Journals / HRÜ Uluslararası Diş Hekimliği ve Oral Araştırmalar Dergisi / 2026 / Volume: 5 Issue: 2

Regenerative Endodontic Treatment Applications in Immature Teeth: A Case Series

İMMATÜR DİŞLERDE REJENERATİF ENDODONTİK TEDAVİ UYGULAMALARI: BİR VAKA SERİSİ

Şahap Karakaya(KAHRAMANMARAŞ SÜTÇÜ İMAM ÜNİVERSİTESİ)0009-0004-8715-4906
Esra Balkanlıoğlu(Kahramanmaraş Sütçü İmam Üniversitesi)0009-0009-0903-7129
Aliye Kamalak(KAHRAMANMARAŞ SÜTÇÜ İMAM ÜNİVERSİTESİ)0000-0003-2103-0826
Pages
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Publication Date
2025-08-29
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

During the 12-month follow-up period post-treatment, we observed resolution of symptoms, significant periapical healing, and partial root formation.

📌 3 Key Takeaways

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Objective & Hypothesis:Regenerative endodontic therapy is a treatment modality that facilitates continued root formation in immature teeth with necrotic pulp and periapical radiolucency.
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Key Findings & Data:This study presents the application of regenerative endodontic treatment (RET) and concentrated growth factor (CGF) scaffolds in four distinct patients with necrotic pulp and asymptomatic apical periodontitis.
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Conclusion & Impact:During the 12-month follow-up period post-treatment, we observed resolution of symptoms, significant periapical healing, and partial root formation.
🔬Design:Case Report
📍Scope:Comprehensive Sample
⚙️Variables:immature permanent teeth · regenerative endodontics · revascularization

Abstract

Regenerative endodontic therapy is a treatment modality that facilitates continued root formation in immature teeth with necrotic pulp and periapical radiolucency. The most frequently observed causes of necrosis in an immature root include decay, improper endodontic treatments, and trauma. Necrosis of the dental pulp may adversely affect long-term tooth survival and preservation, potentially serving as a bacterial reservoir that can infect periapical tissue and the maxillofacial space. This study presents the application of regenerative endodontic treatment (RET) and concentrated growth factor (CGF) scaffolds in four distinct patients with necrotic pulp and asymptomatic apical periodontitis. During the 12-month follow-up period post-treatment, we observed resolution of symptoms, significant periapical healing, and partial root formation.

Özet

Rejeneratif endodontik yönetim, periapikal radyolüsensi ve nekrotik pulpa ile olgunlaşmamış dişler için sürekli kök oluşumunu basitleştiren uygun bir tedavidir. Olgunlaşmamış bir kökte en sık görülen sağlık sorunları arasında çürük, yanlış endodontik tedaviler ve travmanın neden olduğu pulpa nekrozu yer alır. Diş pulpasının nekrozu, uzun süreli diş sağkalımını ve korunmasını etkileyebilir ve periapikal dokuyu ve maksillofasiyal boşluğu enfekte eden bir bakteri kaynağı olarak hizmet edebilir. Bu çalışmada, nekrotik pulpa ve asemptomatik apikal periodontitisi olan 4 farklı hastada rejeneratif endodontik tedavi (RET) olarak konsantre büyüme faktörü(CGF) iskeleleri tedavisinin uygulanmasını sunuyoruz. Tedavi sonrası 12 aylık bir takip boyunca, semptomların çözüldüğünü ve önemli periapikal iyileşme ile kısmi bir kök oluşumunu gözlemledik.

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Cite This Article

Karakaya, Ş., Balkanlıoğlu, E., Kamalak, A. (2025). Regenerative Endodontic Treatment Applications in Immature Teeth: A Case Series. HRÜ Uluslararası Diş Hekimliği ve Oral Araştırmalar Dergisi, Volume: 5 Issue: 2. https://doi.org/10.61139/ijdor.1592081

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