Journals / Çocuk Enfeksiyon Dergisi / 2017 / Cilt: 11 - Sayı: 1

Microbiological and Antimicrobial Profile of Urinary Tract Infection in Children from a Teaching Hospital in South India

Güney Hindistan’da Bir Eğitim Hastanesindeki Çocuklarda Üriner Sistem Enfeksiyonlarının Mikrobiyolojik ve Antimikrobiyal Profili

Pages
19–22
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Development of regional surveillance programs is necessary for implementation of national UTI guidelines.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Urinary tract infections are an important healthcare issue and are responsible for nearly 3% of all infections among the pediatric population.
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Key Findings & Data:Material and Methods: In this study, records of all urine isolates and their antibiotic susceptibility profile from pediatric patients (1 month to 15 years) visiting a teaching hospital in south India in between June 2012 and December 2012 were evaluated.
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Conclusion & Impact:Development of regional surveillance programs is necessary for implementation of national UTI guidelines.
🔬Design:Research Article
📍Scope:2012 · 342 samples
⚙️Variables:Domain Parameters

Abstract

Objective: Urinary tract infections are an important healthcare issue and are responsible for nearly 3% of all infections among the pediatric population. There are increasing reports on rising antibiotic resistance and these reports stress the continual surveillance of antimicrobial efficacy, particularly in countries with wide antibiotic abuse. This retrospective study aims to analyze the resistance of bacterial isolates to commonly used antibiotics in pediatric populations. Material and Methods: In this study, records of all urine isolates and their antibiotic susceptibility profile from pediatric patients (1 month to 15 years) visiting a teaching hospital in south India in between June 2012 and December 2012 were evaluated. Results: Of 342 samples tested, 62 (18.1%) showed significant growth, and 42(67.8%) were from children under 5 years of age, with male predominate. Escherichia coli (48.4%) the most prevalent urinary pathogen, resistant to cephalosporin (87.5%) and fluroquinolones (81.7%) and lowest resistance to nitrofurantoin (30%) and aminoglycoside (38.3%), Conclusion: The uropathogens causing UTI in the pediatric population are highly resistant to most of the antibiotics recommended for empiric use in the therapy of UTI. Development of regional surveillance programs is necessary for implementation of national UTI guidelines.

Özet

Giriş: İdrar yolu enfeksiyonları önemli bir sağlık sorunu olmakla birlikte pediatrik popülasyon arasında görülen bütün enfeksiyonların %3’ünden sorumludur. Yükselen antibiyotik direnci ile ilgili her geçen gün sayısı ar-tan raporlar özellikle antibiyotik suistimalinin yaygın olduğu ülkelerde antimikrobiyal etkinliğin devamlı takibinin yapılmasının gerekliliğinin altını çizmektedir. Bu retrospektif çalışma, bakteriyel izolatların pediatrik popülasyonda yaygın biçimde kullanılan antibiyotiklere karşı direncini incelemeyi amaçlamaktadır. Gereç ve Yöntemler: Bu çalışmada, Haziran 2012 ile Aralık 2012 tarihleri arasında güney Hindistan’da bir eğitim hastanesini ziyaret eden pediat-rik hastaların (1 aylıktan 15 yaşa kadar) idrar izolatları ve onların antibi-yotik duyarlılıklarına ait kayıtlar değerlendirildi. Bulgular: Test edilen 342 örnekten 62’sinde (%18.1) önemli ölçüde üre-me görüldü ve bunların 42 (%67.8)’si beş yaş altı ağırlıklı olarak erkek popülasyonda elde edildi. En yaygın üriner patojeni olan Escherichia coli (%48.4) sefalosporin (%87.5) ve florokinolonlara (%81.7) en yüksek direnci gösterirken en düşük direnci nitrofurantoin (%30) ve aminogli-kozite (%38.3) gösterdi. Sonuç: Pediatrik popülasyonda idrar yolu enfeksiyonuna (İYE) yol açan üriner patojenler, İYE tedavisinde ampirik kullanım için önerilen antibi-yotiklerin birçoğuna karşı yüksek oranda dirençliler. Bölgesel denetleme programlarının geliştirilmesi ulusal İYE kılavuzunun uygulamaya kon-masında gereklidir.

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Cite This Article

KALAL, B. S., PATEL, R. B. (2017). Microbiological and Antimicrobial Profile of Urinary Tract Infection in Children from a Teaching Hospital in South India. Çocuk Enfeksiyon Dergisi, Cilt: 11 - Sayı: 1, 19–22. https://ajindex.com/articles/161569

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