patients with a history of additional malignancy at the time of diagnosis were excluded from the study (n=13). The data of the remaining 39 patients were further analyzed. Results: Fifteen patients (38.5%) were identified as having pT1 and 24 patients (61.5%), pT2. The mean tumor size was 16.8 mm and the mean invasion depth was 6.3 mm. Neck dissection was performed in 22 (56.4%) patients (6/15 pT1 patients and 16/24 pT2 patients). Lymph node involvement was reported in two (9.09%) of 22 patients. Both patients had pT2 stage tumors. Recurrence was observed in one patient (patient with pT2 tumor). The 5-year survival rate was calculated as 82.05%. Conclusion: In early-stage SCC of the lower lip, a tumor size greater than 21.5 mm and depth of tumor invasion greater than 7 mm are associated with increased neck metastasis. Elective neck dissection should be performed in these high-risk patients.

Özet

Amaç: Erken evre alt dudak skuamöz hücreli kanserde (SHK) orta dönem tedavi sonuçlarını değerlendirmek; tümör çap ve derinliğinin boyun metastazına etkisini araştırmak. Yöntemler: Çalışmaya 2010-2017 yılları arasında erken evre (lenf nodü ya da uzak metastazı olmayan T1 ve T2 hastalar) primer alt dudak SHK nedeni ile opere edilen, dudak komissürünün tutulmadığı ve cerrahi sınırları temiz olan 52 hasta dahil edildi. Eksik verisi olan hastalar ya da tanı anında ek malignite öyküsü olan hastalar çalışma dışı bırakıldı (n=13). Kalan 39 hastanın verileri ileri analiz edildi. Bulgular: On beş hasta (%38,5) pT1 ve 24 hasta (%61,5) pT2 olarak belirlendi. Ortalama tümör boyutu 16,8 mm ve ortalama invazyon derinliği 6,3 mm idi. Hastaların 22’sine (%56,4) (pT1 hastaların 6/15’ine ve pT2 hastaların 16/24’üne) boyun diseksiyonu yapıldı. Toplam 22 hastanın ikisinde (%9,09) lenf nodu tutulumu rapor edildi. Bu iki hasta da pT2 evre tümöre sahip idi. Bir hastada (pT2 tömöre sahip hasta) nüks görüldü. Beş yıllık sağkalım oranı %82,05 olarak hesaplandı. Sonuç: Erken evre alt dudak SHK’de tümör boyutunun 21,5 mm’den ve derinliğinin 7 mm’nin büyük olması artmış boyun metastazı ile ilişkilidir. Yüksek risk grubundaki bu hastalara elektif boyun diseksiyonu yapılmalıdır.

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Cite This Article

BAYRAM, Ö., AÇIKALIN, R. M. (2020). Neck Dissection in Early-stage Squamous Cell Carcinoma of the Lower Lip: Mid-term Treatment Results. Haseki Tıp Bülteni, Cilt: 58 - Sayı: 4, 333–337. https://ajindex.com/articles/162358

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