Journals / Rize Tıp Dergisi / 2026 / Cilt: 1 Sayı: 3

THE RELATIONSHIP BETWEEN LUNG INVOLVEMENT LEVEL AND LABORATORY PARAMETERS IN COVID-19 PCR-POSITIVE PATIENTS

COVİD-19 PCR POZİTİF HASTALARDA AKCİĞER TUTULUM DÜZEYİ İLE LABORATUVAR PARAMETRELERİ ARASINDAKİ İLİŞKİ

Merve Altıntop(Gümüşhane Kürtün Devlet Hastanesi)0000-0002-3207-7753
Kerem Uzun(Haçkalıbaba Devlet Hastanesi)0000-0001-9087-9335
Büşra Usluoğlu(Yahyalı Toplum Sağlığı Merkezi)0000-0002-7152-6419
Aslıhan Aşkın(RECEP TAYYİP ERDOĞAN ÜNİVERSİTESİ, TIP FAKÜLTESİ)0000-0003-2314-3349
Serdar Karakullukçu(KARADENİZ TEKNİK ÜNİVERSİTESİ, TIP FAKÜLTESİ)0000-0001-7673-7699
Cuneyt Ardıç(RECEP TAYYİP ERDOĞAN ÜNİVERSİTESİ, TIP FAKÜLTESİ)0000-0001-8018-9314
Pages
1–15
Publication Date
2024-09-30
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It should be kept in mind that lymphocyte, CRP, LDH and hematological rates, which are measured by investigating biochemical blood parameters in clinics where imaging is not possible, may be associated with lung involvement and prognosis of Covid-19 infection.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: The aim of our study is to examine the relationship between the level of uptake of the planet with cell Covid-19 PCR positivity and laboratory data in the Covid emergency polyclinic of the X University Training and Research Hospital.
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Key Findings & Data:Materials and Methods: Data from 224 Covid-19 PCR positive patients who applied to the Covid emergency outpatient clinic of X University Training and Research Hospital between March 2021 and September 2021, whose thoracic CT was taken and laboratory parameters were studied, were used.
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Conclusion & Impact:It should be kept in mind that lymphocyte, CRP, LDH and hematological rates, which are measured by investigating biochemical blood parameters in clinics where imaging is not possible, may be associated with lung involvement and prognosis of Covid-19 infection.
🔬Design:Araştırma Makalesi
📍Scope:2021 Verileri
⚙️Variables:Covid-19 · CORADS · Trombosit

Abstract

Objectives: The aim of our study is to examine the relationship between the level of uptake of the planet with cell Covid-19 PCR positivity and laboratory data in the Covid emergency polyclinic of the X University Training and Research Hospital. Materials and Methods: Data from 224 Covid-19 PCR positive patients who applied to the Covid emergency outpatient clinic of X University Training and Research Hospital between March 2021 and September 2021, whose thoracic CT was taken and laboratory parameters were studied, were used. Results: Of the 224 patients who participated in the study, 52.2% (n=117) were female patients, and 63.8% (n=143) were patients between the ages of 18-64. The CORADS classification of 53.6% (n=120) of the patients was 5-6 on thorax CT. As the lymphocyte level in the blood decreased, lung involvement increased on CT (p<0.004). As CRP, LDH, and fibrinogen levels in the blood increased, lung involvement increased (p<0.001). As the neutrophil/lymphocyte ratio, LDH/lymphocyte ratio and Platelet/lymphocyte ratio increased, uptake in CT increased (p<0.001, p<0.001 and p<0.002, respectively). As the lymphocyte/CRP ratio decreased, CT uptake increased (p<0.001). Conclusion: Our study revealed that the increase in blood parameters such as lymphopenia, CRP, LDH, and fibrinogen increases lung involvement and increases hospitalization and intensive care unit admission. It should be kept in mind that lymphocyte, CRP, LDH and hematological rates, which are measured by investigating biochemical blood parameters in clinics where imaging is not possible, may be associated with lung involvement and prognosis of Covid-19 infection.

Özet

Amaç: Çalışmamızın amacı X Üniversitesi Eğitim Araştırma Hastanesi Covid acil polikliniğine başvuran Covid-19 PCR pozitifliği olan hastalarda akciğer tutulum düzeyi ile laboratuvar parametreleri arasındaki ilişkiyi araştırmaktır. Gereç ve Yöntem: X Üniversitesi Eğitim Araştırma Hastanesi Covid acil polikliniğine Mart 2021-Eylül 2021 tarihleri arasında başvuran, toraks BT çekilen ve laboratuvar parametreleri çalışılan Covid-19 PCR pozitif 224 hastanın verileri kullanılmıştır. Bulgular: Çalışmaya katılan 224 hastanın %52,2’si(n=117) kadın hastaydı, %63,8’i (n=143) 18-64 yaş aralığındaki hastalardan oluşmaktaydı. Hastaların %53,6’sının (n=120) Toraks BT’de CORADS sınıflaması 5-6 idi. Kanda lenfosit düzeyi azaldıkça BT’de akciğer tutulumu artmaktaydı (p<0,004). Kandaki CRP, LDH ve fibrinojen düzeyi arttıkça akciğer tutulumu artmaktaydı (p<0,001). Nötrofil/lenfosit oranı, LDH/lenfosit oranı ve Trombosit/lenfosit oranı arttıkça BT’de tutulum artmaktaydı (sırasıyla p<0,001, p<0,001 ve p<0,002). Lenfosit/CRP oranı azaldıkça BT tutulumu artmaktaydı (p<0,001). Sonuç: Çalışmamız kan parametrelerinden lenfopeni, CRP, LDH, fibrinojen artışı akciğer tutulumunu arttırdığını, hastanede ve yoğun bakım yatışını arttırdığını ortaya koymuştur. Görüntüleme olanağının olmadığı kliniklerde biyokimyasal kan parametreleri araştırılarak bakılan lenfosit, CRP, LDH ve hematolojik oranların Covid-19 enfeksiyonunun akciğer tutulumuyla ve prognozu ile ilişkili olabileceği akılda tutulmalıdır.

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Cite This Article

Altıntop, M., Uzun, K., Usluoğlu, B., Aşkın, A., Karakullukçu, S., Ardıç, C. (2024). THE RELATIONSHIP BETWEEN LUNG INVOLVEMENT LEVEL AND LABORATORY PARAMETERS IN COVID-19 PCR-POSITIVE PATIENTS. Rize Tıp Dergisi, Cilt: 1 Sayı: 3, 1–15. https://ajindex.com/articles/1620544

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References (2)

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